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Widely use of ARV as treatment in people living with HIV has giving better life expectancy. Weconducted a retrospective cohort study to analyze 3 years survival time and associated factors among480 patients with HIV/AIDS who received ARV in 8 Public Health Center at West Jakarta. KaplanMeier and Cox Proportion hazard regression were used to calculate the survival time and itsassociated factors, respectively. The cumulative survival rates of those receiving ARV in 1,2 and 3years were 95,2%, 91,7% and 78,3%. Multivariate Cox Regression analysis showed that patients withTB-coinfection were at a higher risk of death from AIDS-related diseases (HR = 2,621; 95%CI:1,027-6,407, nilai P = 0,035) than patients without TB-coinfection. Patients with ARV adherence<95% were at a higher risk of death from AIDS-related diseases (HR = 9,298; 95%CI: 4,633-18,660,nilai P = 0,000) than patients with adherence ≥95%.Key words:HIV, ARV, survival.
The survival of HIV/AIDS patients is strongly influenced by the timing of antiretroviral therapy (ART) initiation following diagnosis. This study aimed to analyze the relationship between the ART initiation period and three-year survival among HIV/AIDS patients in Bekasi District. A retrospective cohort design was used, based on secondary data from the HIV/AIDS Information System (SIHA) of Bekasi District, involving patients diagnosed with HIV/AIDS during the 2017–2022 period. A total of 1,554 patients met the inclusion criteria. Kaplan-Meier analysis was employed to estimate survival probability, while time-dependent Cox regression analysis was used to assess the effect of ART initiation timing on the risk of death, controlling for sociodemographic, clinical, treatment-related, and behavioral variables. The results showed that the highest survival was observed among patients who initiated ART within
The number of new HIV infections in Indonesia is still high, reaching 46,000 and number of deaths caused by HIV is 38,000 in 2018. Hepatitis C coinfection in HIV patients is high, ranging from 2-15%. This study aims to examine the effect of hepatitis C coinfection on survival of HIV patients receiving antiretroviral therapy at Tebet Regional Public Hospital (RSUD) in 2015-2020. This research used retrospectif cohort design with survival analysis and used total sampling as much as 284 HIV patients. Data were analyzed univariately to see the frequency distribution of each variable studied. Bivariate analysis was performed to see the relationship of each independent variable with the survival of HIV. Multivariate analysis was performed to obtain robust and parsimonius models with Cox Regression. The results of research found cumulatif survival of HIV patients in RSUD Tebet were 85,4 %. The Effect of Hepatitis C Coinfection on Survival HIV Patients Who Receive Antiretroviral Therapy in RSUD Tebet from 2015 until 2020 had HR 1,94 (95% CI 0,81-4,6) after adjusted with body mass index and working status. There were no corelation from Hepatitis C Coinfection on Survival HIV Patients Who Receive Antiretroviral Therapy in RSUD Tebet from 2015 until 2020.
Human Immunodeficiency Virus (HIV) is still an issue in health sector in the world, particularly in Indonesia. Progression of disease is influenced by various factors including age, genetic, and other infectious diseases such as tuberculosis and hepatitis, nutritional factors, and immunological status. ARV therapy has not been able to cure the disease yet is able to control the progression of HIV/AIDS by suppressing viral replication which reduce the incidence of opportunistic infections. Although the program has been implemented, the deaths from HIV continue to occur, especially in the first year of ARV treatment. This study aims to investigate the predictors related to death in HIV-AIDS patients with ARV therapy in Dr. H. Marzoeki Mahdi Hospital in Bogor in 2008-2012. The study design was retrospective cohort using ART registration data and Medical Record. Number of samples were 396 HIV patients with ARV therapy. Data analysis was performed using Cox Regression. The multivariate analysis showed that the predictors of deaths in HIV-AIDS patients with ARV therapy were functional baring status (RR = 2.34, 95% CI: 1.32-4.11), heavy IO category (RR = 2.11, 95% CI : 1.26-3.54), and anemia status (RR = 2.56, 95% CI: 1.74-3.77). Special attention and monitoring are required for HIV/AIDS patients taking antiretroviral medications with functional status of baring, anemia, and having severe opportunistic infections. Keywords: ARV; HIV-AIDS; Retrospective cohort; Death; Predictors.
