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Kematian akibat kanker di dunia semakin meningkat baik di negara maju maupun berkembang. Di Indonesia, data menunjukkan hal yang serupa. Badan Litbangkes melaporkan bahwa berdasarkan hasil laporan laboratorium Patologi Anatomi tahun 1990, kanker serviks menempati urutan pertama dari 3 kanker yang tersering dijumpai. Registrasi kanker di Indonesia yang berdasarkan kependudukan belum ada Berita penelitian yang berkaitan dengan ketahanan hidup kanker serviks sangat kurang. Tujuan penelitian adalah untuk mengetahui hubungan stadium klinik dengan ketahanan hidup 5 tahun pada pasien kanker serviks setelah dikontrol oleh variabel konfounding. Desain penelitian ini adalah kohort retrospektif pada 451 subyek penelitian dengan mengunakan data rekam medis pada diagnosis tahun 1993-1996 yang diikuti selama 5 tahun. Hasil penelitian ini menyimpulkan bahwa probabilitas ketahanan hidup 5 tahun pasien kanker serviks dengan stadium I sekitar 70%, stadium II sekitar 37,4%, stadium III sekitar 12,4%, dan stadium IV pada tahun kedua sudah menjadi 0%. Pada kadar Hb 10 gr/dl dan dikontrol oleh besar tumor dan jenis histologik maka peluang untuk meninggal pada stadium II sebesar 2,7 kali, Pada stadium III sebesar 19,2 kali. sedangkan stadium IV sebesar 6,6 kali dibandingkan dengan stadium I. Pada kadar Hb 10 gr/dl dan dikontrol oleh besar tumor dan jenis histologik maka peluang untuk meninggal pada stadium II sebesar 0,6 kali. pada stadium III sebesar 3.08 kali, sedangkan stadium IV sebesar 6,6 kali dibandingkan dengan stadium I, Berdasarkan hasil penelitian ini kepada masyarakat, disarankan untuk melakukan pemeriksaan dini. Kepada petugas rumah sakit dan pembuat kebijakan untuk melakukan promosi yang berkelanjutan tentang pentingnya pemeriksaan dini kanker serviks. Secara umum, juga disarankan agar dimulai registrasi kanker berdasarkan kependudukan untuk mempermudah penelitian yang berkaitan kanker terutama kanker serviks.
Cancer deaths in the world are increasing in both developed and developing countries. In Indonesia, data shows something similar. The Health Research and Development Agency reported that based on the results of the 1990 Anatomical Pathology laboratory report, cervical cancer ranks first out of 3 most common cancers. Cancer registration in Indonesia based on population does not yet exist. Research news related to cervical cancer survival is very lacking. The purpose of this study was to determine the relationship between clinical stage and 5-year survival in cervical cancer patients after being controlled by confounding variables. The design of this study was a retrospective cohort of 451 research subjects using medical record data at diagnosis in 1993-1996 which was followed for 5 years. The results of this study concluded that the probability of 5-year survival of cervical cancer patients with stage I is around 70%, stage II around 37.4%, stage III around 12.4%, and stage IV in the second year has become 0%. At Hb levels of 10 gr/dl and controlled by tumor size and histological type, the chance of dying in stage II is 2.7 times, in stage III it is 19.2 times. while stage IV is 6.6 times compared to stage I. At Hb levels of 10 gr/dl and controlled by tumor size and histological type, the chance of dying in stage II is 0.6 times. in stage III it is 3.08 times, while stage IV is 6.6 times compared to stage I. Based on the results of this study, it is recommended to the public to conduct early examinations. To hospital staff and policy makers to carry out ongoing promotion of the importance of early cervical cancer examinations. In general, it is also recommended to start cancer registration based on population to facilitate research related to cancer, especially cervical cancer.
Malignant pleural effusion (MPE) often appears in patients with lung cancer anddeteroriates prognosis of patients with mean survival rate of 6 months. This studyaims to look at the characteristics and survival of lung cancer patients with MPE(stage IIIB or IV) at Dharmais Cancer Hospital Jakarta in 2009-2013. Studydesign was longitudinal cohort with univariate and survival analysis. Sample waslung cancer patients with metastatic MPE based on cytology test or biopsy withcomplete medical record. Results showed average age of patients was 58.73; mostwere male, nonsmoker, and pensioner. Majority of patients had respiratorydisorder, adenocarcinoma cancer type, reached stage IV, and effusion in the rightlung. Approximately 68.5% of patients surviving 6 months after diagnosis andmedian survival were 12.5 months. IEC is needed for community; especiallypopulation with lung cancer risk, to help reducing number of new patients seekingtreatment after cancer reaches advanced stage.Keyword: malignant pleural effusion,characteristics, survival.
