Petugas tempat pengolahan sampah berbasis reuse, reduce, dan recycle (TPS 3R) merupakan kelompok pekerja yang berisiko tinggi mengalami penyakit akibat kerja seperti diare karena sering berkontak langsung dengan sampah. Penelitian ini bertujuan untuk mengetahui hubungan antara karakteristik individu, personal hygiene, dan kondisi lingkungan terhadap kejadian diare pada petugas TPS 3R di Provinsi DKI Jakarta. Desain penelitian yang digunakan adalah potong lintang (cross-sectional) dengan pendekatan kuantitatif dan melibatkan 62 responden dari 12 lokasi TPS 3R. Data dikumpulkan melalui kuesioner dan observasi, lalu dianalisis menggunakan uji chi-square. Hasil penelitian menunjukkan bahwa masa kerja (p=0,033; OR=5,077; 95% CI: 1,138–22,650), penggunaan alat pelindung diri (APD) (p=0,004; OR=0,150; 95% CI: 0,042–0,541), dan keberadaan vektor penular penyakit (p=0,038; OR=3,600; 95% CI: 1,075–12,059) memiliki hubungan yang signifikan dengan kejadian diare. Sementara itu, variabel usia, jenis kelamin, pendidikan terakhir, serta beberapa indikator personal hygiene dan kondisi lingkungan tidak menunjukkan hubungan yang signifikan. Temuan ini menunjukkan bahwa penguatan perilaku penggunaan APD dan pengendalian vektor menjadi langkah penting dalam upaya pencegahan diare pada petugas TPS 3R.

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Waste management facility based on reuse, reduce, and recycle principles or tempat pengolahan sampah reuse, reduce, and recylce (TPS 3R) workers are a high-risk occupational group for work-related diseases such as diarrhea due to frequent direct contact with waste. This study aims to examine the relationship between individual characteristics, personal hygiene, and environmental conditions with the incidence of diarrhea among TPS 3R workers in DKI Jakarta Province. A cross-sectional quantitative design was employed involving 62 respondents from 12 TPS 3R sites. Data were collected through questionnaires and observations and analyzed using chi-square tests. The results showed significant associations between diarrhea incidence and work duration (p=0.033; OR=5.077; 95% CI: 1.138–22.650), use of personal protective equipment (PPE) (p=0.004; OR=0.150; 95% CI: 0.042–0.541), and the presence of disease vectors (p=0.038; OR=3.600; 95% CI: 1.075–12.059). Meanwhile, variables such as age, gender, education level, and several indicators of personal hygiene and environmental conditions showed no significant associations. These findings highlight the importance of promoting protective equipment usage and vector control as key measures to prevent diarrhea among TPS 3R workers.