Penelitian ini merupakan penelitian kuantitatif dan kualitatif dengan desainstudi kasus melalui pendekatan analisis sistem (input-process-output) yang bertujuanuntuk menganalisis gambaran kesiapan atau situasi Kantor Kesehatan Pelabuhandalam upaya cegah tangkal Public Health Emergency of International Concern(PHEIC). Populasi penelitian adalah institusi KKP Kelas I Tanjung Priok secaramenyeluruh. Informan penelitian berjumlah 10 orang yang dipilih menggunakanteknik purposive dan snowball sampling. Pengumpulan data dan analisis situasidilakukan dengan mengumpulkan data primer (daftar tilik kajian mandiri dan hasilwawancara mendalam ), serta data sekunder (laporan tahunan KKP Kelas I TanjungPriok Tahun 2014-2016). Dengan waktu penelitian pada bulan April-Juni 2017.Tingkat kepatuhan (compliance rate) KKP Kelas I Tanjung Priok terhadap standardinilai sangat baik (CR= 95,86%). Terdapat 8 item yang tidak memenuhi standarantara lain: speed boat quarantine, motoris speed boat karantina yang memilikisertifikat ANT V (Ahli Nautica Tingkat 5), tenaga psikolog, petugas penata refraksi,petugas penata audiometri, dan petugas penata spirometri, dan hemocytometer.Kegiatan kekarantinaan dan surveilans epidemiologi dapat 100 % dilaksanakan.Rekomendasi yang diberikan terfokus pada pengadaan sarana dan prasarana sertaSDM yang dibutuhkan dan supervisi kerja petugas KKP dalam upaya cegah tangkalPHEIC.Kata kunci:Kantor Kesehatan Pelabuhan, PHEIC, pintu masuk negara, surveilans epidemiologi,karantina kesehatan

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This research is an analytical study of Public Health Emergency ofInternational Concern Preparedness in Port Health Office using quantitative anqualitative approaches. The purpose of this study is to assess Public HealthEmergency of International Concern Preparedness of Tanjung Priok Port HealthOffice in 2017 based on IHR (2005) and Indonesian quarantine regulation.Population of this study is Tanjung Priok Port Health Office in general. Ten officersare chosen with purposive and snowball samping to be this study informants. Thedata were collected from self-administered PHEIC preparedness assessment filled byinstitutional representative and in-depth interview results (primary data), as well as2014-2016 Tanjung Priok Port Health Office Yearly Reports (secondary data). Thisstudy was conducted on April-June of 2017. Complience rate in Tanjung Priok PortHealth Office is rated excellence (CR=95,86%), although there are 8 items that donot meet the PHEIC preparedness standard, such as quarantine speedboat; quarantinespeedboat motorist with ANT-V sertificate; psychologist; refraction, audiometry, andspirometry experts; and hemocytometer. Quarantine and epidemiologic surveillanceactivities in port of entry have been done 100 %. The researcher suggests that thereshould be an improvement in Port Health Office facilities and human resourcesneeded for PHEIC preparedness.Key words:Port Health Office, PHEIC, port of entry, epidemiologic surveillance, quarantine.