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Dengan semakin meningkatnya usia harapan hidup di Indonesia maka populasi usia Ianjut pun semakin bertambah. Menjalani masa tua dengan bahagia dan sejahtera merupakan dambaan semua orang. Keadaan ini hanya dapat dicapai bila merasa sehat secara fisik, mental (jiwa) dan sosial. Berkaitan dengan kesehatan jiwa ini salah satunya adalah penyakit dcpresi. Depresi mcrupakan pcnyakit gangguanjiwa dengan prevalensi terbesar pada usia lanjut dan dan diperkirakan sampai 40% tidak terdiagnosa padahal dengan diagnosa awal dan terapi segera dapat menaikkan kualilas hidup, status fungsional dan mencegah kematian dini pada usia lanjut. Untuk mengctahui apa pcnycbabnya maka dilakukan penelitian ini yang bertujuan untuk mcngctahui faktor-faktor risiko yang bcrhubungan dcngan dcprcsi pada usia lanjut di wilayah Jabodetabek (Jakarta, Bogor, Depok, Tangerang dan Bekasi). Metodologi pada penelitian ini merupakan disain kasus kontrol dengan menggunakan data sekunder melalui penelusuran rekam medik pasien gcriatri di poli geriatri rumah sakil Cipro Mangunkusumo pada tahun 2006 - tahun 2008. Populasi penelilian adalah seluruh pasien usia lanjut di poli geriatri rumah Sakit Cipto Mangunkusumo. Sampel adalah pasien usia Ianjur di poli geriatri RSUPN-CM yang menderila diagnosa depresinya dan telah ditegakkan diagnosanya oleh departemen psikiatri RSUPN-CM scbagai kasus dan kontrol adalah pasien usia Ianjut di poli geriatri RSUPN-CM yang tidak depresi. Jumlah sampel dalam penelitian ini 105 kasus dan 2I0 kontrol. Entri data, pengolahan dan analisis data menggunakan SPSS Hasil penelitian mcnunjukkan bahwa variabel yang berhubungan dengan kejadian depresi pada usia lanjum adalah kcmandirian (OR = 2,008. 95% Cl I,239 - 3253) dan dukungan sosial (OR = l_724_ 95% C`| 1.065 - 2.79l). Variabel kemandirian merupakan variabel yang lebih kuat pengaruhnya terhadap kejadian depresi dibandingkan variabel dukungan sosial. Variabel yang tidak berhubungan dengan kqiadian depresi pada usia lanjut adalah usia, jcnis kclamin. status perkawinan, tingkat pendidikan, obat resep dokter yang diminum rutin, kegiatan keagamaan, keadaan ekonomi dan riwayar pekerjaan. Dari temuan pada penelitian ini disarankan untuk mcningkatkan pembinaan dan pcrhatian lerhadap kcbutuhan usia Ianjul agar usia Ianjut hidup mandiri, produktif dan tetap berperan aktif dalam kehidupan serta diperlukan penelitian kasus kontrol lanjutan dengan menggunakan sampel yang lebih besar.
With growing of a spark of life age in indonesia hence old age population even also progressively increase. Experiencing a period to old happyly and securc and prosperous is everybody hungering. This situations only can reach by if feeling lit by lisik. bouncing (social and mental). Relating to health of this head one of them is disease of depresi. Depresi is disease of head trouble with biggest prevalensi at old age and estimated until 40% do not diagnosa though with diagnosa early and therapy immediately can boost up the quality of lil' e, functional status and prevent death early at old age. To know what the cause of hence conducted by this research with aim to to know risk factors related to depresi at old age in region of Jabodetabek ( Jakarta, Bogor, Depok, Tangerang and ol' Bekasi). Methodologies this research is to bc designed by case control by using data of sekunder through of patient sis record of geriatri in hospital geriatri poli of Cipto Mangunkusumo in the year 2006 - year 2008. Research population is entire old age patient in hospital geriatri poli of`Cipto Mangunkusumo. Sampel is old age patient in RSUPN-CM geriatri poli which suffering the diagnosa of him and have been upheld the by him of by psychiatry department of RSUPN-CM as control and case is old age patient in RSUPN-CM geriatri poli which do not depresi. Amount oi" sampel in this researchs t05 ease and 2I0 control. Data Entri, data analysis and processing use SPSS version I3.0. Research result indicatc that variable rclatcd to occurcncc of depresi at old age is independence ( OR = $2,008. 95% CI l,239 - 3,253) and social support ( OR = l.724. 95% Cl l.065 - 2,79l). independence variable is stronger variable ofinfluence of to occurcncc ofdepresi compared to social support variable. Variable which do not relate to occurence of depresi at old age is age, gender, marriage status. education level. drinkcd by doctor recipe drug is routine, religious activity. situation ofwork history and economics. Of finding at this research is suggested to improve attcntion and construction to requirement of old agc so that self-supponing life old age. ad for and remain to share active in life is and also needed by research of case control continuation by using larger ones sampel.
Gagal jantung merupakan salah satu jenis penyakit jantung dengan insiden, prevalen serta mortalitas yang terus meningkat. Penelitian ini bertujuan untuk mengetahui pengaruh keteraturan berobat terhadap kesintasan lima tahun penderita gagal jantung kongestif (GJK). Desain penelitian adalah kohort retrospektif. Sampel sebanyak 402 orang penderita baru GJK yang didiagnosis antara tahun 2001 s.d. 2002 dan dirawat di Rumah Sakit Pusat Jantung dan Pembuluh Darah Harapan Kita. Ditemukan penderita GJK yang meninggal selama lima tahun follow up adalah 78 orang (19,4%). Probabilitas kesintasan penderita GJK adalah sebesar 88,65% (tahun pertama), 80,11%(tahun ke dua). 72.22% (tahun ke tiga), 63,75% (tahun ke empat) dan 54,41% (tahun ke lima). Penderita GJK yang tidak teratur berobat mempunyai risiko kematian lebih tinggi dari pada yang berobat teratur. Pada analisis Cox regression keteraturan berobat merupakan yariabel independen pada kesintasan penderita GJK (HR:1,95; 95% Cl: 1.23-3.11). Faktor-faktor Iain yang juga bermakna terhadap kesintasan penderita GJK adalah Ejection Fraction (HR:1,91; 95% Cl:1,18-3,08), Diabetes Melitus (HR:1,85; 95% Cl:1,08-3,18). Beberapa variabel pada penelitian ini hubungannya tidak bermakna terhadap kesintasan penderita GJK yaitu: umur, rokok,functional, riwayat PJK , hipertensi , kreatinin dan tindakan pengobatan. Keteraturan berobat terbukti mempengaruhi probabilitas kesintasan penderita GJK. Penderita GJK disarankan untuk senantiasa melakukan pemeriksaan dan pengobatan secara teratur.
Heart failure is one of cardiovascular disease which incidence, prevalence and mortality remain height and increased. The purpose of this study was to evaluate the effect of routine medical evaluation (compliance) on five year survival rate of patients hospitalized due to congestive heart failure. The Study design used in this study is retrospective cohort with 402 patients of newly diagnosis congestive heart failure (CHF) admitted in year 2000 to 2001 at National Cardiovascular Center - Harapan Kita, Jakarta. During 5 year follow-up, 78 patients died. Survival at 1 to 5 years was in order of 88,65%, 80,11%, 72,22%, 63,75%, and 54,41%, respectively. CHF patients who did not underwent routine medical evaluation had higher prognostic of death than CHF patients who had medical evaluation routinely. By Cox regression analyses, the independent predictors of mortality were routine evaluation (HR:1,95; 95% CI: 1.23-3.11). low ejection fraction (HR:1,91; 95% CI:1,18-3,08), and diabetes mellitus (HR:1,85; 95%CI:1,08-3,18). Other predictors were not statistically significant, i.e: age, gender, smoking, functional class, coronary heart disease, creatinine, and the medication. The status of compliance is an independent predictor of survival for patients with CHF, besides low ejection tiaction and diabetes mellitus. These evaluation, like the other research, suggested the importance of compliance in the treatment of CHF.
Heart failure is a clinical syndrome that occurs when the heart fails to meet the body’s demand for oxygen and nutrients. The prevalence and mortality rate of heart failure in Indonesia are relatively high compared to other Southeast Asian countries. The occurrence of heart failure in young adults increases the risk of premature death, recurrent rehospitalization, reduced quality of life, and a greater burden on the healthcare system. Several factors such as obesity, type 2 diabetes mellitus (T2DM), hypertension, smoking, dyslipidemia, family history of premature coronary artery disease (PCAD), and sex have been identified as being associated with heart failure. Developing a predictive model to identify the most influential risk factors for heart failure in young adults is crucial for preventive strategies and early interventions. This study employed a fixed retrospective cohort design involving patients aged 18–54 years who visited the cardiology outpatient clinic or were hospitalized at four tertiary hospitals in Indonesia (National Cardiovascular Center Harapan Kita, Jakarta; Hasan Sadikin Hospital, Bandung; Sebelas Maret University Hospital, Solo; and Adam Malik Hospital, Medan) in 2021. Patients without an initial diagnosis of heart failure were included, and their risk factors were recorded according to the study variables. The patients were followed monthly from 2021 until the end of observation in 2024 to determine whether they developed heart failure. Descriptive, bivariate, and multivariable analyses were conducted using the Poisson Generalized Linear Model (GLM) to estimate coefficients, incidence rate ratios (IRR) with 95% confidence intervals, and to construct the most accurate predictive model. Based on the model, a scoring system and probability value for the occurrence of heart failure were developed. A total of 321 participants met the inclusion and exclusion criteria, with a median age of 51 years (P25–P75: 46–52 years). After four years of observation, the cumulative probability of developing heart failure was 0.713 (95% CI: 0.661–0.760). The analysis identified three significant predictors for heart failure in young adults: obesity (IRR 1.87; 95% CI 1.31–2.68), dyslipidemia (IRR 2.58; 95% CI 1.87–3.56), and T2DM (IRR 2.79; 95% CI 2.01–3.87). The IDD Score (Body Mass Index–Dyslipidemia–Diabetes) was developed as a predictive scoring system for heart failure in young adults, with a total score of 13 corresponding to a 76.8% probability. Obesity, dyslipidemia, and T2DM were found to be significant risk factors for heart failure in young adults. The proposed IDD Score demonstrated good sensitivity and specificity in predicting the occurrence of heart failure within this population.
Kata Kunci: Kanker payudara, kesintasan hidup, stadium kanker, RSCM
Based on GLOBOCAN data of 2012, the highest incidence of cancer in Indonesia is breast cancer. Currently there are still many deaths caused by breast cancer. The survival of breast cancer survivors depends on several factors that are very important to know, including the stage of cancer. This study aims to determine the effect of stage of cancer, age, education, occupation, marriage, health insurance status, family history, type of therapy and distance of residence to survival of breast cancer survivors. The study design used a retrospective cohort method. Samples in this study were 135 breast cancer patients who were first diagnosed with breast cancer from January 2007 to June 2012 at RS Cipto Mangunkusumo. Data analysis using SPSS program and Kaplan Meier method and related factors were analyzed with Cox regression. The results of bivariable analysis showed that the stage of cancer had a significant relationship to survival of breast cancer (p value = 0,000; HR 19,227 (95% CI 1,395-265,101)). While in the analysis of mutivariabel the relationship of stage to life survival is not significant (p value = 0,102) after controlled by education variable, work, therapy type and interaction of cancer stage with education of patient. The survival of breast cancer survivors in early stage of breast cancer was higher (94.1%) than those in advanced stage (70.1%). Patients with advanced stage 11 times higher risk than the early stage (HR = 10,923; 95% CI 0.623-191,417). So needed awareness and efforts to early detection of breast cancer to further improve survival of breast cancer patients.
Keywords: Breast cancer, life survival, cancer stage, RSCM
