Penelitian ini membahas tentang kesehatan kerja yang bertujuan untuk melakukan manajemen risiko, dimulai dengan identifikasi bahaya, analisis dan evaluasi risiko dan mengetahui besaran risiko bahaya yang terdapat pada kegiatan kerja di Instalasi Ptologi RSUP Fatmawati. Disain penelitian deskriptif kualitatif dengan pendekatan semikuantitatif untuk analisis risiko. Teridentifikasi bahaya risiko tinggi yaitu terpajan spesimen dan terpajan bahan infeksius pada penggunaan pipet. Risiko substansial yaitu pada bahaya kebakaran dan ledakan. Risiko sedang yaitu bahaya terkerna pecahan tabung, petridis, dan object glass yang mengandung bahan infeksius, tertusuk jarum suntik, bahaya zat kimia, terkena sengatan listrik, terkena siraman air panas dan mata lelah. Telah dilakukan pengendalian bahaya di laboratorium ini yaitu engineering control, standard operating procedures dan APD, namun masih terdapat risiko residu pada bahaya tersebut dan telah direkomendasi pengelolaan dan pengendalian risikonya. Kata Kunci: Laboratorium mikrobiologi klinik, manajemen risiko, penilaian risiko

 This study discusses about the occupational health which aims to conduct risk management, it begins from hazards identification, risk analysis and risk evaluate, and find out the magnitude of risk hazards which found in work activities of Pathology Installation in RSUP Fatmawati. This research is qualitative descriptive interpretive with a semiquantitative approach to risk analysis. Identified of high risk hazards are specimen exposure and exposed to infectious material on the use of  pipette. Substantial risk are fire and explosion hazards. Moderate risk are the fractional hazard of tube, petridisc, and objects glass that contain infectious material, needle stick, chemical hazards, electrical shock, exposure to hot water and eyes fatigue. Hazard control has been performed in this laboratory, that is engineering controls, standard operating procedures (SOP) and PPE, but there are still residual risks and hazards risk management and risk control has recomended. Key Word: Clinical microbiology laboratory, risk management, risk assessment