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Stroke is the third disease which often cause death in Indonesia. Prevalence of stroke in Indonesia from Riskesdas 2007 is 8,3 per 1000 person. Prevalence of stroke in Jakarta is still higher then national prevalence that is 12,5 per 1000 person and cause a lot of problems both in terms of social and economic. This research aims to identify different risk factors of ischemic and hemorragic stroke in inpatient of stroke at National Cardiovascular Center Harapan Kita 2012. The study was conducted by analyzing secondary data from patient medical record by using cross sectional study. Results showed that there were patients with ischemic stroke (10,4%) and hemorrhagic (89,6) with a characteristic age ≥62 years (51,5%), male (62%), low education (17,8%), smoking behaviour (37,4%), hypertension (81,6%) and diabetes (50,3%). Based on bivariate analysis, result shows that there is no statistical difference between risk factors and incidence of stroke, but the difference proportion of risk factors in ischemic stroke always greater than hemorrhagic stroke.
ABSTRAK Nama : Anna Mardiana Ritonga Program Studi : Epidemiologi Judul : Faktor-Faktor yang Mempengaruhi Mortalitas Pasien Stroke Associated Pneumonia di Stroke Care Unit Rumah Sakit Pusat Otak Nasional Tahun 2016-2018 Pembimbing : dr. Syahrizal Syarif, MPH, Ph.D Stroke Associated Pneumonia (SAP) adalah komplikasi stroke yang paling sering terjadi dan memiliki angka mortalitas yang tinggi. Faktor-faktor yang mempengaruhi mortalitas pasien SAP belum sepenuhnya diselidiki. Pengetahuan tentang faktor-faktor yang mempengaruhi mortalitas dapat membantu pengambilan keputusan klinis untuk tatalaksana pasien. Penelitian ini bertujuan untuk mengetahui faktor-faktor yang mempengaruhi mortalitas pasien SAP yang dirawat di Stroke Care Unit (SCU) Rumah Sakit Pusat Otak Nasional (RSPON) tahun 2016-2018. Desain penelitian ini adalah penelitian kohort retrospektif, pada 268 pasien di SCU RSPON yang didiagnosis SAP selama tahun 2016-2018. Variabel yang berhubungan bermakna dengan mortalitas pada pasien SAP adalah kesesuaian LOS dengan CP RSPON, didapatkan risiko 0,262 (95% CI : 0,138 – 0,501) yang berarti pasien dengan Length of Stay (LOS) tidak sesuai dengan Clinical Pathway (CP) RSPON memiliki hubungan protektif terhadap mortalitas pasien SAP yaitu sebesar 0,26 kali. Dengan menggunakan model prediktor, dapat dihitung probabilitas terjadinya mortalitas pada pasien SAP. Kata kunci: kohort retrospektif; mortalitas; Stroke Associated Pneumonia
ABSTRACT Name : Anna Mardiana Ritonga Study Program : Epidemiology Title : Determining Factors for Stroke Associated Pneumonia Mortality in the Stroke Care Unit National Brain Centre Hospital 2016-2018 Counsellor : dr. Syahrizal Syarif, MPH, Ph.D Stroke Associated Pneumonia (SAP) is the most common complication after stroke and has a high mortality rate. Determining factors for SAP mortality have not been fully investigated. Knowledge of its determining factors can help clinical decision making for patient management. The aim of this study was to determine the mortality factors of SAP who were treated in the Stroke Care Unit (SCU) National Brain Centre (NBC) Hospital. This study used retrospective cohort design, involving 268 subjects SAP obtained at SCU NBC who were diagnosed with SAP during 2016-2018. Variable that significantly related is suitability of Length of Stay (LOS) with Clinical Pathway (CP) NBC obtained the risk of 0.262 (95%CI : 0,138-0,501) which means has protective association with mortality. By using a predictor model, it can be calculated the probability of mortality in SAP patients. Keywords: mortality; retrospective cohort; Stroke Associated Pneumonia
Citicoline is the most widely used neuroprotective to repair neurological deficit inischemic stroke patients, however the effectiveness of citicoline is stillcontroversial and raise arguments against scientific research because it providedheterogeneous results.The objectives of the study are to identify citicoline effecton neurological function improvement using The National Institute of HealthStroke Scale (NIHSS) and functional ability improvement using Barthel Index(BI) in the treatment of ischemic stroke patients at 18 hospitals involved inIndonesia stroke registry. The design of this study is retrospective cohort studyusing stroke registry data. Improvement of neurological function assessed bychanges of NIHSS score >2 and improvement of functional ability assesed bychanges of Barthel Index score > 20 as measured at the time of admission anddischarge of the hospital.The result shows that the probability of functionalneurological improvement on citicoline treatment group is higher than nociticoline treatment group with adjusted RR by neurorestoration is 1,34 (95% CI1.058 to 1.658, p=0,0014). There is no difference of functional abilityimprovement between citicoline and no citicoline treatment group, with adjustedRR by neurorestoration is 1.07 (CI95% 0.879 to 1.293; p=0,53).Keywords : Barthel Index; Citicoline; Ischemic stroke; NIHSS.
Karsinoma endometrium merupakan salah satu keganasan yang menyerang wanita dengan angka kesintasan yang relatif baik. Salah satu faktor yang diduga berperan dalam prognosis karsinoma endometrium antara lain adalah usia saat diagnosis. Penelitian ini bertujuan untuk melihat hubungan usia saat diagnosis dengan kesintasan hidup keseluruhan pasien 4 tahun karsinoma endometrium yang dirawat di RS Kanker Dharmais selama rentang tahun 2013–2019.
Studi ini merupakan kohort retrospektif yang menggunakan data sekunder berupa regsitri kanker berbasis rumah sakit dan sistem informasi RS di RSKD dengan subjek data pasien karsinoma endometrioid endometrium yang terdiagnosis dalam rentang 2013-2019. Sebanyak 220 pasien eligibel untuk dilakukan analisis terhadap variabel usia saat diagnosis, stadium, derajat keganasan, durasi menerima terapi, protokol terapi, kedalam invasi, adanya diabetes mellitus, hiperkolesterol, dan hipertensi. Analisis statistik digunakan untuk melihat hubungan masing-masing variabel terhadap kesintasan hidup, interaksi antar variabel, dan adanya perancu. Model akhir dibangun untuk melihat perbedaan kesintasan hidup pasien berdasarkan usia.
Probabilitas kesintasan hidup pada pasien karsinoma endometrium dirawat di RS Kanker Dharmais adalah 78,19%. Tidak terdapat perbedaan pada probabilitas kesintasan karsinoma endometrium pada kelompok usia ≥50 tahun (74,91%) dan
Endometrial endometrioid carcinoma is one of the malignancies that affect women with relatively excellent survival rates. One of the factors that play a role in the prognosis of endometrial carcinoma is the age at diagnosis. This study aims to examine the corellation between age at diagnosis and 4 years overall survival of endometrial carcinoma patients treated at Dharmais National Cancer Hospital from 2013 to 2019. This study was a retrospective cohort that utilized secondary data from the hospital-based cancer registry and the hospital information system at Dharmais National Cancer Hospital, involving subjects diagnosed with endometrioid endometrial carcinoma between 2013 and 2019. A total of 220 eligible patients were analyzed for variables such as age at diagnosis, stage, grade of malignancy, duration of treatment, treatment protocol, depth of invasion, presence of diabetes mellitus, hypercholesterolemia, and hypertension. Statistical analysis was used to assess the relationship between each variable and overall survival, interaction between variables, and confounding factors. A final model was constructed to examine the difference in survival among patients based on age at diagnosis. The survival probability for endometrial endometrioid carcinoma at Dharmais Cancer Hospital is 78.19%. There was no difference in the survival probability between the age groups ≥50 years (74.91%) and
