Latar belakang: Indonesia mencatat 25.639 kasus suspek campak pada 2024 dengan 12,90% terkonfirmasi laboratorium. Cakupan dosis pertama vaksin campak (MCV1) di DKI Jakarta mencapai 98,40% pada 2024, namun provinsi ini melaporkan incidence rate 32,10 per 100.000 penduduk pada 2023. Studi terdahulu menilai faktor risiko campak pada satu tingkat analisis. Penelitian ini menganalisis faktor individu dan kontekstual yang berhubungan dengan kejadian campak terkonfirmasi di DKI Jakarta tahun 2021–2025. Metode: Penelitian cross-sectional ini menganalisis data surveilans campak Dinas Kesehatan Provinsi DKI Jakarta periode Januari 2021–Desember 2025. Subjek adalah kasus suspek campak dengan hasil laboratorium IgM positif atau negatif; kasus tanpa hasil laboratorium dan tanpa data alamat RW atau kelurahan dieksklusi. Variabel individu meliputi usia, jenis kelamin, status vaksinasi, riwayat kontak, riwayat perjalanan, dan pemberian vitamin A. Variabel kontekstual meliputi klasifikasi permukiman RW serta cakupan MCV1, dosis kedua vaksin campak (MCV2), vitamin A, dan kepadatan penduduk kelurahan. Data dianalisis dengan regresi logistik multilevel tiga tingkat, yaitu individu, RW, dan kelurahan, menggunakan adjusted odds ratio (aOR) dan 95% confidence interval (CI). Hasil: Dari 13.545 kasus suspek, 5.797 (42,80%) memenuhi kriteria dan terkelompok dalam 1.980 RW di 270 kelurahan; 1.341 (23,13%) terkonfirmasi laboratorium. Anak usia ≤5 tahun berhubungan dengan campak terkonfirmasi (aOR 1,52; 95% CI 1,31–1,77), demikian pula status tidak divaksinasi (aOR 1,95; 95% CI 1,65–2,30). Setiap peningkatan 10% cakupan MCV1 di kelurahan menurunkan odds campak (aOR 0,53; 95% CI 0,40–0,69), dan setiap peningkatan 10% cakupan vitamin A menurunkan odds (aOR 0,85; 95% CI 0,78–0,93). Intraclass correlation coefficient sebesar 12% pada tingkat kelurahan dan 18% pada tingkat RW menunjukkan variasi geografis yang persisten. Kesimpulan: Kerentanan anak usia dini, status tidak divaksinasi, dan rendahnya cakupan MCV1 serta vitamin A tingkat kelurahan berhubungan dengan campak terkonfirmasi laboratorium di DKI Jakarta. Dinas Kesehatan DKI Jakarta perlu memprioritaskan catch-up vaccination anak ≤5 tahun yang belum divaksinasi dan micro-planning imunisasi di RW rentan.

Background: Indonesia recorded 25,639 suspected measles cases in 2024, with 12.90% laboratory confirmed. First-dose measles vaccine (MCV1) coverage in DKI Jakarta reached 98.40% in 2024, but the province reported an incidence rate of 32.10 per 100,000 population in 2023. Previous studies assessed measles risk factors at a single level of analysis. This study analyzes individual and contextual factors associated with confirmed measles incidence in DKI Jakarta 2021-2025. Methods: This cross-sectional study analyzed measles surveillance data from the Jakarta Provincial Health Office for the period January 2021–December 2025. Subjects were suspected measles cases with positive or negative IgM laboratory results; cases without laboratory results and without RW or sub-district address data were excluded. Individual variables included age, sex, vaccination status, contact history, travel history, and vitamin A administration. Contextual variables included RW organizational classification and MCV1 coverage, second dose of measles vaccine (MCV2), vitamin A, and sub-district population density. Data were analyzed using three-level multilevel logistic regression: individual, RW, and sub-district, using Adjusted Odds Ratio (aOR) and 95% Confidence Interval (CI). Results: Of the 13,545 suspected cases, 5,797 (42.80%) met the criteria and were clustered in 1,980 RWs across 270 sub-districts; 1,341 (23.13%) were laboratory-confirmed. Children aged ≤5 years were associated with confirmed measles (aOR 1.52; 95% CI 1.31–1.77), as was unvaccinated status (aOR 1.95; 95% CI 1.65–2.30). Each 10% increase in MCV1 coverage in the village decreased the odds of measles (aOR 0.53; 95% CI 0.40–0.69), and each 10% increase in vitamin A coverage decreased the odds (aOR 0.85; 95% CI 0.78–0.93). Intraclass correlation coefficients of 12% at the village level and 18% at the neighborhood unit (RW) level indicated persistent geographic variation. Conclusion: Early childhood vulnerability, unvaccinated status, and low levels of MCV1 and vitamin A coverage at the village level were associated with laboratory-confirmed measles in Jakarta. The Jakarta Health Office needs to prioritize catch-up vaccinations for children under 5 years of age who have not yet received micro-planned immunizations in vulnerable neighborhoods (RW).