Pendahuluan: Data menurut Kemenkes RI didapatkan cakupan hasil kegiatan program deteksi dini dari tahun 2007 sampai 2014 baru sekitar 904.099 perempuan (2,45%) yang telah melakukan deteksi dini kanker serviks. Tujuan: Penelitian bertujuan untuk mengetahui hubungan pengetahuan dengan perilaku deteksi dini kanker serviks pada wanita di Kelurahan Kebon Kalapa Kota Bogor. Metode: Analisis data sekunder dari Survei data studi kohor faktor risiko penyakit tidak menular tahun 2011 dengan desain cross-sectional. Sampel penelitian yaitu semua wanita usia 25-65 tahun yang mengikuti survei sebanyak 1226 wanita. Analisis menggunakan regresi logistik. Hasil: wanita yang pernah melakukan deteksi dini kanker serviks di Kelurahan Kebon Kalapa Kota Bogor hanya 6,3% saja dan ada hubungan antara pengetahuan dengan perilaku deteksi dini kanker serviks. Wanita yang pengetahuannya baik tentang kanker serviks berpeluang 2,0 kali untuk melakukan deteksi dini dibandingkan dengan wanita yang pengetahuannya kurang baik (0R 2,0 , 95% CI: 1,2-3,3). Kesimpulan: wanita yang pengetahuannya baik menegenai kanker serviks lebih berpeluang untuk melakukan deteksi dini kanker serviks setelah dikontrol dengan variabel confounding pendidikan. Kata kunci: kanker serviks, deteksi dini kanker serviks, pengetahuan Background: Data obtained by the ministry of health RI, there were only 904.099 women who had cervical cancer screening (2,45%) from year 2007-2014. Objective: This study aimed to analyze the relationship between knowledge with early detection of cervical cancer behavior on woman in Kelurahan Kebon Kalapa Kota Bogor. Methods: An analysis of secondary data from data of kohor study of noncommunicable disease risk factors 2011 with cross sectional design study. A sample of 1226 women qualified into criteria were women aged 25-65 years who participate at the survey. Analysis using logistic regression. Results: The results showed only 6,3% of women in Kelurahan Kebon Kalapa Kota Bogor did screening for cervical cancer and there was a relationship between knowledge with early detection of cervical cancer behavior. Women with good knowledge of cervical cancer were 2,0 more likely to do cervical cancer screening (OR 2,0, 95% CI: 1,2-3,3). Conclusion: Women with good knowledge of cervical cancer were more likely to do cervical cancer screening after being controlled by education as a confounding variable. Keyword: Cervical Cancer, Early Detection of Cervical Cancer, Knowledge