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Kata kunci: Diabetes mellitus (DM), Mild Cognitive Impairment (MCI), Lansia
Diabetes mellitus is a risk factors of Mild Cognitive Impairment (MCI). MCI is a transition phase between healthy cognitive aging and dementia. The purpose of this study is to determaine the association between diabetes mellitus in elderly with the incidence of MCI in Cipayung Health Center, Depok city. Study design was cross sectional using primary data with validated Montreal cognitive test for Indonesia (MoCa-Ina). Total sample of 272 elderly people age more than 60 years-old. cox regression analysis were applied in the research. The result of study showed the prevalence of MCI is 47,1% and elderly with DM is 17,3%. The result of multivariate analysis showed the elderly people with diabetes mellitus probably had 2,4 risk to get MCI (PR = 2,436 95% CI: 1,191-4,983) than elderly with no diabetes after adjusted with hypertention and interaction diabetes with hypertention variable. Screaning early detection of MCI in elderly with diabetes mellitus is early intervention to prevent to dementia.
Key words: Diabetes mellitus (DM), Mild Cognitive Impairment (MCI), Elderly
Obesity is a process of abnormal or excessive fat accumulation that can harm a person's health. Obesity can be determined by measuring the body mass index (BMI), which is a person's body weight (in kilograms) divided by the square of their height (in meters). A person with a BMI of 25 or more is categorized as obese according of Asia Pacific obesity classification. Objective of this study was to determine the relationship of obesity to get incidence of disability in the elderly who has diabetes mellitus in Indonesia in 2018. Variables in this study were obesity, disability, age, sex, physical activity, stress, asthma, hypertension and heart disease. This study using secondary data from Basic Health Research (Riskesdas) 2018 with cross sectional design. The population of this study was the elderly who has diabetes mellitus (ever diagnosed by a doctor and or currently taking DM drugs). The minimum number of samples in this study was 1233 elderly respondents who has diabetes mellitus. This study was analyzed till the multivariate stage used of Logistic Regression. The results of this study found was a significant relationship between obesity to get incidence of disability in elderly who has diabetes mellitus in Indonesia in 2018 with a POR value of 2.509 (95% CI; 1.136 - 5,539). The meaning is, obese for elderly with an age range of 75-90 years have a 2,509 times chance compared to the non-obese elderly with an age range of 60-74 years. Increasing the achievement of program posbindu PTM, so that as early to find risk factors obesity to be prevented immediately.
ABSTRAK Nama : Lisa Felina Program Studi : Epidemiologi Judul : Hubungan obesitas sentral dengan gangguan fungsi ginjal pada jemaah Haji penderita diabetes melitus tipe 2 (Analisis data sekunder Siskohatkes Shar’i tahun 1438 H / 2017 M) Latar belakang: Gangguan fungsi ginjal pada tahap awal sangat jarang diketahui karena belum memunculkan tanda dan gejala. Saat gangguan fungsi ginjal berkembang progresif dan muncul penyakit ginjal terminal hingga hemodialisis akan menyebabkan status kesehatan jemaah haji menjadi risiko tinggi dan dapat menjadi tidak memenuhi syarat istithaah. Perlu dilakukan evaluasi lebih awal dengan mengetahui faktor risiko yang berhubungan dengan gangguan fungsi ginjal seperti obesitas sentral untuk mendapatkan upaya pencegahan dan intervensi yang lebih menguntungkan. Tujuan: Mengetahui prevalensi gangguan fungsi ginjal dan hubungan obesitas sentral dengan gangguan gangguan fungsi ginjal pada jemaah haji penderita DM tipe 2. Metode: Penelitian ini menggunakan desain cross sectional terhadap 2.106 jemaah haji yang menderita DM tipe 2. Subyek diperoleh dari data sekunder Siskohatkes Shar’i Puskeshaji Kemenkes RI tahun 1438 H / 2017 M. Semua subyek dilakukan pemeriksaan kesehatan di puskesmas atau rumah sakit rujukan. Estimasi nilai LFG menggunakan persamaan CKD EPI untuk menentukan fungsi ginjal. Obesitas sentral ditentukan menggunakan indeks lemak visceral. Analisis menggunakan regresi logistik multivariat. Hasil: Nilai rata-rata estimasi LFG 78,63 ml/menit/1,72 m 2 . Prevalensi gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2 sebesar 39,55%. Prevalensi gangguan fungsi ginjal pada Jemaah haji penderita DM tipe 2 dengan obesitas sentral adalah 29,17%. Obesitas sentral berhubungan signifikan secara statistik dengan gangguan fungsi ginjal pada jemaah haji penderita DM tipe 2. Nilai adjusted OR sebesar 1,45 (95% CI 1,19 – 1,77). Kesimpulan: Prevalensi gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2 sebesar 39,55%. Obesitas sentral berhubungan secara signifikan dengan gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2. Kata kunci: gangguan fungsi ginjal, obesitas sentral, indeks lemak visceral, jemaah haji
ABSTRACT Nama : Lisa Felina Program Studi : Epidemiologi Judul : Association of central obesity with renal function impairment among Indonesian pilgrim with type 2 diabetes mellitus (Siskohatkes Shar’i secondary data analysis year 1438 H / 2017 M) Background: Impaired renal function in the early stages often not raised signs and symptoms. End-stage renal disease with hemodialysis will cause Indonesian pilgrims in high risk health status and does not meet istithaah requirements. Early detection of risk factors such as central obesity might be directed to benefit prevention dan intervention. Objective: to estimate the prevalence of renal function impairment in type 2 DM and the association of central obesity with renal function impairment among Indonesian pilgrim with type 2 DM based on Siskohatkes shar’i 1438 H / 2017 M. Methods: This cross sectional studi consisted of 2.106 Indonesian pilgrims with type 2 DM. The data was obtained from Siskohatkes 2017 of Pilgrimage Health Center, Ministry of Health. The variable data analyzed were creatinin serum, anthropometric, age, gender, smoking, family history of end-stage renal disease, blood pressure, HDL, LDL, trigliserida and uric acid. Renal function impairment was defined according to Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation to estimate Glomerulus Filtration Rate (eGFR). Central obesity was determined using visceral adiposity index (VAI). Multivariable logistic regression was used to analyze the association of central obesity and renal function impairment. Result: The prevalence of renal function impairment in Indonesia pilgrim with type 2 DM was 39,55%. The mean of eGFR was 78,63 ml/min/1,72 m 2 . Central obesity was associated with renal function impairment (adjusted OR = 1,45; 95% CI 1,19–1,77). Conclusion: The prevalence of renal function impairment in Indonesia pilgrim with type 2 DM was 39,55%. Central obesity was associated with renal function impairment. Kata kunci: renal function impairment, central obesity, visceral adiposity index, pilgrim
