Abstrak: Bahaya kebakaran dan ledakan di laboratorium mengunakan bahan kimia dapatmengakibatkan kematian, cacat, pencemaran, kehilangan aset, dan rusaknyareputasi. Penyebabnya adalah bahan kimia mudah menyala, mudah terbakar, mudahmeledak, dan bahan kimia phyrophoric. Untuk antisipasi bahaya tersebut perludibangun sistem proteksi kebakaran yang komprehensif di laboratorium. Risetdilakukan berdasarkan NFPA 45: 2015 yang merupakan standar sistem proteksikebakaran untuk laboratorium yang mengunakan bahan kimia pada laboratoriumPT. XYZ. Metoda yang digunakan adalah observasi, diskusi, dan pengisian daftarperiksa. Disini tujuannya adalah membandingkan standar NFPA 45:2015 denganpenerapan yang dilakukan selama ini. Dari hasil ini akan didapat rekomendasiketidaksesuaian yang akan dijadikan tindakan perbaikan dimasa yang akan datang.Kata Kunci: Laboratorium, NFPA 45, Sistem Proteksi Kebakaran, Bahan KimiaMudah Menyala, Bahan Kimia Mudah Terbakar.

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Hazard of fire and explosion in the laboratory using chemicals can result in death,disability, pollution, loss of assets, and loss to reputation. The cause is combustible,flammable chemic, explosive, and pyrophoric chemicals. To anticipate the dangersneed to be built a comprehensive fire protection system in the laboratory. Theresearch was conducted based on NFPA 45:2015 standard on fire protection systemfor laboratories using chemicals in the laboratory PT. XYZ. The method used inthis study is observation, discussion, and checklist developed. The aim is tocompare the standard of NFPA 30: 2015 by implementation made during it. Fromthese results will come by recommendation of a non-conform finding as correctiveactions in the future.Keywords: Laboratory, NFPA 45, Fire Protection, Flammable Chemicals,Combustible Chemicals

Abstrak: Hyperuricemia in children is associated with increased risk of high blood pressure, metabolic syndrome, and future cardiovascular disease. Serum perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) levels have been shown to be positively associated with hyperuricemia in adults, but the association in children remains unexplored. We therefore examined the association between serum PFOA and PFOS levels and hyperuricemia in a representative sample of US children. A cross-sectional study was performed on 1,772 participants ≤18 years of age from the National Health and Nutrition Examination Survey 1999-2000 and 2003-2008. The main outcome of interest was hyperuricemia, defined as serum uric acid levels ≥6 mg/dL. We found that serum levels of PFOA and PFOS were positively associated with hyperuricemia, independent of age, sex, race/ethnicity, body mass index, annual household income, physical activity, serum total cholesterol, and serum cotinine levels. Compared with subjects in quartile 1 (referent), subjects in quartile 4 had multivariable-adjusted odds ratios for hyperuricemia of 1.62 (95% confidence interval: 1.10, 2.37) for PFOA and 1.65 (95% confidence interval: 1.10, 2.49) for PFOS. Our findings indicate that serum perfluoroalkyl chemical levels are significantly associated with hyperuricemia in children even at the lower "background" exposure levels of the US general population.

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Industri pembuatan alat music memiliki risiko kesehatan akibat penggunaan bahan kimia seperti pelarut (solvent) dan perekat (adhesive). Pelarut digunakan dalam proses pengecatan kayu, sedangkan perekat digunakan untuk penyambungan part kayu agar menjadi sebuah alat musik. Pelarut yang digunakan yaitu 1,2,4-trimethylbenzene, 2-butoxyethanol, 2-ethoxyethyl acetate, 4-methylpentan-2-one, acetone, cumene, cyclohexanone, ethyl acetate, ethyl benzene, mesitylene, naphthalene, solvent naphtha (petroleum), n-butyl acetate, toluene, dan xylene. Penilaian risiko kesehatan bahan kimia mengacu pada Chemical Health Risk Assessment (CHRA) DOSH Malaysia tahun 2018 dengan pendekatan kualitatif dan kuantitatif. Pengumpulan data dimulai dari identifikasi bahan kimia, pengamatan dan interview, pengukuran, penilaian risiko kesehatan, menilai kecukupan pengendalian dan penentuan action priority. Hasil penelitian di PT XYZ menunjukkan nilai risk rating untuk pajanan inhalasi berkisar antara 6 (moderate) hingga 25 (high), dan pajanan dermal berada pada kategori moderate 1, moderate 2 dan high 1. Seluruh proses dinyatakan belum memiliki pengendalian yang cukup. Action priority 1 untuk pajanan inhalasi pada proses sanding, washcoat, wipping, pemasangan logo dan pewarnaan dengan cat pada bahan kimia cumene dan untuk pajanan dermal pada proses sanding, washcoat, wipping, pemasangan logo dan pewarnaan dengan cat pada bahan kimia 2-ethoxyethyl acetate, cumene, dan solvent naphtha (petroleum). Action priority 1 berarti tindakan pengendalian diperlukan segera.

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Abstrak: Laboratorium X adalah salah satu fasilitas di Fakultas Kedokteran dan IlmuKesehatan (FKIK) UIN Jakarta yang menunjang fasilitas belajar dalam pendidikan.Berdasarkan hasil pendataan awal, terdapat 120 bahan kimia yang terdapat dalamlaboratorium X ini. Hasil studi pendahuluan belum memadainya upaya pengendalianyang dijalankan seperti belum tersedianya MSDS (Material Safety Data Sheet) secaralengkap di Laboratorium X, pelabelan yang belum tepat, penggunaan APD (AlatPelindung Diri) yang belum sesuai dan lain-lain diperkirakan dapat meningkatkanrisiko keselamatan dan kesehatan kerja (K3) di Laboratorium X ini.Penelitian ini dilakukan untuk mengidentifikasi, analisa dan evaluasimanajemen laboratorium pada aspek keselamatan dan kesehatan kerja diLaboratorium X FKIK UIN Syarif Hidayatullah Jakarta tahun 2016 denganmenggunapan beberapa standar acuan. Penelitian ini bersifat kualitatif denganmelakukan observasi, wawancara serta telaah dokumen. Penelitian ini dilakukan daribulan April-Juni 2016.Hasil penelitian menunjukkan beberapa elemen masih belum sesuai denganstandar manajemen laboratorium yaitu belum tersedianya draft sistem manajemen dansystem manajemen mutu laboratorium, belum adanya sistem transportasi danpenerimaan bahan kimia, lemari penyimpanan bahan kimia yang belum sesuai, sistemtanggap darurat yang belum lengkap, belum dilakukannya penilaian manajemenresiko dan biomonitoring pada pekerja.Saran yang dapat diberikan yaitu Penting harus segera dilakukan adalahmenyusun kembali system manajemen lab, Menyusun system manajemen mutu,Menyusun Sistem Tanggap Darurat dan Pelatihan keadaan darurat di Lab, MelakukanPenilaian Risiko yang ada di lab secara menyeluruh dan Melakukan pemeriksaankesehatan pada pegawai secara berkala.Kata Kunci : system manajemen laboratorium, system manajemen mutulaboratorium, keselamatan dan kesehatan kerja, bahan kimia

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Laboratory X is one of the facilities in Faculty of Medicine and Health Sciences(FKIK) UIN Jakarta that support learning in educational. Based on the initial data,there are 120 chemicals contained in this X lab. Results of a preliminary study ofinadequate control measures undertaken such as the placement of chemicalsubstances that have not been right, not completely of MSDS (Material Safety DataSheet), labeling is not proper, use of PPE (Personal Protective Equipment) is notappropriate and others are expected to increase the risk of occupational safety andhealth in this laboratory.This study was done to identify, analyze and evaluate laboratory management aspectsof Health and Safety in the Laboratory X FKIK UIN Syarif Hidayatullah Jakarta in2016 with some reference standards. This is a qualitative study by observation,interviews and review of documents. This research was conducted from April to June2016.The results showed some elements are still not in accordance with the standards ofthe laboratory management, such as the unavailability of draft management systemsand quality management system of the laboratory, no transport system and acceptanceof chemicals, chemicals storage are not appropriate, emergency response system thatis not yet complete, never done risk management assessment and biomonitoring ofworkers.Faculty is advised that is important has to be done is rearrange the systemmanagement lab, Develop quality management systems, Develop EmergencyResponse System and Training of emergency in the Lab, Conducting RiskAssessment in the lab thoroughly and Perform health checks on employees on aregular basis.Keywords: laboratory management system, laboratory quality management systems,occupational health and safety, chemicals.

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