Ditemukan 30655 dokumen yang sesuai dengan query :: Simpan CSV
500 mg with Vitamin E 200 mg to Decrease Oxidative Stress and Increase Antioxidant on Technician Crew Military Aircraft. Oxidative stress is pathological condition body that is caused by imbalance between oxidants with antioxidants body, which produces free radicals that can lead cell damage early. Free radical will bind building blocks cell covering of fat, protein and DNA will result damage cell, so cell can not regenerate that affect onset of degenerative diseases. Technicians crew military aircraft as specialized personnel with activity job direct contact with material oxidant, thus high risk of oxidative stress. Vitamin C and vitamin E are antioxidant enzyme exogen outside body which has role inhibiting oxidative stress, so oxidative stress does not occur. The design study experimental studies with intervention randomized double blind controled trial. Sample size 206 people divided into two groups are intervention group with sample size 103 people are given supplements combination vitamin C 500 mg with vitamin E 200 mg and control group with sample size 103 people are given placebo for 40 days without break. Data collected include are characteristics of respondent, pattern and amount of consumption of vitamin C, vitamin E and nutrient food, derived from food frequecy questionnaire (FFQ) and 24-hour recall, examination of oxidative stress by checking levels malondialdehyde (MDA) and examination of antioxidant by checking levels glutathione (GSH) in blood serum in pre and post intervention. The results showed decrease oxidative stress in group intervention who are received suplement combination vitamin C 500 mg with vitamin E 200 mg compared with control group who are received placebo, are significant with p value 0.04 with effects size -0.089 nmol/mL, confidence interval 95 % (-0.17875 - 0.00095). No increase antioxidants in group intervention who are received supplement combination vitamin C 500 mg with vitamin E 200 mg compared with control group who are received placebo, are not significant with p value 0.81 with effects size -0.019 ug/mL, 95% confidence interval ( -0.140 - 0.180).
ABSTRAK Penelitian berdesain kohort retrospektif yang bertujuan untuk mengetahui pengaruh KIH terhadap perilaku dalam perawatan Bayi Baru Lahir yang meliputi pelaksanaan IMD, pemberian ASI saja, pencegahan hipotermi dan perawatan tali pusat dilakukan di 9 Kelurahan di Kota Metro. Jumlah sampel 86 responden ibu yang memiliki bayi umur < 1 bulan terdiri dari 2 kelompok, yaitu terpapar KIH dan tidak terpapar KIH masing-masing 43 responden. Data yang terkumpul dianalisis secara univariat, bivariat dan multivariat dengan regresi logistik ganda model prediksi. Hasil penelitian menunjukkan bahwa faktor yang paling dominan berpengaruh pada perawatan bayi baru lahir yaitu; KIH pada perilaku IMD dan pemberian ASI saja, pengetahuan pada perilaku pencegahan hipotermi dan dukungan nakes pada perawatan tali pusat. Disarankan bagi penentu kebijakan untuk memasarkan program KIH sesuai dengan segmentasi pasar, meningkatkan kualitas penyampaian materi pencegahan hipotermi dan perawatan tali pusat. Kata Kunci : Kelas Ibu hamil, perawatan bayi baru lahir
ABSTRACT This retrospective cohort study aims to determine the effect of pregnancy class on behaviour in newborn care, including implementation of the immediate breast feeding, breastfeeding only, hypothermia prevention and the umbilical cord care. This study use to 86 respondent from mother which have newborn as a sample, consisting of exposed by pregnancy class and unexposed groups respectively 43 respondents. The Collected data were analyzed by univariat analysis, bivariate analysis and multivariate analysis by logistic regression using the prediction model. The result of study showed that the most dominant factors that are influential are; pregnancy class on immediate breastfeeding behaviour and breastfeeding only, the knowledge on the behaviour of hypothermia prevention and health workers support in umbilical cord care. Recommended for policy makers to make the role of pregnant mothers in the Pregnancy class activities becomes better, as the pregnancy class affect the behaviour of the well newborn care. Key Words : The Pregnancy Class, Newborn care
Penelitian ini dilakukan untuk mengetahui peran penggunaan obat antihiperlipidemia terhadap penurunan kadar kolesterol total.Penelitian analitik dengan rancangan Nested Case Control ini memanfaatkan data sekunder dari studi prospektif CARES (Cardiovascular Risk Estimation and Screening) tahun 2000 pada kelompok Crystal Club dan data primer untuk melengkapi kekurangan pada data. Dengan menggunakan total error laboratorium Prodia sebesar 10% maka kasus adalah mereka yang mengalami penurunan kadar kolesterol total 10% atau lebih selama kurang lebih satu bulan sedangkan kontrol adalah yang mengalami penurunan kadar kolesterol total kurang dari 10% atau mengalami peningkatan selama kurang lebih satu bulan juga.Dari 227 responden pada awal pemeriksaan terdapat 83,7% yang memiliki kadar kolesterol total > 200 mg/dl. Pada pemeriksaan yang kedua jumlah responden berkurang menjadi 191 responden. Untuk mengetahui peran penggunaan obat antihiperlipidemia dilakukan wawancara kembali. Dari 82 responden berhasil diwawancarai. Dari 82 responden 44 responden tidak menggunakan obat dan 38 responden menggunakan obat anttbiperlipidemia. Rata-rata penurunan terbesar diperoleh pada mereka yang menggunakan obat jenis atorvastatin yaitu sebesar 23,19%.Hasil penelitian menunjukkan bahwa penurunan kadar kolesterol total > 10% berhubungan dengan menggunakan obat antihiperlipidemia (OR = 5,91, 95% Cl 2,07 ; 16,88) dan pendidikan tinggi (OR = 5,28, 95% CI 1,59 ; 17,54) . Probabilitas penurunan kadar kolesterol total tertinggi pada mereka yang menggunakan obat antihiperlipidemia dan berpendidikan tinggi (75%). Bila dilihat dari jenis obat yang dikonsumsi maka penurunan kadar kolesterol total > 10% berhubungan dengan penggunaan obat jenis lain (OR = 1,35, 95% CI 0,28 ; 6,54), obat jenis statin lain (OR = 4,58, 95% CI 0,80 ; 26,04) dan obat jenis atorvastatin (OR = 19,93, 95% CI 4,21 ; 94,43) serta pendidikan tinggi (OR = 5,31, 95% Cl 1,40 ; 20,25). Probabilitas penurunan kadar kolesterol total tertinggi pada mereka yang menggunakan obat jenis atorvastatin dan berpendidikan tinggi (91%). Dan bila dilihat dari jumlah obat yang digunakan maka penurunan kadar kolesterol total berhubungan dengan penggunaan obat kurang dari 30 butir (OR = 3,36, 95% CI 0,75 ; 15,01) dan penggunaan obat sebanyak 30 butir selama satu bulan (OR = 7,47, 95% CI 2,33 ; 23,91) serta pendidikan tinggi (OR = 5,15, 95% CI 1,53 ; 17,30). Probabilitas penurunan kadar kolesterol total tertinggi pads mereka yang menggunakan obat antihiperlipidemia sebanyak 30 butir dan berpendidikan tinggi (80%).Berdasarkan hasil penelitian maka perlu dilakukan penelitian leblh lanjut untuk melihat efek dari penggunaan obat antihiperlipidemia terhadap penurunan risiko penyakit jantung koroner maupun risiko penyakit kardiovaskular lainnya.Daftar Pustaka : 64 (I982-2002)
The Role of Using Antihyperlipidernic on The Lowering of Total Cholesterol Level.The objective of this study is to examine the role of using antlhyperlipidemic on the lowering of total cholesterol level.This study is an analytical study with nested case control designed by using secondary data from prospective CARES (Cardiovascular Risk Estimation and Screening) study in 2000 and by using primary data to complete it. By using 10% total error from Prodia laboratory, the cases is people who get >10% decrease of total cholesterol level in one month, and control is people who get <10% decrease or increase of total cholesterol level as the same time.From 227 respondents in the early examination there are 83.7% who have X200 mg/dl total cholesterol level. In the second examination the number of respondents were decreased to 191 respondents. In order to examine the role of antihyperlipidemic, re-interview was conducted to 82 respondents. In which 38 respondents used the drugs whereas 44 didn't. Respondents who used atorvastatin had highest decrease of cholesterol level (23.19% on average).The result indicates that X10% decrease of total cholesterol level was related to the using of antihyperlipidemic (OR = 5.91, 95% CI 2.07 ; 16.88) and high educational level (OR - 5.28, 95% CI L59 ; 17.54). The highest probability of the decrease of total cholesterol level is people who take antihyperlipidemic and have high educational level (75%). According to the variety of drugs that being consumed, ?l0% decrease of total cholesterol level related to other drugs (OR = 1.35, 95% CI 0.28 ; 6.54), other statin drugs (OR = 4.58, 95% CI 0.80 ; 26.04), atorvastatin (OR = 19.93, 95% CI 4.21 ; 94.43), and people with high educational level (OR = 5.31, 95% CI 1.40 ; 20.25). The highest probability of decrease of total cholesterol level is people who take atorvastatin and high educational level (91%). According to the number of drug that being consumed, ?10% decrease of total cholesterol level was related to the use of < 30 pills antihyperlipidemic in one month (OR = 3.36, 95% CI 0.75 ; 15.01), the use of 30 pills in one month (OR = 7.47, 95% CI 2.33 ; 23.91), and who have high educational level (OR = 5,15, 95% CI 1,53 ; 17,30). The highest probability of the decrease of total cholesterol level is people who take 30 pills antihyperlipidemic in one month and high educational level (80%).Based on these results, it is very important to conduct several follow-up studies to confirm the effect of antihyperlipidemic on the decrease of coronary heart disease's risk or other cardiovascular diseases.References : 64 (1982-2002)
Acute Respiratory Infection (ARI) is one of cause of death in children indeveloping countries. Children have the highest risk in increased dose of PM10exposure. In last two years, ARI is one of the top ten diseases in Jatinegara. Thisstudy aimed to analyze the relationship of PM 10 in air in classroom with ARI inthe elementary school students in Jakarta. Study design was cross-sectional with353 students as sample, taken from 10 SDN in Jatinegara area. Variablesassociated with ARI in elementary school students are PM10 concentrations inclassrooms, ventilation in the kitchen, smoking behavior in house, uses ofmosquito repellent, and family members with ARI. Students with PM10concentrations in classrooms which not qualify the standards (> 70 ug / m3 ) hasthe risks 1,7 times in causing ARI after the controlled physical environmentalclass variables. Efforts should be made to prevent ARI include maintaining theclass cleanliness and regular maintenance, planting trees in school yard as air filter,clean and healthy life behavior, and make adequate ventilation for air circulationin rooms.Keywords: concentration of PM10 , ARI , Elementary School Students.