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Abstrak: Vaksinasi tetanus toksoid merupakan intervensi pencegahan tetanus yang terbukti efektif secara klinis. Program vaksinasi tetanus toksoid di negara berkembang sering kali terhambat karena keterbatasan budget yang dialokasikan untuk program vaksinasi, berkompetisi dengan intervensi kesehatan lainnya pada kondisi belanja kesehatan semakin meningkat. Efektivitas klinis perlu bersinergi dengan efektivitas biaya agar dapat mencapai keberhasilan program. Efektivitas biaya program dapat dinilai dengan evaluasi ekonomi. Penelitian ini bertujuan untuk mengidentifikasi teknik evaluasi ekonomi pada vaksinasi tetanus toksoid pada ibu hamil. Kajian literatur dilakukan pada Mei 2020 sampai Juli 2020 dengan pencarian pada database CINAHL, Cochrane Library, dan PubMed. Kajian literatur mengikuti panduan Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for Scoping Review. Diperoleh 4 studi yang memenuhi kriteria. Diidentifikasi 3 studi menggunakan teknik CUA, 2 studi menggunakan teknik CEA (dengan 1 studi menggunakan kedua teknik) dengan membandingkan intervensi vaksinasi TT dengan do nothing/ current practice. Luaran akhir keempat studi berupa incremental cost-effectiveness ratio (ICER). ICER pada 3 studi menghasilkan kesimpulan bahwa intervensi vaksinasi TT pada ibu hamil memiliki value for money. Diperoleh suatu bukti bahwa vaksinasi dengan tetanus toksoid efektif secara biaya bahkan pada negara-negara yang belum berhasil mengeliminasi tetanus neonatal atau baru mengeliminasi tetanus neonatal secara parsial. Dari berbagai kemungkinan, vaksinasi tetanus toksoid pada ibu hamil selalu dominan dibanding komparator, berlaku pada one way sensitivity analysis dan analisis sensitivitas probabilistik simulasi Monte Carlo. Kata kunci: Tetanus toksoid, vaksinasi TT, vaksinasi maternal, evaluasi ekonomi, analisis efektivitas biaya, analisis utilitas biaya Tetanus toxoid vaccination is an intervention aiming preventing tetanus which clinically proven to be effective. Tetanus vaccination program in developing countries is frequently hampered due to limited budget allocated for vaccination program, competing with other health interventions as health expenditure increases. Clinical effectiveness should be synergized with cost-effectiveness in order to achieve program success. Economic evaluation is an approach to assess cost effectiveness. This study aims to identify economic evaluation techniques of tetanus toxoid vaccination for pregnant women. Literature review was conducted from May 2020 to July 2020 by performing literature search in databases of CINAHL, Cochrane Library, and PubMed. This literature review conformed to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines for Scoping Review. Obtained 4 studies fulfilled the criteria. Identified 3 studies used CUA, 2 studies used CEA (with 1 study used both techniques) comparing TT vaccination intervention with the absence of program scenario (do nothing) or current practice. Outcomes of 4 studies are incremental cost-effectiveness ratio (ICER). ICERs obtained from 3 studies present the evidence that TT vaccination intervention for pregnant women has value for money. This study obtained an evidence that tetanus toxoid vaccination is cost-effective even among countries which have yet to eliminate or have partially eliminated neonatal tetanus. Across various probabilities, tetanus toxoid vaccination in pregnant women remains dominant compared to the comparator, holds in one way sensitivity analysis and probabilistic sensitivity analysis via Monte Carlo simulation. Keywords: Tetanus-toxoid, TT vaccination, maternal vaccination, economic evaluation, cost effectiveness analysis, cost utility analysis