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Industri farmasi merupakan industri yang memiliki risko kebakaran dan ledakan yang sangat besar karena penanganan beragam bahan kimia cair, padatan, dan gas yang mudah terbakar serta bahan kimia berbahaya lainnya. Tujuan umum dari penelitian ini adalah untuk mengklasifikasikan area berbahaya berdasarkan standar IEC 60079-10-2 serta menganalisis tingkat risiko kebakaran dan ledakan debu dalam proses granulasi pada fasilitas Non Betalactam (Multi Product Facility). Penelitian ini merupakan penelitian deskriptif semi kuantitatif yang bertujuan untuk mengklasifikasikan area berbahaya pada proses granulasi berdasarkan standar IEC 60079-10-2 dan menentukan tingkat risiko kebakaran dan ledakan debu dalam tahapan pencampuran (mixing) dengan menggunakan metode Dow’s Fire Explosion Index. Populasi ini melibatkan semua bahan kimia berbahaya dan peralatan yang digunakan pada proses pembuatan obat di PT. X. Combustible dust yang digunakan dalam proses granulasi pada fasilitas Non Betalactam Facility (Multi Product Facility) berupa bahan aktif farmasi dan eksipien, seperti methyldopa hydrate, paracetamol, loperamide hydrochloride, diazepam, domperidone, prednisolone micronised, magnesium stearate. polyvidone 30, sodium starch glycolate, dan amylum maydis. Minimum Ignition Energy (MIE) yang dimiliki oleh semua bahan aktif berbeda-beda nilainya sesuai hasil uji laboratorium eksternal dengan nilai yang paling sensitif terhadap penyalaan, yaitu diazepam, methyldopa hydrate, loperamide hydrochloride, domperidone dan prednisolone micronised yang mempunyai nilai MIE 1-3 mj yang dapat menyebabkan ledakan kuat hingga sangat kuat jika memenuhi konsentrasi Minimum Explosive Concentration (MEC). Sehubungan dengan hal itu, sebelum menentukan klasifikasi area berbahaya, sangat penting untuk mengidentifikasi sumber penyalaan di area proses tersebut. Adapun sumber penyalaan tersebut bersumber dari peralatan listrik, listrik statis, dan friction/mechanical spark. Klasifikasi area berbahaya dengan kategori zona dalam proses granulasi pada fasilitas Non Betalactam (Multi Product Facility) terdiri dari zona 20 di setiap dalam chamber/container peralatan, zona 21 di setiap bukaan hopper/charging unit, tempat perilisan debu dengan radius satu meter dan zona 22 di luar zona 21 di dalam ruangan proses granulasi. Tingkat risiko kebakaran dan ledakan debu pada proses granulasi (mixing) dengan menggunakan metode granulasi basah (hybrid mixture) berdasarkan metode Dow’s Fire and Explosion Index adalah risiko sedang (moderate) dengan total skor 95,1762 dengan radius paparannya sebesar 29,010 meter dan estimasi kerugiannya mencapai Rp 1.467.276.735.672. Oleh karenanya, sangat penting untuk melakukan mitigasi risiko sehingga risiko kebakaran dan ledakan debu di area proses ini berada pada risiko yang rendah.
The pharmaceutical industry is an industry that has a very large risk of fire and explosion due to the handling of a variety of flammable liquid, solid and gaseous chemicals as well as other hazardous chemicals. The general objective of this study is to classify hazardous areas based on IEC 60079-10-2 standards and to analyze the risk level of fire and dust explosion in the granulation process at the Non Betalactam facility (Multi Product Facility). This research is a semi-quantitative descriptive study that aims to classify hazardous areas in the granulation process based on IEC 60079-10-2 standards and determine the risk level of fire and dust explosion in the mixing stage using the Dow's Fire Explosion Index method. This population includes all hazardous chemicals and equipment used in the drug manufacturing process at PT. X. Combustible dust used in the granulation process at the Non Betalactam Facility (Multi Product Facility) is in the form of active pharmaceutical ingredients and excipients, such as methyldopa hydrate, paracetamol, loperamide hydrochloride, diazepam, domperidone, micronised prednisolone, magnesium stearate. polyvidone 30, sodium starch glycolate, and amylum maydis. The Minimum Ignition Energy (MIE) that all active ingredients have a different value according to the results of external laboratory tests with values that are most sensitive to ignition, namely diazepam, methyldopa hydrate, loperamide hydrochloride, domperidone and micronised prednisolone which have an MIE value of 1-3 mj which can cause a strong to very strong explosion if it meets the Minimum Explosive Concentration (MEC) concentration. In this regard, before determining the classification of a hazardous area, it is very important to identify the source of ignition in the process area. The ignition sources come from electrical equipment, static electricity, and friction/mechanical spark. Classification of hazardous areas with the category of zones in the granulation process at Non Betalactam facilities (Multi Product Facility) consists of zone 20 in each equipment chamber/container, zone 21 in each opening of the hopper/charging unit, a dust release area with a radius of one meter and zone 22 outside zone 21 in the granulation process room. The risk level of fire and dust explosion in the granulation process (mixing) using the wet granulation method (hybrid mixture) based on the Dow's Fire and Explosion Index method is moderate risk with a total score of 95.1762 with an exposure radius of 29.010 meters and an estimated loss of IDR 1,467. 276,735,672. Therefore, it is very important to carry out risk mitigation so that the risk of fire and dust explosion in this process area is at a low risk.
The petrochemical industry is a high-risk sector for fire and explosion hazards due to the involvement of flammable and toxic substances, as well as operating conditions at high temperatures and pressures. This study is a semi-quantitative descriptive research aimed at classifying hazardous areas in the production process based on the API RP 500 standard and determining the level of fire and explosion risk in the ammonia gas production process using the Dow’s Fire and Explosion Index (DF&EI) method. The methodological approach includes the identification of hazardous chemicals, hazard level assessment using DF&EI, analysis of loss estimation and exposure radius, and assessment of ammonia gas dispersion and process explosion using the ALOHA software. The analysis results show that Plant 1A has a DF&EI index categorized as severe, with an exposure radius of 223.78 meters and an actual MPPD of IDR 154 billion in the ammonia converter unit, and categorized as light, with an exposure radius of 45.78 meters and an actual MPPD of IDR 47 billion in the urea reactor unit. The hazardous area classification indicates the presence of Class I, Division 2 classified zones in several parts of the production process close to the ammonia vapor and natural gas release sources. The worst-case scenario shows a significant impact due to an explosion from the ammonia converter unit with a blast radius of up to 269 meters causing window glass breakage, and ammonia gas dispersion from the urea reactor spreading up to 10 kilometers, potentially causing respiratory issues.
The use of biogas in supporting development activities has the risk of fire and explosion due to the structure of its constituent composition. The accident rate due to biogas in Europe was recorded quite significantly in the period 2007 2014, there are 144 cases of which 17 fatalities. This study aims to analyze the risk of fire and explosion at the biogas plant at PT X with a quantitative approach through analysis of the likelihood, consequence, and estimating the level of risk of fire and explosion at the biogas plant at PT X. Analysis of the possibility of fire and explosion risk using the Event Tree Analysis method (ETA) and for the analysis of consequences using the software Areal Locations of Hazardous Atmosphere (ALOHA) v.5.4.7. The result of this research is that there is a scenario of gas leakage from the pipeline during biogas operation which has an impact on jet fire, flash fire and explosion with a probability of 1.08, E-06 for jet fire, 1.30, E-05 for flash fire, and 8, 64,E-06 for explosion. The impact of the jet fire was 20 meters, the vapor cloud reached 63 meters, the explosion was 26 meters, and the toxic threat zone was less than 10 meters. The individual risk for a job with a working time of 10 hours such as a biogas operational assistant is 6.935 x 10-9 and for a job with a working time of 12 hours such as a biodigester, gas engine and security operator is 8.322 x 10-9. Total Potential Loss of Life (PLL) is 1,304 x 10-7. Thus, individual and social risks are still at an acceptable level. Recommendations that can be given are implementing risk-based preventive controls, evaluating fire protection systems, developing crisis management and emergency response programs both in terms of human resources and facilities
Introduction: Hydrocarbons are flammable materials can cause major accidents and explosions at offshore platform hydrocarbon processing. Fires and explosions on offshore platforms are relatively rare accidents but can have unforeseen consequences that can have a significant impact on fatality and loss of assets. Methods: Descriptive method with quantitative design from secondary data in 2020 (cross sectional) and literature study without intervention on the research object (non-experimental) using software (PHAST) to evaluate the consequences of fire and explosion models. Frequency analysis with fault tree and event tree analysis methods, to analyse the possibility of overpressure and major accidents events on offshore platforms hydrocarbon processing facilities which are Major Hazard Plants. Result: The highest risk level for the personnel fatality working on the offshore platform is in the ALARP Region level from the largest contributor to the flash fire scenario with the number of fatalities as many as 10 peoples and the frequency value of 3.26E-08/year means 1 out of 30,674,847 flash fire scenario opportunities in 1 year can occur to cause fatality of 10 people, while the risk to assets is in an acceptable risk level from the largest contributor to the jet fire scenario with loss of assets 40,590,800.00 and the highest frequency value is 6.31E-08/year) means that 1 in 15,847,861 opportunities of a jet fire scenario in 1 year can occur to cause asset loss of $ 40,590,800 from fires and explosions in overpressure scenarios that have the potential to occur on the new offshore platform taking into account some of the safety systems that have been defined in the design. Conclusion: There is no need for additional mitigation because the safety system that has been determined in the design is sufficient to prevent major accidents that can occur so that the new offshore platform is declared safe to operate.
The focus of this thesis discuses about risk factors and the impact of fires and explosions that can occur from the operation of boilers in the PT X Food Industry. This research is a semi quantitative research using Dows Fire and Explosion Index calculation method and the ALOHA software version 5.4.7 which is superimposed with MARPLOT. The results of the study obtained a value of 111,62 with the classification of the risk level of Boiler fire and explosion hazard in the Intermediate category. The population affected by the fire and explosion was 615 workers with an estimated loss Rp. 879.872.821.672. PT. X can reduce the value of losses and prevent fires and explosions through the provision of adequate active and passive fire protection facilities, updating emergency response prosedures, simulatin, personnel training and upgrading the Boiler System to Automatic Boiler
Introduction: Major fire accident involving static electricity still become serious latent problem (1), this similar to PT XYZ which still experience serious fire incident caused by static electric. This study intend to do the analysis of the adequacy of the protection to fire and explosion caused by electric static at hazardous process at paint production. Methode: This analysis is using bow tie analysis and risk assasment matrix, Bow Tie analysis describe and visualize the correlation between what caused rsik, top event, and control that used to anticipate the incident happened and also mitigation barrier that can prevent from further escalation, then risk assasment matrix give semiquantitative risk calculation to reflect the level of risk. From this determination than we decide recommended control base on best practice and standard which is relevant. Results: From this study we found that at paint manufacture PT XYZ only 22% of protection is adequate to prevent from electrostatic, than 7% of threat still categorized very high , 40% is high risk , and 31% is moderate risk. Base on best practice and literature study than we recommend some of action that need to be taken to improve the barrier. Conclution: The recommendation basicly is to improve the visibility of grounding performance using lam indicator, improve visibility of flammable atmosphere using LEL detection , to reduce electrostatic discharge during process by control the liquid flow, to improve charge relaxation by selecting the tools properly, and to prevent fire during cleaning by inerting and reduce the solvent mist, also to increase the conductivity of non conductive solvent by adding conductivity agent