Abstrak:

---

---

Abstrak: WHO memperkirakan terdapat 8 juta penderita Down syndrome di dunia Penyebab yang spesifik belum diketahui, tapi kehamilan oleh ibu yang berusia diatas 35 tahun beresiko tinggi memiliki anak down syndrom. Pada ibu yang berusia lebih dari 35 tahun, insidensi meningkat sampai 1 dari 300 kelahiran. Sedangkan pada ibu usia di atas 40 tahun, insidensi meningkat secara drastis mencapai 1 dari 10 kelahiran

---

WHO estimates that there are 8 million people with Down syndrome in the world he specific cause is not yet known, but pregnancy by mothers over the age 35 years of high risk of having Down syndrome children. In mothers over 35 years of age, the incidence increases to 1 in 300 births. Meanwhile, for mothers over 40 years of age, the incidence increases drastically, reaching 1 in 10 births. This study aims to determine the relationship between maternal age at pregnancy and the incidence of Down syndrome in children aged 0-59 months in Indonesia based on 2018 Riskesdas data. t is necessary to educate productive women about the risks of pregnancy at old age

Abstrak: This study determines the prevalence of metabolic syndrome (MetS) according to the International Diabetes Federation (IDF) and National Cholesterol Education Program III (NCEP) criteria in Thai adults. Data from a national representative sample, InterASIA study, including a total of 5305 Thai adults 35 years and older were analyzed. Overall, the age-standardized prevalence of MetS by IDF and NCEP criteria were 24.0% (men 16.4%, women 31.6%) and 32.6% (men 28.7%, women 36.4%), respectively. The difference in prevalence of MetS between genders was much greater for the IDF compared with the NCEP definition. The age-standardized prevalence rates distributed by geographic region were relatively uniform with a lowest prevalence in the northeast. Among all possible sets of components for MetS, the most common combinations were a set of low high-density lipoprotein cholesterol, high triglyceride, and hyperglycemia in men (3.9%) and a set of abdominal obesity, low high-density lipoprotein cholesterol, and high triglycerides in women (6.7%). MetS is common in Thai adults and NCEP definition captures more cases of MetS compared with the IDF definition. Implementation of programs to prevent obesity and metabolic factors along with future periodic survey to monitor the problem is crucial.