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ABSTRAK Nama : Leni Susanti Rusli Program Studi : Magister Epidemilogi Judul : Hipertensi Dan Penyakit Jantung Koroner Pada Penduduk Usia 40 Tahun Atau Lebih Di Indonesia Tahun 2017 Pembimbing : Prof.Dr.Nasrin Kodim,MPH Penyakit jantung koroner menjadi masalah kesehatan masyarakat karena penyebab kematian tertinggi akibat penyakit kardiovaskular. Salah satu faktor risiko PJK adalah hipertensi. Prevalensi PJK dan hipertensi di Indonesia Tahun 2013 sekitar 1,5% dan 25,8%. Tujuan penelitian ini adalah mengetahui hubungan hipertensi dengan kejadian PJK pada penduduk usia 40 tahun atau lebih di Indonesia. Desain Penelitian ini adalah studi cross sectional dengan menggunakan data sekunder dari hasil pemeriksaan kesehatan Jemaah Haji Indonesia Tahun 2017. Analisis data yang digunakan adalah Regresi Logistik. Hasil analisis menemukan bahwa Penduduk usia 40 tahun atau lebih yang hipertensi berisiko 1,342 kali (95% CI 1,048 – 1,238) untuk mengalami PJK dibandingkan dengan yang tidak hipertensi setelah dikontrol oleh kolesterol. Penduduk dewasa dapat menerapakan pola makan sehat dan rutin melakukan pemerikaan tekanan darah serta kolesterol untuk mencegah hipertensi dan PJK. Kata kunci: PJK, hipertensi, kolesterol
ABSTRACT Name : Leni Susanti Rusli Study Program : Master of Epidemiology Title : Controlled Hypertension And Coronary Heart Disease In Population Age 40 Years Or More In Indonesia Year 2017 Counsellor : Prof.Dr.dr. Nasrin Kodim, MPH Coronary heart disease is a public health problem because of the highest cause of death from cardiovascular disease. One of the risk factors of CHD is hypertension. Prevalence of CHD and hypertension in Indonesia In 2013 about 1.5% and 25.8%. The purpose of this study was to determine the relationship of hypertension with CHD events in the age of 40 years or more in Indonesia. Design This study is a cross sectional study using secondary data from the results of health examination Hajj Pilgrim Indonesia 2017. Data analysis used is logistic regression. The results of the analysis found that people aged 40 years or older who had hypertension at risk 1,342 times (95% CI 1.048 - 1.238) to experience CHD compared with non-hypertensive after cholesterol controlled. Adult population can apply a healthy diet and routinely perform blood pressure and cholesterol to prevent hypertension and CHD. Key words: CHD, Hypertension,Cholesterol
Coronary Heart Disease (CHD) remains a major cause of morbidity and mortality in women in Indonesia. The global epidemic of obesity contributes to the increase of cardiovascular events. In Indonesia, there have not been many studies evaluate the association between abdominal obesity and CHD in women. Therefore, this study aims to determine the association between abdominal obesity and CHD in women aged 25-65 years in Bogor. This retrospective cohort study involves 2.451 respondents of FRPTM Cohort Study who met the inclusion and exclusion criteria with an observation period of 6 years. The main independent variable of this study was abdominal obesity based on Waist-to-Height-Ratio (WHtR), while outcome of the interest was CHD based on the results of interview and/or ECG results. Cox regression analysis was performed to estimated Hazard Ratio (HR) with a 95% Confidence Interval (95% CI). The results showed that the incidence rate of CHD in women was 19 per 1.000 person-years. Women with abdominal obesity were 1,38 times (95% CI 1,01-1,89) more likely to have CHD than those without abdominal obesity after adjustment for age, hypertension, and menopause status. Early detection of CHD risk factor, especially abdominal obesity, is important, so that prevention and lifestyle modification can be implemented immediately.
Latar belakang: Diabetes melitus merupakan penyakit tidak menular yang menjadi prioritas global, penyebab utama kematian dan kecacatan. Indonesia menempati peringkat ketiga di dunia dengan 73,7% kasus DM yang tidak terdiagnosis. Prevalensi DM di Indonesia terus mengalami peningkatan setiap tahunnya. Obesitas sentral dikaitkan dengan peningkatan risiko diabetes melitus. Beberapa penelitian telah menunjukkan adanya hubungan antara obesitas sentral dengan kejadian diabetes melitus. Namun, penentuan diagnosis DM hanya didasarkan pada pemeriksaan glukosa darah sewaktu, tanpa disertai informasi mengenai gejala dan Riwayat DM sebelumnya. Penelitian ini bertujuan untuk mengetahui hubungan obesitas sentral dengan diabetes melitus yang baru didiagnosis berdasarkan pemeriksaan kadar glukosa darah atau HbA1c pada penduduk usia ≥15 tahun di Indonesia.
Metode: Penelitian ini menggunakan data sekunder Survei Kesehatan Indonesia (SKI) tahun 2023. Jumlah sampel yang dianalisis sebanyak 25.494. Analisis multivariat menggunakan cox regression untuk mengetahui hubungan antara obesitas sentral dengan kejadian diabetes melitus yang baru didiagnosis berdasarkan pemeriksaan kadar glukosa darah atau HbA1c pada penduduk usia ≥15 tahun di Indonesia setelah dikontrol oleh variabel kovariat.
Hasil: Prevalensi diabetes melitus yang baru didiagnosis sebesar 16,0%. Obesitas sentral meningkatkan risiko diabetes melitus sebesar 1,6 kali (PR: 1,6; 95% CI: 1,53–1,76) setelah dikontrol usia, jenis kelamin, aktivitas fisik, hipertensi, dan dislipidemia.
Kesimpulan: Penduduk usia ≥15 tahun di Indonesia dengan obesitas sentral memiliki risiko 1,6 kali lebih besar untuk menderita diabetes melitus dibandingkan penduduk usia ≥15 tahun tanpa obesitas sentral setelah dikontrol oleh usia, jenis kelamin, aktivitas fisik, hipertensi dan dislipidemia. Temuan ini menekankan pentingnya modifikasi gaya hidup melalui pola makan sehat, aktivitas fisik rutin, serta deteksi dini sebagai upaya pencegahan dan pengendalian DM.
Coronary Heart Disease (CHD) is a leading cause of death in the cardiovascular group. Obesity could increase a person's risk of progression from prediabetes to type 2 DM and increase the risk of cardiovascular disease. Prediabetes with obesity increases the risk of CHD events based on Cardiometabolic Disease Staging (CMDS). This study was used a retrospective cohort study design using secondary data on NCD Risk Factor Cohort Study in 2011-2018. The sample was 493 obese adult respondents in population of NCD Risk Factor Cohort Study whom met this study inclusion and exclusion criteria. The results of multivariate analysis using cox regression after being controlled by age and duration of obesity found that prediabetes had HR = 0.80 (95% CI: 0.462- 1.387), p = 0.429 which means the relationship between prediabetes with CHD events in obese adult respondents was not statistically significant.
Background: Coronary heart disease is a non-communicable disease. Risk faktors for coronary heart disease include hypertension, smoking, high cholesterol, obesity, and low consumption of fruits and vegetables. According to Riskesdas data in 2013, the prevalence of coronary heart disease with a doctor's diagnosis was 0.5%. Meanwhile, in 2018 the prevalence of coronary heart disease with a doctor's diagnosis was 1.5%. Then there is an increase in respondents who suffer from coronary heart disease. Coronary heart disease is caused by the buildup of plaque on the walls of the arteries that supply blood to the heart and other parts of the body. The plaque consists of deposits of cholesterol and other substances in the arteries. Plaque buildup causes the inside of the arteries to narrow over time, which can partially or completely block blood flow. The purpose of this study was to determine the relationship between the combined effect of hypertension and obesity with the incidence of coronary heart disease Methods: This analysis uses univariate analysis to determine the proportion of research variables, bivariate analysis to determine the relationship between variables, stratification analysis to determine the presence of confounding and modification effects. Multivariate analysis to determine the final model. This study used a cross sectional design. Results: found coronary heart disease variables 1.44%, hypertension and obesity 9.77%, hypertension and not obesity 9.64%, not hypertension and obesity 22.04%, not hypertension and not obesity 58.55%. And the relationship of hypertension and obesity to coronary heart disease after being controlled by age and sex variables. Conclusion: The relationship of the combined effect of hypertension and obesity with the incidence of coronary heart disease after being controlled by age and sex variables
