Latar belakang: Rabies adalah penyakit yang 99% disebabkan oleh gigitan anjing, hampir 100% berakibat fatal, namun dapat dicegah melalui pemberian vaksin rutin pada anjing dan setelah gigitan pada manusia. Provinsi Bali mencatat kasus gigitan hewan penular rabies (HPR) tertinggi di Indonesia dan masih ditemukan kematian. Maka, perilaku vaksinasi anjing peliharaan dan pencarian pertolongan medis penting untuk mengendalikan rabies. Tujuan: Tujuan penelitian ini adalah untuk mengetahui gambaran serta faktor-faktor yang berhubungan dengan perilaku terkait rabies pada pemilik anjing di Provinsi Bali tahun 2025. Metode: Studi cross-sectional menggunakan data primer melalui pengisian kuesioner di empat desa/kelurahan dengan kasus HPR positif berulang. Data kategorik dianalisis secara univariat menggunakan persentase dan bivariat menggunakan uji chi-square. Hasil: Dari 228 sampel, 83,7% pemilik anjing mempunyai perilaku yang baik, sementara 12,7% lainnya kurang baik. Faktor yang berhubungan dengan perilaku kurang baik terkait rabies adalah pendapatan rendah (PR = 2,22; 95% CI = 1,06–4,67), tidak bekerja (PR = 2,39; 95% CI = 1,22–4,67), daerah tempat tinggal di kota (PR = 0,42; 95% CI = 0,20–0,88), rumah sewa/kontrak/milik orang lain (PR = 2,22; 95% CI = 1,14–4,35), jumlah anjing 1 ekor (PR = 2,72; 95% CI = 1,26–5,88), pengetahuan kurang baik terkait rabies (PR = 2,82; 95% CI = 1,30–6,09), dan sikap kurang baik terkait rabies (PR = 2,79; 95% CI = 1,33–5,87). Kesimpulan: Perilaku pemilik anjing di Provinsi Bali secara umum sudah baik, namun upaya promosi dan edukasi rabies harus dilanjutkan dan ditingkatkan supaya pengetahuan yang baik mampu diterjemahkan menjadi perilaku yang baik.

Background: Rabies is a disease that is 99% caused by dog bites and is almost 100% fatal, but it can be prevented by annual dog vaccination and post-bite treatment in humans. Bali Province has the highest number of cases of rabies-transmitting animal (RTA) bites in Indonesia and human rabies deaths are still occurring. Therefore, pet vaccination and health-seeking behavior in dog owners are important for rabies control. Aim: This study aims to describe and determine the factors associated with rabies-related behaviors among dog owners in Bali Province in 2025. Methods: This is a cross-sectional study using primary data collected through questionnaires in two villages and two subdistricts with repeated positive RTA cases. Categorical data were analyzed using percentages for univariate analysis and chi-square for bivariate analysis. Results: Of the 228 samples, 83.7% of dog owners have good rabies-related behaviors, while 12.7% have poor behaviors. Factors associated with poor rabies-related behaviors were low income (PR = 2.22; 95% CI = 1.06–4.67), unemployed (PR = 2.39; 95% CI = 1.22–4.67), urban area of residence (PR = 0.42; 95% CI = 0.20–0.88), home rented/leased/owned by someone else (PR = 2.22; 95% CI = 1.14–4.35), owning 1 dog (PR = 2.72; 95% CI = 1.26–5.88), poor rabies-related knowledge (PR = 2.82; 95% CI = 1.30–6.09), and poor rabies-related attitudes (PR = 2.79; 95% CI = 1.33–5.87). Conclusion: Rabies-related behaviors of dog owners in Bali Province is generally good, but rabies promotion and education efforts must be continued and improved so that good knowledge can be translated into good behaviors.