Ditemukan 2 dokumen yang sesuai dengan query :: Simpan CSV
Eva Yulianti; Pembimbing: Nurhayati Adnan; Penguji: Helda, Dina Garniasih, Fajar Subroto
Abstrak:
Leukemia limfoblastik akut (LLA) adalah jenis kanker yang disebabkan oleh akumulasi limfoblas di sumsum tulang yang mempengaruhi banyak anak. Keberhasilan pengobatan pada pasien leukemia dapat dinilai berdasarkan tingkat kelangsungan hidup pasien LLA. Tujuan dari penelitian ini adalah untuk mengidentifikasi kelangsungan hidup 5 tahun, faktor-faktor yang mempengaruhinya, dan nilai skor prediktor kelangsungan hidup pada anak usia 1-18 tahun yang didiagnosis dengan leukemia limfoblastik akut (LLA) di RSAB Harapan Kita. Penelitian ini adalah penelitian observasional analitik yang menggunakan desain penelitian kohort retrospektif. Sampel adalah 130 pasien LLA yang didiagnosis pada tahun 2013-2014 yang diperoleh dari teknik pengambilan sampel non-probabilitas jenis consecutive sampling. Data dikumpulkan dengan melacak rekam medis pasien. Data dianalisis menggunakan analisis Kaplan-Meier dan Regresi Cox. Hasil penelitian menunjukkan bahwa probabilitas tingkat kelangsungan hidup pasien LLA tahun 2013-2014 adalah 92,25% dengan tingkat kelangsungan hidup rata-rata 60 bulan. Berdasarkan analisis multivariat menggunakan model interaksi regresi Cox, faktor yang paling berpengaruh pada tingkat kelangsungan hidup pasien LLA adalah komorbiditas (p = 0,002; HR = 10,76 CI; 2,38-48,55), remisi (p = 0,001; HR = 13,28 CI2,98- 59,73) dan kambuh (p = 0,014; HR = 7,92 CI; 1,53-41,12).
Acute lymphoblastic leukemia (LLA) is a type of cancer caused by the accumulation of lymphoblasts in the bone marrow that affects many children. The success of treatment in leukemia patients can be assessed based on the survival rate of LLA patients. The aims of this study were to identify 5-year survival, the factors that influence it, and the scoring value of predictors of survival in children aged 1-18 years diagnosed with acute lymphoblastic leukemia (LLA) in RSAB Harapan Kita. This study is an analytic observational study that used retrospective cohort study design. The sample was 130 LLA patients diagnosed in 2013-2014 who were obtained from a non-probability sampling technique consecutive sampling. Data were collected by tracking the patient's medical records. Data were analyzed using KaplanMeier analysis and Cox Regression. The results show that the LLA patient's survival rate probability from 2013-2014 was 92.25% with a median survival rate of 60 months. Based on multivariate analysis using Cox regression interaction models, the most influential factors on survival rate of LLA patients were comorbidity (p = 0.002; HR = 10.76 CI; 2.38-48.55), remission (p = 0.001; HR = 13.28 CI2.98-59.73) and relapse (p = 0.014; HR = 7.92 CI; 1.5341.12)
Read More
Acute lymphoblastic leukemia (LLA) is a type of cancer caused by the accumulation of lymphoblasts in the bone marrow that affects many children. The success of treatment in leukemia patients can be assessed based on the survival rate of LLA patients. The aims of this study were to identify 5-year survival, the factors that influence it, and the scoring value of predictors of survival in children aged 1-18 years diagnosed with acute lymphoblastic leukemia (LLA) in RSAB Harapan Kita. This study is an analytic observational study that used retrospective cohort study design. The sample was 130 LLA patients diagnosed in 2013-2014 who were obtained from a non-probability sampling technique consecutive sampling. Data were collected by tracking the patient's medical records. Data were analyzed using KaplanMeier analysis and Cox Regression. The results show that the LLA patient's survival rate probability from 2013-2014 was 92.25% with a median survival rate of 60 months. Based on multivariate analysis using Cox regression interaction models, the most influential factors on survival rate of LLA patients were comorbidity (p = 0.002; HR = 10.76 CI; 2.38-48.55), remission (p = 0.001; HR = 13.28 CI2.98-59.73) and relapse (p = 0.014; HR = 7.92 CI; 1.5341.12)
T-6014
Depok : FKM-UI, 2020
S2 - Tesis Pusat Informasi Kesehatan Masyarakat
☉
Hartini; Pembimbing: Tri Krianto; Penguji: Rita Damayanti, Dian Ayubi, Nana Mulyana, Muh. Danial Umar
Abstrak:
Kekambuhan skizofrenia merupakan masalah yang terjadi di Rumah Sakit JiwaProvinsi Kalimantan Barat di Kota Singkawang. Jumlah penderita skizofrenia yangkambuh terjadi peningkatan disetiap bulannya. Berdasarkan data dari Rumah Sakit Jiwa Provinsi Kalimantan Barat tahun 2014 dari bulan Januari 48, Februari 55, Maret 60.Penelitian ini bertujuan untuk mengetahui informasi mengenai gambaran kekambuhan pada penderita skizofrenia di Kota Singkawang Provinsi Kalimantan Barat tahun 2014.Desain penelitian yang dipakai yaitu metode kualitatif, penelitian ini dilakukan padabulan Mei-Juni 2014 teknik pengumpulan data menggunakan wawancara mendalam.Hasil penelitian, penderita kambuh dan tidak kambuh terlihat bahwa pada keluargapenderita skizofrenia yang kambuh dukungan keluarga (pengetahuan, sikap, budaya,stigma) dan kepatuhan minum obat. Variabel tersebut yang mempengaruhi terjadinya kekambuhan terlihat bahwa masih ada keluarga yang memperlakukan penderitadengan kasar dan hanya memperhatikan minum obatnya saja namun kenyataannyamasih ada penderita yang tidak teratur minum obat. Sedangkan pada kasuspembanding yaitu pada keluarga penderita yang kambuh justru sebaliknya. Sedangkan pada kedua kelompok ini budaya disetiap suku terlihat penanganan yang berbeda-beda.Di butuhkan program terapi keluarga pada Rumah Sakit Jiwa Provinsi Kalimantan Barat di Kota Singkawang Kata Kunci : Kekambuhan skizofrenia, dukungan keluarga, keluarga penderita kambuh dan tidak kambuh
Schizophrenia relapses is a problem that occurs in SingkawangMental Hospital, WestKalimantan Province. The number of patients with schizophrenia who relapseincreased every month. Based on the data, there was an increase of cases fromJanuary (48 cases), February (55 cases), and March (60 cases).The aims of this study isto find out information about the relapse overview inschizophrenia patients at Singkawang West Kalimantan Province in the year of2014.The study design used is a qualitative method. The study was conducted inMay-June 2014.In-depth interviewstechniques was used for data collection.The results showed there are five variables that influence the occurrence of relapse,ie family support (knowledge, attitudes,culture, stigma)and drug compliance. Thereare families still treat the patients with rude and only pay attention to take hismedication alone but in fact there are still people who do not regularly takemedication. While in the case of the comparison which is to the patient's family, justthe opposite is happening. While in the both groups, the handling look the difrent inevery cultures.Family therapy program is needed at the SingkawangMental Hospital, WestKalimantan Province.Keywords :schizophrenia relapses, family support, families of relapse and not-relapse patients
Read More
Schizophrenia relapses is a problem that occurs in SingkawangMental Hospital, WestKalimantan Province. The number of patients with schizophrenia who relapseincreased every month. Based on the data, there was an increase of cases fromJanuary (48 cases), February (55 cases), and March (60 cases).The aims of this study isto find out information about the relapse overview inschizophrenia patients at Singkawang West Kalimantan Province in the year of2014.The study design used is a qualitative method. The study was conducted inMay-June 2014.In-depth interviewstechniques was used for data collection.The results showed there are five variables that influence the occurrence of relapse,ie family support (knowledge, attitudes,culture, stigma)and drug compliance. Thereare families still treat the patients with rude and only pay attention to take hismedication alone but in fact there are still people who do not regularly takemedication. While in the case of the comparison which is to the patient's family, justthe opposite is happening. While in the both groups, the handling look the difrent inevery cultures.Family therapy program is needed at the SingkawangMental Hospital, WestKalimantan Province.Keywords :schizophrenia relapses, family support, families of relapse and not-relapse patients
T-4144
Depok : FKM-UI, 2014
S2 - Tesis Pusat Informasi Kesehatan Masyarakat
☉
