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Kriteria utama obesitas menurut WHO adalah IMT namun obesitas sentral lebih berhubungan dengan risiko kesehatan dibanding obesitas umum Tujuan penelitian untuk mendapatkan cut off point dari ketiga indikator dalam mendeteksi terjadinya DMT2. Juga untuk mengetahui hubungan obesitas dengan indikator IMT, LP dan rasio LP-TB dengan terjadinya DMT2 dan menentukan indikator mana yang lebih baik dari ketiganya. Desain Cross Sectional. menggunakan data sekunder. Analisis menggunakan regresi logistic dan metode ROC.
Hasil : prevalensi DMT2 9,1% dan prevalensi obesitas berkisar 38,37 % - 41,98 % Nilai cut off obesitas umum IMT ≥ 25,72 kg/m2, LP laki-laki ≥ 80,65 cm perempuan ≥ 80,85 cm dan LP-TB laki-laki ≥ 0,51 perempuan ≥ 0,55.
Kesimpulan : orang dengan obesitas meningkatkan risiko terjadinya DMT2 setelah dikontrol faktor umur. Karena hasil ketiga indikator tidak jauh berbeda, maka penggunaanya tergantung keputusan praktisi kesehatan itu sendiri.
The WHO's major obesity criteria is BMI but central obesity is more associated to health risks than general obesity. The objective of the research is to define the cut off points of the three measurements in detecting the occurrence of T2DM. It is also aimed to examine the relationship of obesity indicators (BMI, WC, and WHtR) with T2DM and determine the best indicator of them. Design of Cross Sectional employs secondary data. Analysis apply logistic model and ROC method.
The result: prevalence of type 2 DM is about 9.1%, and obesity prevalence is about 38.37 % to 41.98 %. The cut off values of BMI general obesity, male WC, female WC, male WHtR, and female WHtR are ≥ 25.72 kg/m2, ≥ 80.65 cm, ≥ 80.85 cm, ≥ 0.5, and ≥ 0,55 respectively.
Conclusion: adjusted by age, obesity increases the risk of type 2 DM occurrence. Since there is no significantly different result, the use of obesity indicators depends on the health practitioner decisions.
ABSTRAK
Penyakit jantung koroner merupakan pembubuh utama di negara maju maupunnegara berkembang. Salah satu faktor risiko utama penyebab arterosclerosis adalahhiperkolesterolemia yang ditunjukkan dengan peningkatan kadar kolesterol LDL.Perubahan pola hidup yang ditandai dengan kurangnya mengkonsumsi buah dansayuran serta banyak mengkonsumsi makanan yang tinggi lemak, merupakan salahsatu risiko terjadinya peningkatan kadar kolesterol LDL. Penelitian ini bertujuanuntuk mengetahui hubungan asupan serat dengan kadar kolesterol LDL pendudukusia 25-65 tahun di Kelurahan Kebon Kalapa Bogor tahun 2013. Penelitian dilakukandengan desain cross sectional menggunakan data baseline Studi Kohor Faktor RisikoPenyakit Tidak Menular Badan Litbangkes tahun 2011. Analisis multivariatemenggunakan regresi logistik. Hasil analisis data diperoleh proporsi kolesterol LDLtinggi sebesar 78.3% dengan rata-rata kadar kolesterol 120 mg/dl. Rata-rata asupanserat sebesar 7 gram/hari dengan proporsi asupan serat <6.6 gram/hari sebesar 50.5%.Hasil multivariate menunjukkan asupan serat rendah merupakan faktor protektif (OR= 0.182) terhadap kadar kolesterol LDL tinggi setelah dikontrol oleh variabel umur,asupan lemak dan asupan protein nabati. Faktor determinan dalam model ini terhadapkadar kolesterol LDL adalah asupan protein nabati (OR = 13.356). Model ini mampumemprediksi kejadian kadar kolesterol LDL sebesar 79.4% dan sisanya dipengaruhioleh variabel lain yang tidak tercantun didalam model. Dengan melakukanpenyuluhan akan pentingnya mengkonsumsi makanan yang banyak mengandungserat merupakan salah satu upaya pencegahan terjadinya penyakit yang berhubungandengan arterocslerosis. Merubah pola makan dengan memperbanyak konsumsi buahakan mengurangi kadar kolesterol LDL dalam darah.
ABSTRACT
Coronary heart disease considers as one of the major killers both in developedand developing countries. One of the main risk factors that caused artherosclerosis ishypercholesterolemia which indicates by elevated LDL cholesterol level. Life stylechanging by lack of consuming fruits and vegetables while excess in consuming foodhigh in fat content considered one of risk to have elevated cholesterol level. The aimof this research is to identify the relationship between fiber consumption and thecontent of LDL cholesterol for the people of 25-65 years of age at Kebon KelapaVillage in Bogor on the Year of 2013. The research is conducted by Cross Sectional.The analytic design utilizes the baseline data from Cohort Study of ContagiousDisease Risk Factors of the Research and Development of Health Agency of theRepublic of Indonesia in the year of 2011. Stratification is used in analyzing data andcog regression is utilized in multivariate analysis. The analysis of the result obtainedthat the prevalence of LDL cholesterol is 78.3% with the average of cholesterolcontent 120 mg/dl. The average of daily fiber consumption is 7 gram/day with theproportion of fiber consumption <6.6 gram/day is 50.5%. The result of multivariateanalysis indicates that low fiber consumption considers as a protective factor(OR=0.182) toward high level of LDL cholesterol level after having controlled bysuch variables as age, consumptions of fat and vegetable protein. Determinant factorin this model toward LDL cholesterol content is the consumption of vegetable protein(OR=13.356). This model has the ability to predict in experiencing LDL cholesterollevel 79.4% and the remaining would be influenced by other factors that have notwritten down in the model. By educating the community about the important ofconsuming high fiber foods consider as one of the effort to prevent the occurrence ofdiseases relate with artherosclerosis. Changing the eating pattern by consuming morefiber will decrease the content of cholesterol level in the blood
ABSTRAK Nama : Purwo Setiyo Nugroho Program Studi : Magister Epidemiologi Judul : Hubungan Diabetes Melitus Dengan Penyakit Jantung Koroner (Analisis Data Baseline Kohor PTM Tahun 2011). Diabetes mellitus merupakan salah satu penyakit yang dapat menimbulkan komplikasi yang berakibat munculnya penyakit lainnya. Penyakit kardiovaskuler merupakan penyakit terbesar pada penderita diabetes mellitus. Penyakit jantung koroner merupakan penyakit kardiovaskuler terbanyak dibandingkan penyakit kardiovaskuler lainnya. Penelitian ini bertujuan untuk mengetahui hubungan diabetes mellitus dengan penyakit jantung koroner pada studi data Baseline Kohor PTM Kementrian Kesehatan. Analisis yang digunakan adalah Cox Regression yang mengestimasi nilai Prevalens Ratio. Hasil analisis multivariat dengan menggunakan analisis cox regression mengungkapkan bahwa orang yang menderita diabetes melitus memiliki prevalens rasio sebesar 1,094 kali (p value 0,929 CI 95 % 0,149 – 8,026) dibanding responden yang tidak menderita diabetes melitus. Namun, hasil analisis ini menunjukkan bahwa hubungan diabetes melitus terhadap penyakit jantung koroner tidak signifikan dengan mempertimbangkan nilai p value > 0,05 dan 95 % Confidence Interval yang rentangnya melewati angka 1. Dalam peneltian ini minim terjadinya bias seleksi karena tidak missing data pada sampel eligible sebanyak 1937 responden. Begitu pula minim terjadinya bias informasi karena pengukuran variabel penelitian menggunakan alat ukur yang baku. Namun penelitian ini memiliki kelemahan dalam temporality sehingga hasil penelitian tidak dapat di justifikasi bahwa diabetes mellitus merupakan penyebab penyakit jantung koroner. Serta nilai asosiasi prevalence ratio bukan merupakan nilai risiko yang sebenarnya. Kata Kunci : Diabetes Melitus, Penyakit Jantung Koroner, Baseline Kohor, Penyakit Tidak Menular
ABSTRACT Name : Purwo Setiyo Nugroho Program : Master of Epidemiology Title : Association of Diabetes Mellitus With Coronary Heart Disease (Baseline Data Analysis of Non-Communicable Disease, 2011). Diabetes mellitus is a disease that can cause complications that lead to the emergence of other diseases. Cardiovascular disease is the biggest disease in patients with diabetes mellitus. This study aims to determine the relationship of diabetes mellitus and coronary heart disease in the Baseline Data Non-Communicable Disease Cohort Study. The analysis is the Cox Regression estimate the Prevalence Ratio. Multivariate analysis using Cox regression analysis revealed that people suffering from diabetes mellitus have a prevalence ratio of 1.094 times (p value = 0.929 95% CI 0.149 to 8.026) than respondents who do not have diabetes mellitus. However, the results of this analysis showed that the association of diabetes mellitus against coronary heart disease is not significant considering p value <0.05 and 95% Confidence Intervals range is exceeded 1. This study the minimal selection bias because there is missing data on a sample of eligible total 1937 respondents. Similarly, the minimal bias variable measurement information for research using standard measurement tools. However, this study has weaknesses in temporality so that research results can not be justified that diabetes mellitus is a cause of coronary heart disease. Tthe value of association prevalence ratio is not the value of the actual risk. Keywords: Diabetes Mellitus, Coronary Heart Disease, Baseline Cohort, Non Communicable Disease
Prediabetes is a global public health issue. Prevalence of prediabetes isincreasing worldwide. Generally, it is high among adults and as a high risk statefor DM. Obesity has essential role in pathophysiology of prediabetes. This studyaimed to explore whether both of general obesity and abdominal obesity related toprediabetes on age group 20-65 years in Bogor tengah sub-district by familyhistory of DM, sex, age, smoking, hypertension, physical activity and stress. Thisstudy used the cross sectional design study with Cox Regression to multivariableanalysis. Data for this analysis were collected during the baseline stage of cohortstudy of risk factors of non-communicable disease in 2011-2012. There were3244 respondents from Bogor tengah were taken by random sample technique..The result indicated that obesity to prediabetes adjusted by age; general obesityalone PR 1,58 (95% CI: 1,17-2,15), abdominal obesity alone PR 1,45 (95% CI;1,19-1,87), general obesity and abdominal obesity jointly PR 1,92 (95% CI;1,62-2,28). Therefore, general obesity and abdominal obesity jointly contributedmost to the increase prevalence of prediabetes. Awareness raising and screeningof prediabetes of those at high risk group by assessing obesity by BMI and waistcircumference joinlty are essential to be considered as part of efforts for haltingthe epidemic of prediabetes in community.Keyword : general obesity, abdominal obesity, prediabetes.
Cardiomegaly (enlarged heart/cardiac enlargement) is not a disease but a sign andsymptom of other medical conditions. It can be dilatation, hypertrophy, orventricular dilatation. It is more often pathological. It does not give rise tocomplaints, in early stage. The complaints will be felt when it has entered theadvance stage and ended in heart failure. Cardiomegaly established byexamination of chest x-rays, which is expressed by CTR ≥ 50%. The purpose ofthe study determine the relationship of obesity on the incidence of cardiomegaly.Using secondary data and cross-sectional design.The results is presence of therelationship of obesity on the incidence of cardiomegaly. Multivariate Coxregression analysis showed PR 3.5 (95% CI: 1.46 to 8.37) after adjusted for age,gender, history of hypertension and history of CHD. There is interaction ofobesity with age in this study are outlined in the discussion. Conclusions obesityis not sole cause in this study, but the presence of cardiomegaly may aggravate therisk of heart failure and alert to risk of mortality.Keywords : cardiomegaly, cardiac enlargement/enlarged heart, obesity
