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Coronary Heart Disease (CHD) remains a major cause of morbidity and mortality in women in Indonesia. The global epidemic of obesity contributes to the increase of cardiovascular events. In Indonesia, there have not been many studies evaluate the association between abdominal obesity and CHD in women. Therefore, this study aims to determine the association between abdominal obesity and CHD in women aged 25-65 years in Bogor. This retrospective cohort study involves 2.451 respondents of FRPTM Cohort Study who met the inclusion and exclusion criteria with an observation period of 6 years. The main independent variable of this study was abdominal obesity based on Waist-to-Height-Ratio (WHtR), while outcome of the interest was CHD based on the results of interview and/or ECG results. Cox regression analysis was performed to estimated Hazard Ratio (HR) with a 95% Confidence Interval (95% CI). The results showed that the incidence rate of CHD in women was 19 per 1.000 person-years. Women with abdominal obesity were 1,38 times (95% CI 1,01-1,89) more likely to have CHD than those without abdominal obesity after adjustment for age, hypertension, and menopause status. Early detection of CHD risk factor, especially abdominal obesity, is important, so that prevention and lifestyle modification can be implemented immediately.
Coronary Heart Disease (CHD) is a leading cause of death in the cardiovascular group. Obesity could increase a person's risk of progression from prediabetes to type 2 DM and increase the risk of cardiovascular disease. Prediabetes with obesity increases the risk of CHD events based on Cardiometabolic Disease Staging (CMDS). This study was used a retrospective cohort study design using secondary data on NCD Risk Factor Cohort Study in 2011-2018. The sample was 493 obese adult respondents in population of NCD Risk Factor Cohort Study whom met this study inclusion and exclusion criteria. The results of multivariate analysis using cox regression after being controlled by age and duration of obesity found that prediabetes had HR = 0.80 (95% CI: 0.462- 1.387), p = 0.429 which means the relationship between prediabetes with CHD events in obese adult respondents was not statistically significant.
Background: Coronary heart disease is a non-communicable disease. Risk faktors for coronary heart disease include hypertension, smoking, high cholesterol, obesity, and low consumption of fruits and vegetables. According to Riskesdas data in 2013, the prevalence of coronary heart disease with a doctor's diagnosis was 0.5%. Meanwhile, in 2018 the prevalence of coronary heart disease with a doctor's diagnosis was 1.5%. Then there is an increase in respondents who suffer from coronary heart disease. Coronary heart disease is caused by the buildup of plaque on the walls of the arteries that supply blood to the heart and other parts of the body. The plaque consists of deposits of cholesterol and other substances in the arteries. Plaque buildup causes the inside of the arteries to narrow over time, which can partially or completely block blood flow. The purpose of this study was to determine the relationship between the combined effect of hypertension and obesity with the incidence of coronary heart disease Methods: This analysis uses univariate analysis to determine the proportion of research variables, bivariate analysis to determine the relationship between variables, stratification analysis to determine the presence of confounding and modification effects. Multivariate analysis to determine the final model. This study used a cross sectional design. Results: found coronary heart disease variables 1.44%, hypertension and obesity 9.77%, hypertension and not obesity 9.64%, not hypertension and obesity 22.04%, not hypertension and not obesity 58.55%. And the relationship of hypertension and obesity to coronary heart disease after being controlled by age and sex variables. Conclusion: The relationship of the combined effect of hypertension and obesity with the incidence of coronary heart disease after being controlled by age and sex variables
Penyakit jantung koroner merupakan penyebab utama kematian di dunia yang akan terus meningkat dan menjadi pandemi tanpa memandang batas negara. Setiap tahun di dunia sebanyak 3.8 juta laki-laki dan 3.4 jiwa wanita meninggal karena penyakit jantung koroner. Perubahan daya hidup, peningkatan usia harapan hidup dan urbanisasi mendorong timbulnya abnormalitas metabolisme seperti obesitas, dislipidemia, resistensi insulin dan hipertensi. Kumpulan abnormalitas metablik ini disebut dengan sindroma metabolik pada akhirnya akan meningkatkan kemungkinan menderita penyakit jantung koroner tiga kali lipat Tujuan penelitian ini adalah untuk mengetahuinya hubungan sindroma metabolik dengan penyakit jantung koroner di RS. DR. M. Djamil Padang Tahun 2008 setelah dikontrol dengan variabel umur, jenis kelamin, pendidikan, pekerjaan, kebiasaan merokok, kebiasaan minum alkohol dan aktivitas fisik. Desain penelitian ini adalah kasus kontrol. Kasus adalah penderita baru penyakit jantung koroner berdasarkan pemeriksaan EKG oleh dokter, penyakit tersebut baru terdiagnosis pada Bulan Januari sampai Mei 2008. Kontrol adalah semua pengunjung ang dinyatakan sebagai bukan penderita penyakit jantung koroner, pada Bulan Januari sampai Mei 2008 berdasarkan pemeriksaan EKG oleh dokter. Sindroma Metabolik menurut AHA/NHLBI 2005 ditegakkan diagnosis bila terdapat empat kriteria dibawah ini: tekanan darah > 130/85 mmHg, kadar trigliserida darah >150mg/dl, kolesterol HDL pada laki-laki < 40 mg/dl dan wanita < 50 mg/dl dan kadar gula darah puasa > 100mg/dl Telah dilakukan panelitian terhadap 300 orang responden terdiri dari 150 pada kelompok kasus dan 150 pada kelompok kontrol. Hasil analisis multivariat didapatkan kejadian penyakit jantung koroner (PJK) berisiko 4,67 kali lebih besar pada orang yang mengalami sindroma metabolik dibandingkan dengan orang yang tidak mengalami sindroma metabolik setelah dikontrol dengan variabel jenis kelamin (95% CI:1,20-18,06). Pada hasil penelitian ini dapat disimpulkan bahwa ada hubungan antara sindroma metabolik dengan kejadian penyakit jantung koroner di RS. DR. M. Djamil Padang tahun 2008.
ABSTRAK Nama : Leni Susanti Rusli Program Studi : Magister Epidemilogi Judul : Hipertensi Dan Penyakit Jantung Koroner Pada Penduduk Usia 40 Tahun Atau Lebih Di Indonesia Tahun 2017 Pembimbing : Prof.Dr.Nasrin Kodim,MPH Penyakit jantung koroner menjadi masalah kesehatan masyarakat karena penyebab kematian tertinggi akibat penyakit kardiovaskular. Salah satu faktor risiko PJK adalah hipertensi. Prevalensi PJK dan hipertensi di Indonesia Tahun 2013 sekitar 1,5% dan 25,8%. Tujuan penelitian ini adalah mengetahui hubungan hipertensi dengan kejadian PJK pada penduduk usia 40 tahun atau lebih di Indonesia. Desain Penelitian ini adalah studi cross sectional dengan menggunakan data sekunder dari hasil pemeriksaan kesehatan Jemaah Haji Indonesia Tahun 2017. Analisis data yang digunakan adalah Regresi Logistik. Hasil analisis menemukan bahwa Penduduk usia 40 tahun atau lebih yang hipertensi berisiko 1,342 kali (95% CI 1,048 – 1,238) untuk mengalami PJK dibandingkan dengan yang tidak hipertensi setelah dikontrol oleh kolesterol. Penduduk dewasa dapat menerapakan pola makan sehat dan rutin melakukan pemerikaan tekanan darah serta kolesterol untuk mencegah hipertensi dan PJK. Kata kunci: PJK, hipertensi, kolesterol
ABSTRACT Name : Leni Susanti Rusli Study Program : Master of Epidemiology Title : Controlled Hypertension And Coronary Heart Disease In Population Age 40 Years Or More In Indonesia Year 2017 Counsellor : Prof.Dr.dr. Nasrin Kodim, MPH Coronary heart disease is a public health problem because of the highest cause of death from cardiovascular disease. One of the risk factors of CHD is hypertension. Prevalence of CHD and hypertension in Indonesia In 2013 about 1.5% and 25.8%. The purpose of this study was to determine the relationship of hypertension with CHD events in the age of 40 years or more in Indonesia. Design This study is a cross sectional study using secondary data from the results of health examination Hajj Pilgrim Indonesia 2017. Data analysis used is logistic regression. The results of the analysis found that people aged 40 years or older who had hypertension at risk 1,342 times (95% CI 1.048 - 1.238) to experience CHD compared with non-hypertensive after cholesterol controlled. Adult population can apply a healthy diet and routinely perform blood pressure and cholesterol to prevent hypertension and CHD. Key words: CHD, Hypertension,Cholesterol
Cardiovascular disease is the number one cause of death from NCD, according to WHO in 2015 deaths from cardiovascular disease represent 31 17 million of total all deaths globally and 7.4 million are caused by CHD. In Indonesia, the increase in morbidity and mortality due to NCD has the greatest contribution from cardiovascular disease, where CHD is the highest prevalence of cardiovascular disease. CHD is caused by modifiable risk factors and unmodifiable risk factors. The prevalence of CHD can be controlled if risk factors can be controlled, considering there are risk factors from CHD that can be modified. DKI Jakarta becomes the second highest area with the prevalence of CHD in Indonesia. However, the relation between modifiable risk factors and CHD and the most dominant risk factors among them remains unknown in DKI Jakarta. The aim of this study is to know how the relation between some risk factors that can be modified with CHD in DKI Jakarta and find the most dominant risk factor associated with PJK by doing further analysis of data Posbindu PTM 2015 2018. This study used cross sectional design and the analysis was done until multivariate analysis stage using logistic regression test. From 30.459 respondents aged ge 15 years, the prevalence of CHD was 3.4. Smoking behavior p value 0,000 OR 6,53 95 CI 4,826 ndash 8,838 , physical inactivity p value 0,045 OR 0,745 95 CI 0,558 ndash 0,993, alcohol consumption p value 0,000 OR 3057,076 95 CI 1786,92-5230,06, diabetes mellitus, value 0,000 OR 0,161 95 CI 0,161 ndash 0,508, and hypertension p value 0,000 OR 0,284 95 CI 0,284 ndash 0,526 are factors that have significant relations with CHD. The dominant risk factor of CHD in DKI Jakarta is alcohol consumption. Promotive and preventive efforts are expected to be intensified in order to reduce the incidence of CHD and the need for further surveys related to alcohol consumption because alcohol consumption is the dominant factor in this study and according to the literature it has great effect on heart function damage.
