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Betty Tamanampo; Pembimbing: Caroline Endah Wuryaningsih
S-1810
Depok : FKM UI, 2000
S1 - Skripsi   Pusat Informasi Kesehatan Masyarakat
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Steven C. Moore, Wong-Ho Chow, Arthur Schatzkin, Kenneth F. Adams, Yikyung Park, Rachel Ballard-Barbash, Albert Hollenbeck, and Michael F. Leitzmann
Abstrak: Evidence for a relation between physical activity and renal cell cancer has been inconsistent. The authors examined physical activity in relation to renal cell cancer in a large, prospective US cohort study of 482,386 participants (289,503 men and 192,883 women) aged 50–71 years at baseline (1995–1996). At baseline, participants reported their frequency of exercise of at least 20 minutes' duration, intensity of daily routine activity, and frequency of physical activity during adolescence. During 8.2 years of follow-up (through December 2003), 1,238 cases of renal cell cancer were ascertained. In multivariate Cox regression models adjusted for renal cell cancer risk factors, the authors observed that current exercise, routine physical activity, and activity during adolescence were associated with a reduced risk of renal cell cancer. The multivariate relative risks for the highest activity level as compared with the lowest were 0.77 (95% confidence interval (CI): 0.64, 0.92; ptrend = 0.10) for current exercise, 0.84 (95% CI: 0.57, 1.22; ptrend = 0.03) for routine physical activity, and 0.82 (95% CI: 0.68, 1.00; ptrend = 0.05) for activity during adolescence. The authors conclude that increased physical activity, including activity during adolescence, is associated with reduced risk of renal cell cancer.
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AJE Vol.168, No.2
[s.l.] : [s.n.] : 2008
Indeks Artikel Jurnal-Majalah   Pusat Informasi Kesehatan Masyarakat
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Nisha Bansal ... [et al.]
AJE Vol.178, No.3
Oxford : Oxford University Press, 2013
Indeks Artikel Jurnal-Majalah   Pusat Informasi Kesehatan Masyarakat
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Sara Karami, Sarah E. Daugherty, Sara J. Schonfeld, Yikyung Park, Albert R. Hollenbeck, Robert L. Grubb, Jonathan N. Hofmann, Wong-Ho Chow, Mark P. Purdue
Abstrak: Clinical and experimental findings suggest that female hormonal and reproductive factors could influence kidney cancer development. To evaluate this association, we conducted analyses in 2 large prospective cohorts (the National Institutes of Health-AARP Diet and Health Study (NIH-AARP), 1995-2006, and the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO), 1993-2010). Cohort-specific and aggregated hazard ratios and 95% confidence intervals relating reproductive factors and kidney cancer risk were computed by Cox regression. The analysis included 792 incident kidney cancer cases among 283,952 postmenopausal women. Women who had undergone a hysterectomy were at a significantly elevated kidney cancer risk in both NIH-AARP (hazard ratio = 1.28, 95% confidence interval: 1.09, 1.50) and PLCO (hazard ratio = 1.41, 95% confidence interval: 1.06, 1.88). Similar results were observed for both cohorts after analyses were restricted to women who had undergone a hysterectomy with or without an oophorectomy. For the NIH-AARP cohort, an inverse association was observed with increasing age at menarche (P for trend = 0.02) and increasing years of oral contraceptive use (P for trend = 0.02). No clear evidence of an association with parity or other reproductive factors was found. Our results suggest that hysterectomy is associated with increased risk of kidney cancer. The observed associations with age at menarche and oral contraceptive use warrant further investigation.
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AJE Vol.177, No.12
Oxford : Oxford University Press, 2013
Indeks Artikel Jurnal-Majalah   Pusat Informasi Kesehatan Masyarakat
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Delima ... [et al.]
BPK Vol.45, No.1
Jakarta : Balitbangkes Depkes RI, 2017
Indeks Artikel Jurnal-Majalah   Pusat Informasi Kesehatan Masyarakat
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Karina Adristi Sasmitaningrum; Pembimbing: Kemal Nazarudin Siregar; Penguji: Popy Yuniar, Umi Zakiati
Abstrak:

Penyakit ginjal kronis merupakan penyebab kematian nomor 12 pada tahun 2017 dan diprediksi menjadi penyebab kematian nomor 5 pada tahun 2040. Berdasarkan data SKI 2023, prevalensi penyakit ginjal kronis di Indonesia adalah 0,18%. Walaupun relatif relatif kecil, masalah yang dihadapi adalah deteksi dini risiko dari faktor risiko penyakit ginjal kronis. Permasalahan penanganan penyakit ginjal kronis di Indonesia adalah kurangnya edukasi mengenai deteksi dini penyakit ginjal kronik serta faktor risikonya kepada masyarakat. Berdasarkan permasalahan ini, dilakukan penelitian untuk melihat faktor-faktor penyebab ginjal kronis di Indonesia. Penelitian dilakukan dengan menggunakan data SKI 2023 dengan jumlah sampel sebanyak 22639 individu. Penelitian ini dilakukan dengan uji kai kuadrat dan dilanjutkan dengan regresi logistik. Dari hasil regresi logistik yang dilakukan didapatkan hasil bahwa variabel yang menjadi faktor terbesar penyebab penyakit ginjal kronis adalah diabetes ( p-value = 0,008 ; OR = 4.792 (1,52-15,14)). Karena hasil penelitian menunjukkan diabetes sebagai faktor terbesar penyebab penyakit ginjal kronis, maka peneliti menyarankan bahwa terdapat dua fokus kebijakan yang dapat dilakukan. Pertama untuk penderita diabetes dalam hal pengontrolan penyakit, dan kedua kepada orang sehat dalam hal skrining dan deteksi dini serta promosi kesehatan untuk penerapan pola hidup sehat.


Chronic kidney disease was the 12th leading cause of death in 2017 and is predicted to be the  fifth leading cause of death in 2040. Based on SKI 2023 data, the prevalence of chronic  kidney disease in Indonesia is 0.18%. Although relatively small, the problem faced is early  detection of the risk of chronic kidney disease risk factors. The problem of handling chronic  kidney disease in Indonesia is the lack of education regarding the early detection of chronic  kidney disease and its risk factors to the community. Based on this problem, a study was  conducted to see the factors causing kidney chronicity in Indonesia. The study was conducted  using SKI 2023 data with a sample size of 22,639 individuals. This study was conducted  using the chi-square test and continued with logistic regression. From the results of the  logistic regression, it was obtained that the variable that was the most significant factor  causing chronic kidney disease was diabetes (p-value = 0.008; OR = 4.792 (1.52-15.14)).  Because the results of the study showed diabetes as the most significant factor causing  chronic kidney disease, the researcher suggested that there were two policy focuses that could  be implemented. Firstly, for people with diabetes in terms of disease control, and secondly,  for healthy people in terms of screening and early detection as well as health promotion for  implementing a healthy lifestyle. 

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S-11873
Depok : FKM UI, 2025
S1 - Skripsi   Pusat Informasi Kesehatan Masyarakat
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Fahrul Islam; Pembimbing: Budi Hartono, Laila Fitria; Penguji: Ririn Arminsih Wulandari, Didik Supriyono, Sonny Priajaya Warouw
Abstrak: Kromium adalah logam berat yang banyak digunakan dalam kegiatan industri.Penggunaan kromium pada industri pelapisan logam dapat berisiko terhadap kesehatanpekerja yang berasal dari pajanan kromium di udara lingkungan kerja. Penelitian inibertujuan untuk menganalisis hubungan kadar kromium dalam urin dengan kadaralbumin dalam urin sebagai biomarker kerusakan ginjal. Penelitian ini dilakukan pada33 pekerja terpajan dan 33 pekerja tidak terpajan dengan sedain cross sectional. Sampelurin diambil untuk menilai kadar kromium dan kadar albumin. Kadar kromium dalamurin diukur menggunakan metode metode Atomic Absorption Spectrometry (AAS)dengan teknik pembakaran (flame, FAAS) dan kadar albumin dalam urin di ukurdengan cara immunoturbidimetric assay. Nilai tengah (median) kadar kromium dalamurin pada pekerja terpajan sebesar 5 μg/L dan pada pekerja tidak terpajan juga sebesar5 μg/L. Nilai tengah (median) kadar albumin dalam urin pada pekerja terpajan sebesar2,5 mg/g kreatinin lebih tinggi dari kadar albumin pada pekerja tidak terpajan yaitusebesar 1,5 mg/g kreatinin. Setiap kenaikan kadar kromium 1 μg/L terjadi kenaikankadar albumin sebesar 3,82 mg/g kreatinin setelah dikontrol variabel riwayat diabetes,riwayat hipertensi, kebiasaan merokok, lama kerja, dan konsumsi alkohol. Hasilpenelitian dapat disimpulkan ada pengaruh pajanan kromium dengan gangguan fungsiginjal (p > 0,05).Kata kunci; albumin, kerusakan ginjal, kromium, pelapisan logam
Chromium is a heavy metal that is widely used in industrial activities. Use of chromiumin the metal plating industry pose a risk to workers' health comes from exposure tochromium in the air working environment. This study aimed to analyze the relationshipbetween chromium levels in urine levels of albumin in the urine as a biomarker ofkidney damage. This study was conducted on 33 workers exposed and 33 unexposedworkers with cross sectional sedain. Urine samples were taken to assess levels ofchromium and albumin. Chromium levels in urine were measured using the methodAtomic Absorption Spectrometry (AAS) with burning techniques (flame, FAAS) andalbumin in urine is measured by means of immunoturbidimetric assay. A middle value(median) level of chromium in the urine of workers exposed at 5 g / L and theunexposed workers are also at 5 ug / L. A middle value (median) level of albumin inthe urine in workers exposed at 2.5 mg / g creatinine higher than the levels of albuminin the unexposed workers is equal to 1.5 mg / g creatinine. Any increase in thechromium content of 1 ug / L occurred rising levels of 3,82 mg albumin / g creatinineafter the controlled variable history of diabetes, history of hypertension, smokinghabits, length of employment, and consumption of alcohol. The results of this studyconcluded there was an effect of chromium exposure with impaired renal function (p>0.05).Keywords; albumin, kidney damage, chromium, electroplating.
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T-4628
Depok : FKM-UI, 2016
S2 - Tesis   Pusat Informasi Kesehatan Masyarakat
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Ridha Ulfah; Pembimbing: Syahrizal; Penguji: Trisari Anggondowati, Felly Philipus Senewe
Abstrak: Lebih dari 16% populasi dunia dipengaruhi oleh penyakit ginjal kronis (PGK), dimana 19,3% akan berkembang menjadi Penyakit Ginjal Tahap Akhir (PGTA) dengan angka mortalitas 50% dalam 24 bulan. Prognosis yang buruk dan memerlukan biaya perawatan yang tinggi pada PGTA sehingga diperlukan pengkajian mengidentifikasi faktor-faktor yang menyebabkan insidensi PGTA. Penelitian ini bertujuan untuk mengidentifikasi determinan yang behubungan dengan kejadian PGTA di RSUD dr. Soedarso Kota Pontianak. Penelitian kuantitatif ini merupakan studi analitik case control menggunakan data primer wawancara dan rekam medis pasien selama bulan Mei – Juni 2023. Analisis regresi logistik berganda dilakukan untuk mengetahui determinan terhadap kejadian PGTA. Hasil analisis multivariat menunjukkan terdapat empat variabel yang berhubungan dengan kejadian PGTA, diantaranya: Hipertensi (OR 5,54, 95% CI: 2,59 – 11,80), Diabetes Melitus (OR 4,24, 95% CI: 1,79 – 9,98), riwayat keluarga PGK (OR 4,37, 95% CI: 1,02 – 18,73), merokok 10 batang/hari (OR 1,44, 95% CI: 0,56 – 3,74). Faktor prediktor dominan kejadian PGTA adalah variabel hipertensi. Penapisan yang lebih ketat berupa pemeriksaan laboratorium kadar kreatinin dan protein urin tiap satu tahun sekali diperlukan untuk mendeteksi PGK stadium awal, terutama pada pasien berisiko tinggi yang memiliki riwayat Hipertensi, Diabetes Melitus, riwayat keluarga PGK, dan merokok serta mengontrol penyakit komorbid untuk mencegah terjadinya PGTA.


More than 16% of the world's population is affected by chronic kidney disease (CKD), of which 19.3% will develop End Stage Kidney Disease (ESRD). It has a poor prognosis and requires high costs therapy, so its need to identify the factors that cause the incidence of ESRD. This study aims to identify the determinants associated with the incidence of ESRD in RSUD Dr. Soedarso Pontianak City. This quantitative research is an analytic case control study using primary data from interviews and medical records of patients from May to June 2023. Multiple logistic regression analysis was carried out to determine the determinants of the incidence of ESRD. The results of the multivariate analysis showed that there were four variables associated with the incidence of ESRD, including: Hypertension (OR 5.54, 95% CI: 2.59 – 11.80), Diabetes Mellitus (OR 4.24, 95% CI: 1.79 – 9.98), family history of CKD (OR 4.37, 95% CI: 1.02 – 18.73), smoking 10 cigarettes/day (OR 1.44, 95% CI: 0.56 – 3.74). The dominant predictor factor for the incidence of ESRD is hypertension. More stringent screening in the form of laboratory tests for urine protein and creatinine levels every once a year is needed to detect the early stages of CKD, especially in high-risk patients who have a history of Hypertension, Diabetes Mellitus, a family history of CKD, and smoking and to control comorbidities to prevent ESRD.
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T-6747
Depok : FKM-UI, 2023
S2 - Tesis   Pusat Informasi Kesehatan Masyarakat
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Savira Zain Laeli; Pembimbing: Pujiyanto; Penguji: Wachyu Sulistiadi, Laksmi Damaryanti
Abstrak:
Gagal Ginjal Kronik merupakan penyakit katastropik yang progresif dan irreversible dengan beban biaya tinggi dalam program Jaminan Kesehatan Nasional (JKN). Penelitian ini bertujuan untuk melihat gambaran biaya serta faktor-faktor yang mempengaruhi biaya pelayanan kesehatan penyakit GGK di Provinsi DKI Jakarta Tahun 2023. Penelitian ini menggunakan desain studi non-eksperimental kuantitatif yang dengan data sekunder dari data sampel BPJS Kesehatan tahun 2024. Analisis dilakukan secara univariat dan bivariat non-parametrik menggunakan uji Spearman, Mann-Whitney, dan Kruskal wallis dengan total sampel sebanyak 22.619 peserta. Hasil penelitian menunjukkan bahwa total beban biaya pelayanan GGK di DKI Jakarta tahun 2023 sebesar Rp555.265.832.525 dengan biaya per peserta sebesar Rp3.250.400. Variabel jenis kelamin laki-laki, usia 15-59 tahun, status perkawinan belum kawin, segmentasi kepesertaan PBI APBN, hak kelas rawat II, frekuensi RJTL, frekuensi RITL, dan lama hari rawat memiliki hubungan atau perbedaan median yang signifikan terhadap biaya pelayanan kesehatan (p-value<0,001). Kesimpulannya, seluruh variabel yang diteliti menunjukkan hubungan atau perbedaan median yang signifikan terhadap biaya pelayanan kesehatan penyakit GGK pada peserta JKN di Provinsi DKI Jakarta tahun 2023.


Chronic Kidney Disease (CKD) is a progressive and irreversible catastrophic illness with a high financial burden in the National Health Insurance (JKN) program. This study aims to describe the cost and identify factors affecting healthcare costs for CKD services among JKN participants in DKI Jakarta Province in 2023. This research employed a non-experimental quantitative design using secondary data from the 2024 BPJS Kesehatan sample dataset. Data were analyzed using univariate and non-parametric bivariate tests, including Spearman, Mann-Whitney, and Kruskal-Wallis tests, with a total sample of 22,619 participants. The results showed that the total healthcare expenditure for CKD in DKI Jakarta in 2023 was IDR 555,265,832,525, with an average cost per participant of IDR 3,250,400. The variables of male gender, age 15–59 years, unmarried status, PBI APBN membership segment, class II inpatient rights, frequency of outpatient and inpatient visits, and length of stay were significantly associated with differences in healthcare costs (p-value < 0.001). In conclusion, all studied variables showed a statistically significant relationship or difference in median costs for CKD healthcare services among JKN participants in DKI Jakarta in 2023.
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S-12034
Depok : FKM UI, 2025
S1 - Skripsi   Pusat Informasi Kesehatan Masyarakat
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Savira Zain Laeli; Pembimbing: Pujiyanto; Penguji: Wachyu Sulistiadi, Laksmi Damaryanti
Abstrak:
Gagal Ginjal Kronik merupakan penyakit katastropik yang progresif dan irreversible dengan beban biaya tinggi dalam program Jaminan Kesehatan Nasional (JKN). Penelitian ini bertujuan untuk melihat gambaran biaya serta faktor-faktor yang mempengaruhi biaya pelayanan kesehatan penyakit GGK di Provinsi DKI Jakarta Tahun 2023. Penelitian ini menggunakan desain studi non-eksperimental kuantitatif yang dengan data sekunder dari data sampel BPJS Kesehatan tahun 2024. Analisis dilakukan secara univariat dan bivariat non-parametrik menggunakan uji Spearman, Mann-Whitney, dan Kruskal wallis dengan total sampel sebanyak 22.619 peserta. Hasil penelitian menunjukkan bahwa total beban biaya pelayanan GGK di DKI Jakarta tahun 2023 sebesar Rp555.265.832.525 dengan biaya per peserta sebesar Rp3.250.400. Variabel jenis kelamin laki-laki, usia 15-59 tahun, status perkawinan belum kawin, segmentasi kepesertaan PBI APBN, hak kelas rawat II, frekuensi RJTL, frekuensi RITL, dan lama hari rawat memiliki hubungan atau perbedaan median yang signifikan terhadap biaya pelayanan kesehatan (p-value<0,001). Kesimpulannya, seluruh variabel yang diteliti menunjukkan hubungan atau perbedaan median yang signifikan terhadap biaya pelayanan kesehatan penyakit GGK pada peserta JKN di Provinsi DKI Jakarta tahun 2023.


Chronic Kidney Disease (CKD) is a progressive and irreversible catastrophic illness with a high financial burden in the National Health Insurance (JKN) program. This study aims to describe the cost and identify factors affecting healthcare costs for CKD services among JKN participants in DKI Jakarta Province in 2023. This research employed a non-experimental quantitative design using secondary data from the 2024 BPJS Kesehatan sample dataset. Data were analyzed using univariate and non-parametric bivariate tests, including Spearman, Mann-Whitney, and Kruskal-Wallis tests, with a total sample of 22,619 participants. The results showed that the total healthcare expenditure for CKD in DKI Jakarta in 2023 was IDR 555,265,832,525, with an average cost per participant of IDR 3,250,400. The variables of male gender, age 15–59 years, unmarried status, PBI APBN membership segment, class II inpatient rights, frequency of outpatient and inpatient visits, and length of stay were significantly associated with differences in healthcare costs (p-value < 0.001). In conclusion, all studied variables showed a statistically significant relationship or difference in median costs for CKD healthcare services among JKN participants in DKI Jakarta in 2023.
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S-12087
Depok : FKM UI, 2025
S1 - Skripsi   Pusat Informasi Kesehatan Masyarakat
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