Indonesia memiliki beban yang serius terhadap penyakit kardiovaskular, terutama PJK. Di Asia Tenggara, Indonesia memiliki angka kematian tertinggi akibat penyakit jantung. Prevalensi PJK berbasis diagnosis dokter tidak mengalami kenaikan, meski begitu, berdasarkan data Riskesdas 2013-2018, terjadi kenaikan terhadap prevalensi faktor risiko PJK. Beberapa faktor risiko PJK yang terjadi bersamaan menyebabkan sindrom metabolik, prevalensinya cukup tinggi di Indonesia dan meningkatkan risiko PJK. Tujuan penelitian ini adalah untuk mengetahui besar risiko sindrom metabolik terhadap terjadinya PJK di Indonesia. Penelitian ini menggunakan desain kohort retrospektif, dengan median masa pengamatan 6,8 tahun, data skunder IFLS4 tahun 2007 dan IFLS5 tahun 2014 pada 6.571 responden usia 40-69 tahun. Hasil penelitian mendapatkan prevalensi sindrom metabolik 20%, berdasarkan kriteria Joint Interim Statement. Kasus baru PJK 2,72%, dengan insiden rate 34 per 100.000 orang tahun. Analisis multivariat dengan uji cox regression mendapatkan HR 2,16 (95%CI 1,564-2,985), bahwa seseorang dengan sindrom metabolik memiliki risiko dua kali lebih tinggi untuk mengalami PJK dibanding tanpa sindrom metabolik setelah mengontrol variabel jenis kelamin, umur, status merokok, dan aktivitas fisik.

Respiration illness has some different symptoms basically is caused of irritation, failure of transparent muccociliari, more rekresi lender and respiration stricture. Children under tive years old at Primary Heath Care of Pangkalan Kerinci in Pelalawan District risk of respiration problem and based on result of annual report at Primary Health Care, respiration trouble illness is the tirst of ten illnesses at this area. lt is because of most public spend 90 % their time in room (house). Therefore research is pointed by the way of looking for relationship between PMN rate at house, house physical environment factor and children under tive years old characteristic which related to respiration problem occurrence becoming a reason. WHO estimated that there were 400-500 millions people who faced air pollution problem of variation room including headache, head cold, drought red lane, drought coughs, eye irritation, skin irritation, influenza, breathless and tuberculosis. This research purpose to know prevalence between respiration problem illness among children under tive years old, relationship of PMN rate at house, house physical environment factor (10 variables) and children under tive years old characteristic (5 variables) with respiration problem illness occurrence among children under tive years old, and looking for factor which is most dominance effect of respiration problem illness among children under tive years old at Primary Health Care of Pangkalan Kerinci, Pelalawan District in Riau Province, time period of Measurement appliance which is used to measure PM", rate at house consists of Haz Dust Sampler, EPAM S000 model, temperature by thennometer, dampness by hygrometer, illumination by luxmeter, and appliance which is used to get primary data of children under tive years old characteristic by questionnaire and checklist. 'l`his research used a cross sectional design which participating population of 615 Head of Family (KK) by sample number of 261 children under five years old, where data was collected at the same time of PMN, rate, house physic environment and children under five years old characteristic and there were not respiration problem illness occurrence among children under five years old. Based on research result which has been done it was indicated that: l). Prevalence of children under tive years old who faced of respiration problem illness was 78,2 % _ 2). Children under five years old house with PMN rate which did not fulfill requirement was 55,6 %, 3). There is no meaning ditference of PM", rate at house (p value = 0,393) with respiration problem among children under tive years old. 4). Habit of children under tive years old out of house has a meaning difference of respiration problem illness occurrence among children under tive years old by p- value = 0,007 and OR = 2,59 (95 % CI: 1,333-5,083). Children under ive years old who are out of house have risk of respiration problem illness 2,59 times compared with children under tive years old are out of house for long time. 5). Factor which is most dominance influencing respiration problem iilness occurrence among children under five years old are usage of fuel for cooking and children under tive years old who are out of house. Children under tive years old who are out of house have risk of respiration problem illness 2,59 times compared with children under five years old who are at house for long time, and also usage of fuel for cooking which became smoke has risk 2,32 times of reqriration problem illness compared with usage of Riel for cooking which did not become smoke (gas and electricity). 6). Probability of respiration problem illness occurrence among children under tive years old where they used fuel which will become smoke at their house and children under five years oId who have habit out of house 83,5 %. 7). Children under five years old who used fuel for cooking which became smoke (wood, charcoal and kerosene) and many activities of children under tive years old out of house have probabiiity of respiration problem illness occurrence 1,5 times bigger than children under five years old which used fuel for cooking which did not become smoke (gas and electrics) and many activities of children under five years old out of house.