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Cervicitis is one of the Sexually Transmitted Infections (STIs). There is a correlation between socio-demographic development and migration with increase of the number of high-risk populations. WHO estimates there are 376 million new infections by 1 out of 4 STIs, such as chlamydia (127 million), gonorrhea (87 million), syphilis (6.3 million) and trichomoniasis (156 million). Gatot et al, showed that 11.9% of patients had cervicitis. Iskandar, et al, also showed the prevalence of cervical infections (chlamydia 9,3% and 1,2% gonorrhea). Based on the results of the SDKI, there had been an increasing trend in contraceptive use in Indonesia from 1991 to 2017. There was a statistically significant association between cervicitis and HPV infection. It will increase the risk of getting infected by HPV if cervicitis is left untreated. Additionally, a person with mucopurulent cervicitis symptoms has an increased risk of cervical cancer. This study aims to determine the relationship between the use of hormonal contraceptives and the incidence of cervicitis. This is a quantitative study with a cross sectional study design. This study used secondary data from the results of the VIA examination at the primary health care supervised by the Female Cancer Program (FcP) in DKI Jakarta in 2017-2019. The number of samples were 3563 people, who met the inclusion and exclusion criteria. This study used logistic regression to analyze the data. The prevalence of cervicitis in this study was 11.20%. There is a relationship between hormonal contraceptive use and the incidence of cervicitis which is statistically significant with p-value<0.0001. Thus, it is necessary to carry out periodic checks on women who use hormonal contraception to prevent cervicitis and cervical cancer.
Cervical cancer is commonly occurs in woman. More than 1.4 million ofwomen suffer from this disease.In Indonesia the Incidence Rate of cervical canceris 13/100.000 woman. The result of early detection cervical cancer program withIVA method in Karawang revealed 246 cases from 2010-2013. In 2014 until Junethere are 56 cases. The increasing of divorced rate (200 cases/year)andprostitutions di Karawang District are the risk factor of cervical cancer. Thepurpose of this research is to know the risk factor of changed sex partner towardscervical cancer in Karawang District.A case control study design was conducted with two controls per case. Thesource of data identified from public health centre register and confirmed casesfrom hospital register of Karawang during 2014. Information collected onparticipants using pretested questionnaires, during household interviews includedage, education level, occupation, income, family cervical cancer history, age offirst sex, smoking, using hormonal contraception, parity and consumption pattern.We estimated odds ratio (OR) and confidence interval (CI 95%) usingmultivariate logistic regression.Fifty-two cases and 104 controls were enrolled. The bivariate model ofchanging sex partner towards cervical cancer showed (OR: 3.57 CI 95%: 1.67-7.6). The multivariate model included age, level education, income, familycervical cancer history, smoking active and passive, parity, age of first time sex,using hormonal contraception, and food contain carcinogen consumption. Theodds ratio adjusted (OR adj : 2.68, CI 95%: 1.03-6.9). The variable of age, level ofeducation, family cervical cancer history, active smoking and using hormonalcontraception are the confounders in relation between changing sex partner withcervical cancer.Woman with changing sex partner behaviour were more likely to havecervical cancer 2.68 times compared with women who did not changing sexpartner. District Health office of Karawang should increasing the health campaignof the risk factor of cervical cancer and preventing cervical cancer with earlydetection in public health centre.Key words: cervical cancer, changing sex partner, case control study
ABSTRAK Nama : Hairida Anggun Kusuma Program Studi : Pascasarjana Ilmu Kesehatan Masyarakat Judul : Faktor-faktor yang Berhubungan dengan Kejadian Lesi Prakanker Serviks di Kabupaten Kotawaringin Timur Tahun 2017 Permasalahan kanker serviks di Indonesia sangat khas yaitu banyak dan lebih dari 70% kasus ditemukan pada stadium lanjut pada saat datang ke rumah sakit. Peningkatan upaya penanganan kanker serviks, terutama dalam bidang pencegahan dan deteksi dini sangat diperlukan oleh setiap pihak yang terlibat. Penelitian kasus kontrol ini bertujuan untuk mengetahui faktor risiko yang berhubungan dengan kejadian lesi prakanker serviks. Penelitian melibatkan 102 kasus dan 306 kontrol dari cacatan medis pemeriksaan deteksi dini kanker leher rahim dan payudara tahun 2013 – 2016. Penelitian di 11 puskesmas yang telah melaksanakan pemeriksaan IVA di Kabupaten Kotawaringin Timur. Analisis data dilakukan secara univariat, bivariat dengan chi square dan multivariat dengan regresi logistik ganda untuk mengetahui faktor yang paling dominan. Sebagian besar umur responden ≤35 tahun, pendidikan dasar, tidak bekerja, tidak mempunyai riwayat kanker, usia melakukan hubungan seksual >17 tahun, punya pasangan seksual satu, tidak pernah menggunakan kontrasepsi oral >5 tahun, paritas ≥4 dan tidak pernah pap smear. Sedangkan untuk paparan asap rokok sama besar antara yang terpapar dan tidak terpapar. Hasil regresi logistik ganda menemukan terpapar asap rokok dengan (OR 1,9 95% CI 1,1 – 3), riwayat kanker keluarga (OR 2,5 95% CI 1,3-4,6), paritas ≥4 (OR 2 95% CI 0,9 – 4,4) dan jumlah pasangan seksual lebih dari 1 (OR 1,5 95% CI 0,9 – 2,8) dan faktor yang paling dominan adalah riwayat kanker keluarga. Kata kunci: Lesi prakanker serviks; paparan asap rokok; riwayat kanker keluarga.
ABSTRACT Name : Hairida Anggun Kusuma Study Program : Postgraduate Public Health Faculty Title : Factors Related to Cervical Precancerous Lesions in East Kotawaringin District 2017 The problem of cervical cancer in Indonesia is very distinctive that many and more than 70% of cases are found at an advanced stage upon arrival to the hospital. Increased efforts to treat cervical cancer, especially in the field of prevention and early detection is needed by each party involved. This case-control study aims to determine risk factors associated with the incidence of cervical precancer lesions. The study included 102 cases and 306 controls derived from medical records examining early detection of cervical and breast cancers from 2013 to 2016. The study was at 11 puskesmas who had performed VIA examination in East Kotawaringin District. Data analysis was done univariat, bivariate with chi square and multivariate with logistic regression to know the most dominant factor. Most of the respondents aged ≤35 years, primary education, unemployment, no history of cancer, age of sexual intercourse >17 years, had one sexual partner, never used oral contraceptives >5 years, parity ≥4 and never pap smear. As for exposed by smoke as large between the exposed and not exposed. The result of logistic regression showed exposed to cigarette smoke (OR 1,9 95% CI 1,1 – 3), family cancer history (OR 2,5 95% CI 1,3-4,6), parity ≥4 (OR 2 95% CI 0,9 – 4,4) dan sexual multipartner (OR 1,5 95% CI 0,9 – 2,8) and the more dominant risk factor was family history of cancer. Keywords: cervical precancerous lesions;exposed by smoke; family history of cancer
