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The existence of landfill can be a source of manganese (Mn) pollutants in the environment. Mn can cause toxic for kidney if excessive intake. The purpose of this study was to determine the relationship between Mn concentrations in ground water with kidney function disorders in the people living around the Cipayung Landfill. The research was a cross sectional study with 104 respondents which included Cipayung and Pasir Putih village. Kidney function disorders was determined by the level of proteinuria or hematuria determined by the semi-quantitative dipstick method. While the Mn measurements used SNI 6989.5: 2009. The results showed that Mn levels of ground water at 9 (13,6%) sampling points exceeded drinking water quality standards and 17 people (16.3%) showed changes in kidney function. Mn concentration were between 0.06 mg / L-0.84 mg /L. There was no relationship between Mn concentration in ground water with kidney function disorders. While risk factors for hypertension and obesity had a significant relationship with kidney function disorders (OR 4.20; 95%; CI: 1.27-13.84;
OR 3.64; 95%; CI: 1.10-12.07). The conclusions of this study is risk factors for hypertension and obesity have a significant relationship with kidney function disorders.
ABSTRAK Nama : Lisa Felina Program Studi : Epidemiologi Judul : Hubungan obesitas sentral dengan gangguan fungsi ginjal pada jemaah Haji penderita diabetes melitus tipe 2 (Analisis data sekunder Siskohatkes Shar’i tahun 1438 H / 2017 M) Latar belakang: Gangguan fungsi ginjal pada tahap awal sangat jarang diketahui karena belum memunculkan tanda dan gejala. Saat gangguan fungsi ginjal berkembang progresif dan muncul penyakit ginjal terminal hingga hemodialisis akan menyebabkan status kesehatan jemaah haji menjadi risiko tinggi dan dapat menjadi tidak memenuhi syarat istithaah. Perlu dilakukan evaluasi lebih awal dengan mengetahui faktor risiko yang berhubungan dengan gangguan fungsi ginjal seperti obesitas sentral untuk mendapatkan upaya pencegahan dan intervensi yang lebih menguntungkan. Tujuan: Mengetahui prevalensi gangguan fungsi ginjal dan hubungan obesitas sentral dengan gangguan gangguan fungsi ginjal pada jemaah haji penderita DM tipe 2. Metode: Penelitian ini menggunakan desain cross sectional terhadap 2.106 jemaah haji yang menderita DM tipe 2. Subyek diperoleh dari data sekunder Siskohatkes Shar’i Puskeshaji Kemenkes RI tahun 1438 H / 2017 M. Semua subyek dilakukan pemeriksaan kesehatan di puskesmas atau rumah sakit rujukan. Estimasi nilai LFG menggunakan persamaan CKD EPI untuk menentukan fungsi ginjal. Obesitas sentral ditentukan menggunakan indeks lemak visceral. Analisis menggunakan regresi logistik multivariat. Hasil: Nilai rata-rata estimasi LFG 78,63 ml/menit/1,72 m 2 . Prevalensi gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2 sebesar 39,55%. Prevalensi gangguan fungsi ginjal pada Jemaah haji penderita DM tipe 2 dengan obesitas sentral adalah 29,17%. Obesitas sentral berhubungan signifikan secara statistik dengan gangguan fungsi ginjal pada jemaah haji penderita DM tipe 2. Nilai adjusted OR sebesar 1,45 (95% CI 1,19 – 1,77). Kesimpulan: Prevalensi gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2 sebesar 39,55%. Obesitas sentral berhubungan secara signifikan dengan gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2. Kata kunci: gangguan fungsi ginjal, obesitas sentral, indeks lemak visceral, jemaah haji
ABSTRACT Nama : Lisa Felina Program Studi : Epidemiologi Judul : Association of central obesity with renal function impairment among Indonesian pilgrim with type 2 diabetes mellitus (Siskohatkes Shar’i secondary data analysis year 1438 H / 2017 M) Background: Impaired renal function in the early stages often not raised signs and symptoms. End-stage renal disease with hemodialysis will cause Indonesian pilgrims in high risk health status and does not meet istithaah requirements. Early detection of risk factors such as central obesity might be directed to benefit prevention dan intervention. Objective: to estimate the prevalence of renal function impairment in type 2 DM and the association of central obesity with renal function impairment among Indonesian pilgrim with type 2 DM based on Siskohatkes shar’i 1438 H / 2017 M. Methods: This cross sectional studi consisted of 2.106 Indonesian pilgrims with type 2 DM. The data was obtained from Siskohatkes 2017 of Pilgrimage Health Center, Ministry of Health. The variable data analyzed were creatinin serum, anthropometric, age, gender, smoking, family history of end-stage renal disease, blood pressure, HDL, LDL, trigliserida and uric acid. Renal function impairment was defined according to Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation to estimate Glomerulus Filtration Rate (eGFR). Central obesity was determined using visceral adiposity index (VAI). Multivariable logistic regression was used to analyze the association of central obesity and renal function impairment. Result: The prevalence of renal function impairment in Indonesia pilgrim with type 2 DM was 39,55%. The mean of eGFR was 78,63 ml/min/1,72 m 2 . Central obesity was associated with renal function impairment (adjusted OR = 1,45; 95% CI 1,19–1,77). Conclusion: The prevalence of renal function impairment in Indonesia pilgrim with type 2 DM was 39,55%. Central obesity was associated with renal function impairment. Kata kunci: renal function impairment, central obesity, visceral adiposity index, pilgrim
