WHO memperkirakan terdapat 8 juta penderita Down syndrome di dunia Penyebab yang spesifik belum diketahui, tapi kehamilan oleh ibu yang berusia diatas 35 tahun beresiko tinggi memiliki anak down syndrom. Pada ibu yang berusia lebih dari 35 tahun, insidensi meningkat sampai 1 dari 300 kelahiran. Sedangkan pada ibu usia di atas 40 tahun, insidensi meningkat secara drastis mencapai 1 dari 10 kelahiran

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WHO estimates that there are 8 million people with Down syndrome in the world he specific cause is not yet known, but pregnancy by mothers over the age 35 years of high risk of having Down syndrome children. In mothers over 35 years of age, the incidence increases to 1 in 300 births. Meanwhile, for mothers over 40 years of age, the incidence increases drastically, reaching 1 in 10 births. This study aims to determine the relationship between maternal age at pregnancy and the incidence of Down syndrome in children aged 0-59 months in Indonesia based on 2018 Riskesdas data. t is necessary to educate productive women about the risks of pregnancy at old age