Asam urat merupakan produk akhir dari metabolisme purin. Nilai normal asam urat serum pada wanita adalah 4,0 ± 1,0 mg/dl dan pada laki - laki 5,1 ± 1,0 mg / dl. Kadar asam urat dapat disebabkan oleh beberapa faktor diantaranya adalah karakteristik responden (usia, jenis kelamin, tingkat pendidikan, pengetahuan), asupan zat gizi (purin, protein, vitamin C, lemak, serat, asam folat),gaya hidup (kopi, soft drinks, olah raga, merokok) dan IMT. Tujuan dari penelitian ini adalah untuk mengetahui faktor determinan terhadap kadar asam urat pada kelompok orang dewasa di Desa Pabuaran Gunung Sindur Bogor.

Disain penelitian yang digunakan adalah cross-sectional dengan sampel sebanyak 66 responden. Penelitian dilakukan pada bulan Mei-Juni 2012. Analisis statistik deskriptif pada data numerik disajikan dalam bentuk rata-rata ± SD, sedangkan data nominal dan ordinal dalam bentuk proporsi.

Analisis statistik inferensial menggunakan uji t independen, ANOVA, korelasi pearson product moment dan regresi linear ganda dilakukan untuk mengetahui faktor dominan. Rata-rata kadar asam urat responden 4,64 ± 1,19 mg/dl dengan rata-rata kadar asam urat pria yaitu 5,88 ± 1,30 dan wanita yaitu 4,31 ± 0,92. Terdapat hubungan yang signifikan antara jenis kelamin dan merokok dengan kadar asam urat. IMT merupakan faktor dominan terhadap kadar asam urat setelah dikontrol usia, jenis kelamin, tingkat pendidikan, asupan purin rendah, dan asupan vitamin C.

Uric acid is the end product of purine metabolism. Normal level of serum uric acid for women is 4,0 ± 1,0 mg/dl and for men is 5,1 ± 1,0 mg / dl. An elevated uric acid level can be caused by several factors of which is respondents characteristics (age, gender, level of education, knowledge), nutrient intake (purine, protein, vitamin C, fat, dietary fiber, folic acid), life style (coffee, soft drinks, sport, smoking) and BMI. This research was aim to know determinant factor of uric acid level at group of adult in Pabuaran Countryside, Gunung Sindur Subdistrict, Bogor Regency.

Research design used by cross sectional study with 66 sample. This research was performed on May-June 2012. Descriptive statistic analysis on numeric data were presented as mean ± SD, while nominal and ordinal data in proportion.

Inferential statistic analysis with t test independen, ANOVA test, pearson product moment corellation was performed and multiple linear regression was used to know the dominant factor. Mean uric acid level was 4,64 ± 1,19 mg/dl with Mean uric acid consentration for men was 5,88 ± 1,30 dan for women was 4,31 ± 0,92. gender and smoking was significantly associated with uric acid level. BMI was dominance factor to uric acid level after controlled by age, sex, level of education, low purine intake and vitamin C intake.