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Ischemic heart disease is one of causes of mortality on Indonesia pilgrims. Based on the results of surveillance done by the central government pilgrim health 2015 M, a death resulting from ischemic heart disease as many as 20,76% of the total death from cardiovascular diseases. Research objectives to assess factors that deals with death from ischemic heart disease on Indonesia pilgrims of 2015 M / 1436 H, covering factors age, sex, the acts of hypertension, the acts of dislipidemia and the acts of diabetes mellitus. The research was done at the center for health hajj in April - June 2016.
ABSTRAK Nama : Lisa Felina Program Studi : Epidemiologi Judul : Hubungan obesitas sentral dengan gangguan fungsi ginjal pada jemaah Haji penderita diabetes melitus tipe 2 (Analisis data sekunder Siskohatkes Shar’i tahun 1438 H / 2017 M) Latar belakang: Gangguan fungsi ginjal pada tahap awal sangat jarang diketahui karena belum memunculkan tanda dan gejala. Saat gangguan fungsi ginjal berkembang progresif dan muncul penyakit ginjal terminal hingga hemodialisis akan menyebabkan status kesehatan jemaah haji menjadi risiko tinggi dan dapat menjadi tidak memenuhi syarat istithaah. Perlu dilakukan evaluasi lebih awal dengan mengetahui faktor risiko yang berhubungan dengan gangguan fungsi ginjal seperti obesitas sentral untuk mendapatkan upaya pencegahan dan intervensi yang lebih menguntungkan. Tujuan: Mengetahui prevalensi gangguan fungsi ginjal dan hubungan obesitas sentral dengan gangguan gangguan fungsi ginjal pada jemaah haji penderita DM tipe 2. Metode: Penelitian ini menggunakan desain cross sectional terhadap 2.106 jemaah haji yang menderita DM tipe 2. Subyek diperoleh dari data sekunder Siskohatkes Shar’i Puskeshaji Kemenkes RI tahun 1438 H / 2017 M. Semua subyek dilakukan pemeriksaan kesehatan di puskesmas atau rumah sakit rujukan. Estimasi nilai LFG menggunakan persamaan CKD EPI untuk menentukan fungsi ginjal. Obesitas sentral ditentukan menggunakan indeks lemak visceral. Analisis menggunakan regresi logistik multivariat. Hasil: Nilai rata-rata estimasi LFG 78,63 ml/menit/1,72 m 2 . Prevalensi gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2 sebesar 39,55%. Prevalensi gangguan fungsi ginjal pada Jemaah haji penderita DM tipe 2 dengan obesitas sentral adalah 29,17%. Obesitas sentral berhubungan signifikan secara statistik dengan gangguan fungsi ginjal pada jemaah haji penderita DM tipe 2. Nilai adjusted OR sebesar 1,45 (95% CI 1,19 – 1,77). Kesimpulan: Prevalensi gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2 sebesar 39,55%. Obesitas sentral berhubungan secara signifikan dengan gangguan fungsi ginjal pada jemaah haji yang menderita DM tipe 2. Kata kunci: gangguan fungsi ginjal, obesitas sentral, indeks lemak visceral, jemaah haji
ABSTRACT Nama : Lisa Felina Program Studi : Epidemiologi Judul : Association of central obesity with renal function impairment among Indonesian pilgrim with type 2 diabetes mellitus (Siskohatkes Shar’i secondary data analysis year 1438 H / 2017 M) Background: Impaired renal function in the early stages often not raised signs and symptoms. End-stage renal disease with hemodialysis will cause Indonesian pilgrims in high risk health status and does not meet istithaah requirements. Early detection of risk factors such as central obesity might be directed to benefit prevention dan intervention. Objective: to estimate the prevalence of renal function impairment in type 2 DM and the association of central obesity with renal function impairment among Indonesian pilgrim with type 2 DM based on Siskohatkes shar’i 1438 H / 2017 M. Methods: This cross sectional studi consisted of 2.106 Indonesian pilgrims with type 2 DM. The data was obtained from Siskohatkes 2017 of Pilgrimage Health Center, Ministry of Health. The variable data analyzed were creatinin serum, anthropometric, age, gender, smoking, family history of end-stage renal disease, blood pressure, HDL, LDL, trigliserida and uric acid. Renal function impairment was defined according to Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation to estimate Glomerulus Filtration Rate (eGFR). Central obesity was determined using visceral adiposity index (VAI). Multivariable logistic regression was used to analyze the association of central obesity and renal function impairment. Result: The prevalence of renal function impairment in Indonesia pilgrim with type 2 DM was 39,55%. The mean of eGFR was 78,63 ml/min/1,72 m 2 . Central obesity was associated with renal function impairment (adjusted OR = 1,45; 95% CI 1,19–1,77). Conclusion: The prevalence of renal function impairment in Indonesia pilgrim with type 2 DM was 39,55%. Central obesity was associated with renal function impairment. Kata kunci: renal function impairment, central obesity, visceral adiposity index, pilgrim
Angka prevalensi diabetes melitus dari tahun ke tahun cendenmg meningkat. Data Departemen Kesehatan menyebutkan jumlah pasien dan kematian diabetes melitus rawat inap maupun rawat jalan di rumah sakit menempati urutan pertama dad selumh penyakit endokrin. Tahun 2004 pasien rawat inap diabetes melitus 42.000 kasus CFR 7,9%; dan tahun 2006 meningkat menjadi 49.364 kasms CFR 8,42%. Dari 4 (cmpat) tipc diabetes melitus, maka diabetes melitus tipe 2 yang paling banyak. Prevalensi diabetes melitus tipc 2, tahun 1992 sebesar 5,69%, tahun 1993 meningkat menjadi 5,'7% dan tahun 2005 mcnjadi l4,7%. Penyakit tersebut merupakan masalah kesehatan yang sangat serius, dimana komplikasinya menimbulkan angka kematian yang cukup tinggi, dan beban biaya kesehatan yang cukup mahal. Untuk itu diperlukan usaha untuk mencegahnya. Tujuan penelitian ini untuk mengetahui hubungan antara obesitas sentral dengan kejadian diabetes melitus tipe 2 setelah dikontrol variabel kovariat. Beberapa faktor kovariat yang diduga meningkatkan jumlah penderita diabetes melitus tipe 2 antara Iain umur, jenis kelamin, pekerjaan, riwayat menderita DM, aktivitas fisik, konsumsi serat, konsumsi lemak, pola makan, konsumsi alkohol, dan merokok. Desain penelitian ini menggunakan rancangan kasus kontrol dengan jumlah responden 300 orang dimana masing-masing kasus dan kontrol sebanyak 150 responden. Analisis dilakukan secara bertahap mulai dan analisis univariat, bivariat, dan multivariat. Analisis multivariat menggunakan analisis regresi Iogistik ganda. Hasil pcnclitian menunjukkan hubungan yang signiiikan antara obesitas sentral dengan kejadian diabetes melitus tipe 2 dimana obesitas sentral memiliki resiko untuk tcrkcna diabetes melitus tipe 2 sebesar 3,16 kali dibanding tanpa obesitas sentral, setelah dikcndalikan faktor riwayat DM dalam keluarga, aktiiitas fisik, dan kcbiasaan mcrokok. Disarankan perlunya informasi mengenai faktor resiko diabetes melitus tipc 2 secara luas kepada masyarakat. Jika risiko DM dapat diketahui sedini mungkin, maka upaya pencegahan akan segera dapat dilakukan schingga prevalcnsi DM dapat ditekan.
Diabetes mellitus prevalence number of year goes to tend to increase. Health Depanmen data describes that the total of patient and diabetes melitus death, inpatient care and also outpatient care at hospital stays in the first range of all endocrine’s disease. On 2004 the diabetes melitus patient of inpatient care are 42,000 cases with CFR 7.9% and on 2006 become increase to 49,364 cases with CFR 8.42%. From 4 (four) diabetes melitus type, therefore diabetes melitus type 2 becomes most transmitted on patients. Diabetes melitus type 2 prevalence on 1992 as 5.69%, on 1993 increase becomes 5.7% and on 2005 becomes l4.7%. That disease was really serious health problem, where its complication caused high mortality and health charge which adequately expensive. For those reason required all effort to prevent it. The purposed of this research to describes relationship among central obesity with diabetes melitus type 2 after controlled by covariate variable. Several preconceived covariate factor increases diabetes melitus type 2 patient for example age, gender, occupation, diabetes mellitus history, physical activity, Ebcr consumption, fat consumption, food habit, alcohol and smoking. This observational design utilize case control design with 300 person respondent where every cases and controls as 150 respondents. Analysis is performing in several phased from univariate analysis, bivariate, and multivariate analysis. Multivariate analysis using a multiple logistics regression. The observational result indicated the significant relationship among central obesity and occurrence of diabetes melitus type 2 where central obesity has a risk and tend to strikes by diabetes mellitus type 2 as 3.16 times compared without central obesity, after controlled by diabetes mellitus history in family, physical activity and Smoking habitual. Sugggested to publicized the sufficient and properly infomation conceming diabetes melitus type 2 to community. If diabetes melitus type 2 risk can be detected and known early, therefore prevention effort will be performed so diabetes melitus type 2 prevalence can be controlled.
Metode : Penelitian ini menggunakan disain cross-sectional. Sebanyak 26.301 Penduduk 40-65 tahun menjadi sampel pada penelitian ini. Data diperoleh dari Mandat Litbangkes RI dan dianalisis menggunakan uji Regresi Logistik.
Hasil : Risiko TB Paru 4,8 kali lebih besar pada penduduk 40-65 tahun yang memiliki riwayat diabetes mellitus dibandingkan dengan tidak memiliki riwyat diabetes mellitus (POR=4,8 : 95% CI 2,2-10,6).
Kesimpulan : Kolaborasi antar layanan termasuk didalamnya skrining (Diabetes Mellitus dan TB Paru) diperlukan untuk mengurangi prevalensi dari kedua penyakit dengan didukung penyusunan peraturan/pedoman standard antar layanan di FKTP serta pertimbangan pemberian profilaksis PP INH pada penderita diabetes mellitus perlu dipertimbangkan
Introduction : Indonesia is the third rank of the highest number cases of tuberculosis. On average 90% of those infected with M and only 10% develop active tuberculosis after infection (WHO, 2018). Diabetes attacked 382 million in 2013 and will be predicted increase to 592 million by 2035. When diabetes spreads, it will cause more people infected tuberculosis (Lönnroth, 2014). The prevalence of diabetes mellitus increases with age, especially in populations over 40 years due to the development of glucose intolerance. Therefore, it is necessary to do research to determine the risk of diabetes mellitus against pulmonary tuberculosis in the population of 40-65 years by considering the contributory factors (potential confounder) which are also related to the prevalence of tuberculosis and diabetes mellitus.
Method: This study used cross-sectional design. Sample were 26,301 respondents of 40- 65 years. Data was obtained from the Indonesian Litbangkes and analyzed using the Logistic Regression.
Result : The risk of pulmonary TB was 4,8 times greater in the population of 40-65 years who had a history of diabetes mellitus compared to not having a diabetes mellitus (POR = 4,8 : 95% CI 2,2-10,6).
Conclusion : Collaboration both health services including screening (Diabetes Mellitus and Pulmonary TB) is needed to reduce the prevalence of both diseases and profilaxis program of PP INH need to be considered
