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Kata kunci : Kanker kolorektal, Matched case control, Faktor risiko
Colectal cancer disease is colon cancer and rectum until now is a health problem in the word, including in Indonesia yet. The purpose of this study is to investigate the risk factor and dominant factor of colorectal cancer. The design of study used was matched case control with age matching using the medical record data, the data of case were colorectal cancer patients and control were trauma and fracture patients. The calculate sample is 122 people were 61 pairs of cases and controls. The result of bivariate analysis of mc nemar chi square showed related risk factor was red meat diet with OR=27 (95% CI 4,45-1105,4), high fat intake with OR=2,2 (95% CI 0,967-5,542), and low fiber intake with OR=44 (95% CI 7,49- 1776,9). Multivariate analysis of conditional logistic regression showed the most important factor was low fiber intake with OR=26,8 (95% CI 3,448-209,5). The unrelated risk factors are gender, education level, family history, family income, physical activity, obesity, smoking and alcohol. It is necessary to prevent the prevention of colorectal cancer by increasing fiber intake, reducing fat intake and concumption pattern of read meat.
Keywords : Colorectal cancer, Matched case control, Risk factor
Seeing the high rate of pneumonia incidence in infant and unknown effect ofStaphylococcus sp bacteria as one of the bacteria causing pneumonia in indoor air, hencethere is need of research about relation of existence of Staphylococcus sp bacteria inindoor air with incidence of pneumonia in infant after controlled with confoundingvariable at infant in Bandar Lampung City in 2016. This research used pneumonia studydata by BBTKLPP Jakarta in 2016. The sample of research are 75 cases and 75 controlsfrom 6 sub districts in Bandar Lampung City. From the result of the research, it can beconcluded that there is a relationship between an existence of Staphylococcus sp bacteriain indoor air with the incidence of pneumonia in infants after controlled confoundingvariables in Bandar Lampung City (OR = 7,332 CI 95% 2,874-18,707) where the infantfound Staphylococcus sp bacteria in indoor air his home had a 7,332 times greater risk ofdeveloping pneumonia.Key words:Pneumonia, Infant, risk factors, case control.
PROGRAM PASCA SARJANA
PROGRAM STUDI ILMU KESEHATAN MASYARAKAT
BIOSTATISTIK
Tesis, 28 Juni 2013
Sasmin Itadi Suhanto
Peran dan Dampak Perilaku Pencegahan Gigitan Nyamuk Terhadap Kejadian Malaria di Kabupaten Kaur, Provinsi Bengkulu, tahun 2012
ABSTRAK
Malaria masih merupakan masalah kesehatan masyarakat walaupun berbagai usaha telah dilakukan untuk mencegahnya tetapi malaria masih ditemukan. Kabupaten Kaur termasuk daerah dengan endemisitas rendah dengan angka API< 1‰. Tujuan penelitian ini adalah untuk mengetahui gambaran, peran dan dampak perilaku pencegahan gigitan nyamuk serta faktor risiko lainnya terhadap kejadian malaria di Kabupaten Kaur tahun 2012. Penelitian ini menggunakan rancangan observasional dengan pendekatan case control study. Lokasi penelitian ini adalah seluruh wilayah kerja puskesmas yang ada dalam Kabupaten Kaur yaitu sebanyak 16 puskesmas. Dengan jumlah sampel sebanyak 264 orang dengan rincian 132 orang kasus dan 132 orang kontrol. Kasus adalah pengunjung yang datang ke rumah sakit, puskesmas dan jaringannya dengan gejala demam dengan hasil pemeriksaan sediaan darah di laboratorium atau RDT (Rapid Diagnostik Test) positif malaria. Kontrol adalah pengunjung yang datang ke rumah sakit, puskesmas dan jaringannya dalam tahun 2012 dengan gejala demam dan hasil pemeriksaan sediaan darah di laboratorium atau RDT (Rapid Diagnostik Test) menunjukan negatif malaria.
Hasil : Analisis multivariate menunjukan bahwa kebiasaan sering dan kadang-kadang begadang malam di luar rumah dengan nilai OR masing-masing sebesar 6,37 (95% CI 1,65–24,60) dan 1,84 (95% CI 0,72–4,71), kebiasaan sering dan kadang-kadang menggunakan kelambu dengan nilai OR masing-masing sebesar 0,1 (95% CI 0,004-0,05) dan 0.08 (95% CI 0.01-0,68), kebiasaan sering dan kadang-kadang menggunakan obat anti nyamuk bakar dengan nilai OR masing-masing sebesar 0,01 (95% CI 0,004-0,05) dan 0,75 (95% CI 0,12-4,79) dan kebiasaan sering dan kadang menggunakan obat anti nyamuk cair dengan nilai OR masing-masing sebesar 0,02 (95% CI 0,005-0,06) dan 0,06 (95% CI 0,004-0,997) berhubungan signifikan dengan kejadian malaria setelah dikontrol dengan langit-langit rumah. Sedangkan penggunaan kasa ventilasi tidak berhubungan signifikan dengan kejadian malaria. Hasil perhitungan dampak: kebiasaan sering begadang malam di luar rumah dapat menurunkan kasus kejadian malaria sebesar 19,1% jika dihentikan/ditiadakan, penggunaan kelambu 15,5%, penggunaan obat anti nyamuk (bakar dan cair ) masing-masing sebesar 32,7% dan 24% pada populasi.
Kesimpulan :
Perilaku pencegahan gigitan nyamuk seperti kebiasaan begadang malam di luar rumah, penggunaan kelambu, obat anti nyamuk (bakar dan cair/semprot) mempunyai perananan penting dalam kejadian malaria.
Kata kunci : Kejadian malaria, perilaku pencegahan gigitan nyamuk, case control.
PROGRAM MAGISTER
PUBLIC HEALTH SCIENCE PROGRAM
Biostatistics Thesis, June 28, 2013
Sasmin Itadi Suhanto
Role and Impact Behavior Mosquito Bite Prevention Against Malaria incidence in Kaur regency, Bengkulu province, in 2012
ABSTRACT
Malaria remains a public health problem despite efforts have been done to prevent it, but malaria is found. Kaur district includes areas with low endemicity with API numbers <1 ‰. The purpose of this study is to describe the role and impact of mosquito bite prevention behaviors and other risk factors on the incidence of malaria in the district Kaur in 2012. This study uses observational design of case control study. The study site is the working area of the existing health center in the district as many as 16 health centers Kaur. With a total sample of 264 people with the details of 132 cases and 132 controls. Case was the visitors who come to the hospital, health center and network with symptoms of fever with the results of blood clots in the laboratory or RDT (Rapid Diagnostic Test) positive malaria. Control was the visitors who come to the hospital, health centers and networks in the year 2012 with symptoms of fever and blood clots in the results of the laboratory examination or RDT (Rapid Diagnostic Test) showed a negative malaria.
Results: Multivariate analysis showed that the habit of frequent and sometimes stay up all night outside the house with a value amounting OR 6.37 (95% CI 1.65 to 24.60) and 1.84 (95% CI 0.72 - 4.71), and a frequent habit of sometimes using nets with OR values respectively of 0.1 (95% CI 0.004 to 0.05) and 0:08 (95% CI 0.01-0,68), and a frequent habit sometimes use anti mosquito OR at each value of 0.01 (95% CI from 0.004 to 0.05) and 0.75 (95% CI 0.12 to 4.79) and the habit of frequent and sometimes use anti mosquito liquid with each value OR of 0.02 (95% CI 0.005-0.06) and 0.06 (95% CI 0.004 to 0.997) significantly associated with the incidence of malaria after controlled ceiling. While the use of gauze vents are not significantly associated with the incidence of malaria. Results of impact assessment: the habit to stay up late at night outside the home can reduce the incidence of malaria cases by 19.1% if terminated / removed, 15.5% use of mosquito nets, mosquito drug use (fuel and liquid), respectively by 32.7% and 24% of the population.
Conclusion: Mosquito bite prevention behaviors such as staying up all night habits outside the home, the use of bed nets, anti mosquito (fuel and liquid / spray) have an important role in the incidence of malaria.
Keywords: incidence of malaria, a mosquito bite prevention behaviors, case control.
