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ABSTRAK Nama : Ikke Yuniherlina NPM : 1506704434 Program Studi : Epidemiologi Komunitas Judul : Faktor-faktor yang berhubungan dengan keparahan DBD pada pasien studi demam akut di delapan rumah sakit di Indonesia Manifestasi klinis demam berdarah dengue (DBD) masih menjadi permasalahan dalam kesehatan masyarakat di Indonesia. Berdasarkan derajat keparahan DBD menurut kritera WHO 2011 terbagi atas DBD derajat I, DBD derajat II, DBD derajat III, dan DBD derajat IV. Di Indonesia insiden DBD meningkat walaupun angka kematiannya menurun, untuk itu penelitian ini bertujuan meneliti faktor-faktor yang berhubungan dengan keparahan DBD, dimana DBD derajat II, III, dan IV dikategorikan sebagai DBD parah. Penelitian cross-sectional yang menggunakan data sekunder dari studi etiologi demam akut dari delapan rumah sakit di Indonesia, didapatkan proporsi keparahan DBD sebesar 43,3%. Faktor-faktor yang berhubungan dengan keparahan DBD didapatkan faktor jenis serotipe virus DENV-2 (OR = 3,06 95%CI 1,43 – 6,55), DENV-3 (OR = 2,62 95% CI 1,33 – 5,15), faktor lama demam (OR = 1,91 95%CI 1,09 – 3,35), dan faktor jumlah leukosit (OR = 1,79 95%CI 1,02 – 3,16). Skoring didapatkan sebesar 67% kemampuan untuk memprediksi keparahan. Kata kunci: keparahan, demam berdarah dengue, faktor-faktor
ABSTRACT Name : Ikke Yuniherlina NPM : 1506704434 Study Program : Epidemiology Title : Prognostic factors associated with dengue hemorrhagic fever severity of the acute fibril illness study patients in eight hospitals in Indonesia Dengue hemorrhagic fever (DHF) as a clinical manifestasion of dengue infection remains a public health problem in Indonesia. According to WHO, DHF severity grade was divided into DHF I, DHF II, DHF III and DHF IV. In Indonesia, the incidence of DHF increased eventhough the mortality rate decreased. Therefore, the study aims to examine prognostic factors related to the severity of DHF, with the category of severe DHF is including DHF II, DHF III and DHF IV. This cross-sectional study using secondary data from the Acute Febrile Illness Etiology Study of eight Hospitals in Indonesia. The result as follow, the proportion of severe DHF category is 43.3%, the prognostic factors associated with DHF severity are DENV serotype (DENV-2, OR = 3.06 95% CI 1.43 - 6.55; DENV-3, OR = 2.62 95% CI 1.33 - 5.15), day of illness (OR = 1.91 95% CI 1.09 - 3.35), and leucocyte count (OR = 1.79 95% CI 1.02 - 3.16). The scoring with contributing of DENV serotype, day of illness, and leucocyte count as prognostic factors, has only 67% ability to predict DHF severity. Keywords: severity, dengue hemorrhagic fever, prognostic factors
The succesful of TB patient treatment most depends on patient compliance in
treatment process in term of medication regurally, cure, and repeated
laboratorium confirmation test. Failer in treatment could lead into multi drug
resistant. Hence, monitoring patient contracting the disease in early stages can
help to predict that dotb motivator roles very important. The focus of this study
is to understanding the influence of Muhammadiayh Aisyiyah TB motivator
activities in the patient compliance in treatment process at early stages. This
study takes place at koja and cilincing sub district, North Jakarta starts from
januari 2009 to mei 2010. The research method is using restrosfective cohort.
The subject of study group divides into two groups. One group accompanied
with TB motivators and another without TB motivators. The subject comes from
the same register. . Sample selected by total sampling with a total of 110 patiens.
Data analysis was descriptive, bi-variate, stratification and causal model by
multivariate. Exellent TB motivators in TB treatment process have a bigger
proportion (77,9%) than fair TB motivator (57,14%). Each motivator has a
relationship with compliance for example promoting, counseling, PMO, and
motivator assistance. Multivariate analysis result gives an information the
relationship between motivator role and high compliance treatment after
controlling confounding variables such as age and knowledge. An excellent
motivator has 2,11 times to increase compliance compare with fair motivator
(95% CI 0,87 – 5.11)
Keywords: Motivator, TB, Compliance,
Dengue Hemorrhagic Fever is an endemic disease in most parts of Indonesia, including in other tropical regions. Nutritional status is closely related to a person's immunological status related to immunopathogenesis of DHF. The purpose of this study was to determine the relationship of stunting with the incidence of DHF in toddlers in Sumbawa Regency. The study design that will be used in this study is an analytic study with a case control design. Case samples will be taken from all cases, and for control samples will be taken by using a random sample technique (Simple Random Sampling). So it can be concluded the number of cases 97 (total cases) of families who have toddlers with DHF diagnoses from 2018 to March 2020 (from 5 working areas of puskesmas with the highest number of DHFs in toddlers) while control of 194 families who have toddlers who are neighboring cases. From the bivariate results it can be concluded that there is a significant relationship between nutritional status and the incidence of DHF in children under five in Sumbawa Regency (p value = 0.0001) with OR = 3,269 (95% CI: 1,757-6,083). In multivariate analysis showed the same thing (p value = 0.0001) with OR = 3.22 (95% CI: 1,679-6,174). This shows that toddlers with short and very short nutritional status increase the risk of 3.22 times getting DHF.