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Karsinoma endometrium merupakan salah satu keganasan yang menyerang wanita dengan angka kesintasan yang relatif baik. Salah satu faktor yang diduga berperan dalam prognosis karsinoma endometrium antara lain adalah usia saat diagnosis. Penelitian ini bertujuan untuk melihat hubungan usia saat diagnosis dengan kesintasan hidup keseluruhan pasien 4 tahun karsinoma endometrium yang dirawat di RS Kanker Dharmais selama rentang tahun 2013–2019.
Studi ini merupakan kohort retrospektif yang menggunakan data sekunder berupa regsitri kanker berbasis rumah sakit dan sistem informasi RS di RSKD dengan subjek data pasien karsinoma endometrioid endometrium yang terdiagnosis dalam rentang 2013-2019. Sebanyak 220 pasien eligibel untuk dilakukan analisis terhadap variabel usia saat diagnosis, stadium, derajat keganasan, durasi menerima terapi, protokol terapi, kedalam invasi, adanya diabetes mellitus, hiperkolesterol, dan hipertensi. Analisis statistik digunakan untuk melihat hubungan masing-masing variabel terhadap kesintasan hidup, interaksi antar variabel, dan adanya perancu. Model akhir dibangun untuk melihat perbedaan kesintasan hidup pasien berdasarkan usia.
Probabilitas kesintasan hidup pada pasien karsinoma endometrium dirawat di RS Kanker Dharmais adalah 78,19%. Tidak terdapat perbedaan pada probabilitas kesintasan karsinoma endometrium pada kelompok usia ≥50 tahun (74,91%) dan
Endometrial endometrioid carcinoma is one of the malignancies that affect women with relatively excellent survival rates. One of the factors that play a role in the prognosis of endometrial carcinoma is the age at diagnosis. This study aims to examine the corellation between age at diagnosis and 4 years overall survival of endometrial carcinoma patients treated at Dharmais National Cancer Hospital from 2013 to 2019. This study was a retrospective cohort that utilized secondary data from the hospital-based cancer registry and the hospital information system at Dharmais National Cancer Hospital, involving subjects diagnosed with endometrioid endometrial carcinoma between 2013 and 2019. A total of 220 eligible patients were analyzed for variables such as age at diagnosis, stage, grade of malignancy, duration of treatment, treatment protocol, depth of invasion, presence of diabetes mellitus, hypercholesterolemia, and hypertension. Statistical analysis was used to assess the relationship between each variable and overall survival, interaction between variables, and confounding factors. A final model was constructed to examine the difference in survival among patients based on age at diagnosis. The survival probability for endometrial endometrioid carcinoma at Dharmais Cancer Hospital is 78.19%. There was no difference in the survival probability between the age groups ≥50 years (74.91%) and
In the last 2019, COVID-19 as New Emerging Disease causing a pandemic rapidly.The numbers of health care workers infected COVID-19 worldwide until 8 th April 2020 in 52 countries were 22.073. 2 nd March 2020, Depok city report the first case confirmed COVID-19 also the first case in Indonesia. Limited research about risk of healthcare worker infected COVID-19 and some of the research only examine in healthcare worker group became this research base to assess the association of healthcare worker and confirmed case in Depok City. A crossectional study has been done using secondary data obtained from Epidemiological Investigation Form from MOH Guidelines in Health District Office in Depok. This study using data obtained inMarch- June 2020 involving 925 respondents.The results show that status of healthcare worker cannot stand alone in the association with confirmed case COVID-19. Noted combinationbetween history of contact with suspect COVID-19 and visiting health care facility among respondentas health care worker elevated risk 2,13 times become confirmation cases of COVID-19 (95% CI 1,33-3,41) also significantly related to confirmation case of COVID-19 in Depok City (p= 0,002)
In 2022, Indonesia ranked fourth globally in the number of breast cancer deaths. One of the contributing factors to the high mortality rate is comorbidity. This study aims to examine the association between comorbidities and three-year survival of breast cancer patients in Indonesia. A retrospective cohort design was used, involving 896 samples from the 2018–2023 BPJS Kesehatan General Sample Data. Survival curves and probabilities were estimated using the Kaplan-Meier method, while associations were analyzed using the log-rank test and Hazard Ratios (HR) via Cox regression. The study found that the cumulative survival probability (CSP) at 36 months for the overall sample was 49.9%, with a median survival time of 35,34 months. Breast cancer patients with comorbidities and other comorbid conditions had a higher risk of death within three years (comorbidity CSP = 43.7%; HR = 1.38; 95% CI = 1.01–1.89, other comorbidities CSP = 42.4%; HR = 1.43; 95% CI = 1.01–2.04). No significant differences in survival were found based on metabolic disorders including diabetes, hypertension, cardiovascular disease, age at diagnosis, marital status, socioeconomic status, or place of residence. Breast cancer survival in Indonesia remains low, particularly among patients with comorbidities.
