Ditemukan 59 dokumen yang sesuai dengan query :: Simpan CSV
ABSTRAK Latar Belakang: Terapi ARV pada ODHA diharapkan dapat menurunkan angka kematian dan kesakitan serta menekan penularan HIV. Untuk mencapai tujuan MDG’s tahun 2015, diharapkan 90% ODHA sudah mendapatkan terapi ARV secara teratur. RSUD Arifin Achmad Pekanbaru telah memberikan terapi ARV sejak tahun 2004 tetapi belum pernah diteliti pengaruh ARV terhadap survival pasiennya. Metode : Penelitian ini menggunakan desain studi kohort retrospektif dengan 319 sampel dan dilakukan selama Mei-Juni 2013. Data penelitian diperoleh melalui data rekam medis RS. Data dianalisis dengan menggunakan analisis survival metode Kaplan-Meier dan dilanjutkan dengan analisis multivariate Hasil: Penelitian menunjukkan bahwa pasien yang memakan ARV secara teratur memiliki survival yang lebih baik. Pasien yang tidak memakan ARV atau memakan ARV tetapi tidak teratur, memiliki risiko kematian sebesar 42,5 kali lebih besar jika dibandingkan dengan pasien yang memakam ARV secara teratur. (p=0,01, 95%CI: 13-138). Jumlah kematian selama pengamatan hanya 5,8% pada kelompok yang teratur memakan ARV, sedangkan pada kelompok yang tidak mencapai 28%. Faktor lain yang turut meningkatkan survival adalah jumlah CD4 pada awal pengobatan >100 sel/mm³(p=0,01, HR=4,39, 95% CI(1,8-10,5). Walaupun kurang bermakna secara statistik, perlu mempertimbangkan pemberian ARV pada stadium klinis awal sebagai faktor yang turut meningkatkan survival ODHA mengingat stadium klinis dapat diperiksa di semua layanan kesehatan. (p=0,07, HR=2.3, 95%CI 0,9-5.6). Faktor pendidikan secara statistik juga bermakna membedakan survival pasien. Dalam penelitian ini stadium klinis dibuktikan sebagai confounding. Hal yang disarankan adalah meningkatkan cakupan penemuan dan tatalaksana dini kasus HIV/AIDS dengan melakukan pelacakan pada semua kasus mangkir, meningkatkan kepatuhan memakan ARV dan mengupayakan pendampingan kasus secara maksimal.
ABSTRACT Background: ARV for HIV or AIDS patients is a hope to reduce the mortality, morbidity and to prevent the transmissions. To achieve the MDG the minister of health need to cover 90% AIDS people with ARV adherently. RSUD Arifin Achmad Pekanbaru have giving the therapy for AIDS patients since 2004, but have never studied the survival analysis and another factors that contribute to yet. Method: This study is a cohort retrospective design, with 319 samples. Take place in Arifin Achmad Hospital Of Pekanbaru, Riau Province in May-June 2013. The resource are medical record of HIV/AIDS patiens in VCT clinic. Was analyse by Kaplan-Meier survival analysis and then for further use multivariate analyses. Result: The study show that the survival of patiens who take ARV adherently is higher than the other one. The patients who no used ARV adherently will have mortality rate 42,5 times than the patients that used ARV addherently. (p=0,01, 95%CI: 13-138). The deaths amount only 5,8% on the adherently ARV patients, but at another side, the deaths amount increase by 28%. Another factor that contribute to increase the survival are CD4 amounts at the beginning of therapy that >100 sel/mm³(p=0,01, HR=4,39, 95% CI(1,8-10,5). We need to consider the clinical of AIDS stadium as one of factor that contribute to increase the survival too if use ARV at the beginner of clinical stadium. (p=0,07, HR=2.3, 95%CI 0,9-5.6). The educations level has the value statistically to distinguish the survival. In this study, the clinical stadium is a confounder. We sugest to improve the early detection and prompt treatment by tracking the lost of follow up patients, increase the adherent of ARV and by mentoring or”buddy” programe for all HIV cases.
In 2022, Indonesia ranked fourth globally in the number of breast cancer deaths. One of the contributing factors to the high mortality rate is comorbidity. This study aims to examine the association between comorbidities and three-year survival of breast cancer patients in Indonesia. A retrospective cohort design was used, involving 896 samples from the 2018–2023 BPJS Kesehatan General Sample Data. Survival curves and probabilities were estimated using the Kaplan-Meier method, while associations were analyzed using the log-rank test and Hazard Ratios (HR) via Cox regression. The study found that the cumulative survival probability (CSP) at 36 months for the overall sample was 49.9%, with a median survival time of 35,34 months. Breast cancer patients with comorbidities and other comorbid conditions had a higher risk of death within three years (comorbidity CSP = 43.7%; HR = 1.38; 95% CI = 1.01–1.89, other comorbidities CSP = 42.4%; HR = 1.43; 95% CI = 1.01–2.04). No significant differences in survival were found based on metabolic disorders including diabetes, hypertension, cardiovascular disease, age at diagnosis, marital status, socioeconomic status, or place of residence. Breast cancer survival in Indonesia remains low, particularly among patients with comorbidities.
Objective: This study aims to determine the risk of recurrent strokein patientswith post-stroke first in the brain center of the national hospitaland the risk factorsthat influence.Methods: This study was a retrospective cohort. The sample in this study is thefirst to attack all stroke patients who underwent inpatient services in 2014 and hada complete medical record. Analysis of data using multivariate cox regression.Results: The results showed that in ≤ 15, ≥ 60 years of age have a greater risk forrecurrent stroke; in <15 overweight have a higher risk for recurrent stroke; in ≤15, obesity have a higher risk for recurrent stroke; in ≤ 30, pre-hypertension are athigher risk forrecurrent stroke; in ≤ 15, hypertension grade 1 and 2 have a higherrisk for the recurrent stroke; control irregular had 8.71 times higher risk forrecurrent strokeKey words : Survival analysis, reccurrent stroke, stroke.
