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The aim of the study was to determine the factors influencing job satisfaction among medical doctors working at the framework of Basic Package of Health Services in Afghanistan. This study utilized data derived from National Health Services Performance Assessment was conducted on 2008 in Afghanistan. Health workers interview instrument was used to know the perspective of health workers from health services. This study sample size was 548 participants. The results revealed almost 54% of participants were not satisfied with their job. Variables such as low salary/lack of salary, lack of equipment, lack of supplies and drugs, lack of motivation and security of health facility area were found to be significantly associated with medical doctors? satisfaction of job.