Abstrak: ABSTRAK Nama : Wendy Primadhani Program Studi : Kajian Administrasi Rumah Sakit Judul : Faktor-faktor Yang Mempengaruhi Kepatuhan Perawat Pelaksana Terhadap Pelaksanaan Program Pengendalian dan Pencegahan Infeksi di RSUD Banyuasin Tahun 2016 Penelitian ini bertujuan mendapatkan gambaran kepatuhan perawat pelaksana di RSUD Banyuasin dalam pelaksanaan program pencegahan dan pengendalian infeksi, meneliti hubungannya dengan faktor predisposisi, penguat dan pemungkin dan juga perbedaan pengetahuan dan sikap serta persepsi keperawatan. Penelitian menggunakan metode campuran kuantitatif kualitatif dengan rancangan cross sectional. Data primer melalui observasi langsung dan pengisian kuesioner oleh perawat pelaksana. Faktor yang diukur adalah umur, lama kerja, kebijakan, tim PPI, dukungan atasan, motivasi teman sekerja, insentif, komitmen manajemen, pengetahuan, sikap, Standar Prosedur Operasional, sarana penunjang. Analisis data menggunakan uji Chi Square dan regresi logistik. Sampel penelitian sebanyak 30 responden, 16,7% perawat pelaksana memiliki kepatuhan yang baik dalam pelaksanaan program pencegahan dan pengendalian infeksi. Kesesuaian insentif merupakan faktor yang paling berpengaruh. Komitmen manajemen dan pengetahuan merupakan faktor yang berhubungan dengan kepatuhan perawat pelaksana. Saran untuk rumah sakit untuk memberikan pelatihan mengenai kewaspadaan standar, pemberian reward bagi perawat pelaksana yang giat melaksanakan PPI dan perubahan aturan pemerintahan. Kata Kunci : Program PPI, Kepatuhan perawat pelaksana ABSTRACT THE CONFORMANCE AMONG NURSING STAFF DUE TO INFECTION PREVENTION PROGRAM IN BANYUASIN HOSPITAL 2016 Wendy Primadhani1, Bachtiar A2 1 General Surgeon Department of Banyuasin Hospital, South Sumatera 2 Public Health Faculty , University of Indonesia Background: Healthcare-associated infection (HCAI) is a major problem for patient safety and its surveillance and prevention must be a first priority for settings and institutions committed to making health care safer. Human behavior and infection prevention and control are two areas that are linked. Aims: This study analyze factors that influence conformance infection prevention program among nursing staff. Methods: A cross-sectional study using mix method explanatory sequential strategy to nursing staff with simple random sampling undertaken in type C hospital in Banyuasin, South Sumatera. Data was collected using questionnaire and focus group discussion to respondent assessing factors that contribute to conformance among nursing staff and continue with in depth interview to hospital management. Results: About 30 nursing staff participated in the study, mean of age 29,50  5,355, working experience 4,60  2,328. The majority of nursing staff had poor (under 85% cut off point) conformance level (83,3%) using direct observation and the commitment of the hospital management, salaries and knowledge influences the conformance level. From focus group discussion shows that low salaries, lack of continuing education and availability of prevention control material also affect the conformance nursing staff. Conclusion: Our study results that poor conformance among nursing staff to infection prevention program is influenced by knowledge, hospital management and low salaries. The study alarms the needs to change the regent rule about salaries, hospital management should training the nursing staff, and material availability that can improve the quality of nursing staff. Keyword : infection prevention programme, nursing staff conforman