Tesis ini membahas hubungan konsentrasi paparan PM2,5 dan kadar MDA sebagai biomarker stres oksidatif di lingkungan sebuah pabrik semen. Penelitian ini adalah penelitian kuantitatif dengan desain cross-sectional yang dilakukan pada Mei-Juni 2024. Hasil penelitian bahwa konsentrasi PM2,5 dari 10 titik seluruhnya melebihi baku mutu; hasil pemeriksaan kadar MDA urin bervariasi; tidak ada hubungan yang signifikan antara paparan konsentrasi PM2,5 dengan kadar MDA urin; tidak ada hubungan yang signifikan antara karakteristik inidividu dengan kadar MDA urin; namun terdapat hubungan signifikan antara konsentrasi PM2,5 dan radius dengan p value 0,000; terdapat hubungan signifikan antara konsentrasi PM2,5 dan waktu sampling dengan p value 0,000; dan terdapat hubungan yang signifikan antara kadar MDA dan radius dengan p value 0,000. Kesimpulan penelitian menunjukkan tidak adanya hubungan antara paparan PM2,5 dengan kadar MDA, tidak ada hubungan antara karakteristik individu dengan kadar MDA.
This thesis discusses the relationship between PM2.5 exposure concentrations and MDA levels as biomarkers of oxidative stress in the environment of a cement factory. This research is a quantitative study with a cross-sectional design conducted in May-June 2024. The results of the research show that the PM2.5 concentration from all 10 points exceeds the quality standard; urine MDA level examination results vary; there was no significant relationship between exposure to PM2.5 concentrations and urinary MDA levels; there was no significant relationship between individual characteristics and urinary MDA levels; However, there is a significant relationship between PM2..5 concentration and radius with a p value of 0.000; there is a significant relationship between PM2.5 concentration and sampling time with a p value of 0.000; and there is a significant relationship between MDA levels and radius with a p value of 0.000. The research conclusion shows that there is no relationship between PM2.5 exposure and MDA levels, there is no relationship between individual characteristics and MDA levels.
LULU RAKHMATSANI-Tesis-FKM-Full Text-2024.pdf ::