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Asam urat merupakan produk akhir dari metabolisme purin. Nilai normal asam urat serum pada wanita adalah 4,0 ± 1,0 mg/dl dan pada laki - laki 5,1 ± 1,0 mg / dl. Kadar asam urat dapat disebabkan oleh beberapa faktor diantaranya adalah karakteristik responden (usia, jenis kelamin, tingkat pendidikan, pengetahuan), asupan zat gizi (purin, protein, vitamin C, lemak, serat, asam folat),gaya hidup (kopi, soft drinks, olah raga, merokok) dan IMT. Tujuan dari penelitian ini adalah untuk mengetahui faktor determinan terhadap kadar asam urat pada kelompok orang dewasa di Desa Pabuaran Gunung Sindur Bogor.
Disain penelitian yang digunakan adalah cross-sectional dengan sampel sebanyak 66 responden. Penelitian dilakukan pada bulan Mei-Juni 2012. Analisis statistik deskriptif pada data numerik disajikan dalam bentuk rata-rata ± SD, sedangkan data nominal dan ordinal dalam bentuk proporsi.
Analisis statistik inferensial menggunakan uji t independen, ANOVA, korelasi pearson product moment dan regresi linear ganda dilakukan untuk mengetahui faktor dominan. Rata-rata kadar asam urat responden 4,64 ± 1,19 mg/dl dengan rata-rata kadar asam urat pria yaitu 5,88 ± 1,30 dan wanita yaitu 4,31 ± 0,92. Terdapat hubungan yang signifikan antara jenis kelamin dan merokok dengan kadar asam urat. IMT merupakan faktor dominan terhadap kadar asam urat setelah dikontrol usia, jenis kelamin, tingkat pendidikan, asupan purin rendah, dan asupan vitamin C.
Uric acid is the end product of purine metabolism. Normal level of serum uric acid for women is 4,0 ± 1,0 mg/dl and for men is 5,1 ± 1,0 mg / dl. An elevated uric acid level can be caused by several factors of which is respondents characteristics (age, gender, level of education, knowledge), nutrient intake (purine, protein, vitamin C, fat, dietary fiber, folic acid), life style (coffee, soft drinks, sport, smoking) and BMI. This research was aim to know determinant factor of uric acid level at group of adult in Pabuaran Countryside, Gunung Sindur Subdistrict, Bogor Regency.
Research design used by cross sectional study with 66 sample. This research was performed on May-June 2012. Descriptive statistic analysis on numeric data were presented as mean ± SD, while nominal and ordinal data in proportion.
Inferential statistic analysis with t test independen, ANOVA test, pearson product moment corellation was performed and multiple linear regression was used to know the dominant factor. Mean uric acid level was 4,64 ± 1,19 mg/dl with Mean uric acid consentration for men was 5,88 ± 1,30 dan for women was 4,31 ± 0,92. gender and smoking was significantly associated with uric acid level. BMI was dominance factor to uric acid level after controlled by age, sex, level of education, low purine intake and vitamin C intake.
Kata kunci: Kadar asam urat, Indeks Massa Tubuh, uji diagnostik
This thesis discusses about the dominant factor uric acid level among Satuan Polisi Pamong Praja in Working Area of East Jakarta and diagnostic test of BMI (Body Mass Index) and WC (Waist Circumference) to detecting the abnormal uric acid levels earlier. The total sample of this study is 150 people. This is a quantitative study with cross sectional design. Data analysis using multiple linier regression. The result of this study revealed that Body Mass Index is the dominant factor of uric acid level and the measurement of BMI can be used as a screening test instrument for abnormal uric acid level with cut off point 26,36% kg/m2 and sensitivity 63,6%.
Keyword: Uric acid Level, Body Mass Index, Diagnostic test
Hypertension is one of the non-communicable diseases with a continuously increasing prevalence, particularly among the adult population in urban areas such as Jakarta. This study aims to examine the relationship between dietary factors (sodium, fat, fiber, potassium), Body Mass Index (BMI), and lifestyle factors (physical activity, smoking, and stress) with the incidence of hypertension, as well as to identify the dominant factors influencing hypertension among adults aged 45–59 years in Kemayoran District, Central Jakarta. A cross-sectional study design was employed, involving a total of 153 respondents. Data were collected through questionnaires and direct measurements. Data analysis was conducted using chi-square tests and logistic regression. The results showed a hypertension prevalence of 54.9% among respondents, indicating that more than half of individuals in this age group were affected by hypertension. Multivariate analysis, which included sodium intake, fat intake, fiber intake, physical activity, smoking, and stress, revealed that sodium intake (p = 0.025; OR = 2.276) and smoking (OR = 2.805) were the dominant contributing factors to hypertension.
Gangguan kepadatan tulang (osteoporosis dan osteopenia) merupakan masalah kesehatan masyarakat utama yang disebabkan oleh banyak faktor. Tujuan dari penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan gangguan kepadatan tulang pada kelompok usia dewasa (30-55 tahun) di daerah urban dan rural terpilih Provinsi Jawa Barat tahun 2012. Disain penelitian yang digunakan adalah cross-sectional dengan sampel sebanyak 142 responden. Penelitian dilakukan pada bulan Mei-Juni 2012 di Pesona Khayangan, Kecamatan Sukmajaya, Kota Depok sebagai daerah urban dan Desa Pabuaran, Kecamatan Gunung Sindur, Kabupaten Bogor sebagai daerah rural Provinsi Jawa Barat. Prevalensi gangguan kepadatan tulang dalam penelitian ini sebesar 31,7% (4,2% osteoporosis dan 27,5% osteopenia).
Hasil analisis bivariat menunjukkan proporsi gangguan kepadatan tulang lebih banyak pada responden yang berusia ≥50 tahun (p-value=0,047) dan yang memiliki IMT <23,49 kg/m2 (p-value=0,003). Hasil analisis multivariat menunjukkan bahwa responden yang memiliki IMT <23,49 kg/m2 akan mengalami gangguan kepadatan tulang sebesar 5,5 kali lebih tinggi dibandingkan dengan responden yang memiliki IMT >27,36 kg/m2 dan responden yang memiliki IMT 23,49-27,36 kg/m2 akan mengalami gangguan kepadatan tulang sebesar 2,2 kali lebih tinggi dibandingkan dengan responden yang memiliki IMT >27,36 kg/m2 setelah dikontrol variabel usia, asupan vitamin D dan asupan protein.
Pada penelitian ini, IMT merupakan faktor yang paling berhubungan dengan gangguan kepadatan tulang setelah dikontrol variabel usia, asupan vitamin D dan asupan protein. Semakin rendah IMT, semakin tinggi risiko gangguan kepadatan tulang.
Bone density disorder (osteoporosis and osteopenia) is a major public health problem caused by multifactor. The purpose of this study was to find out factors related to adult bone density disorder (30-55 years of age) in the selected urban and rural area, West Java Province, 2012. It used cross-sectional method and the sample was 142 respondents. The data was taken on May-June 2012 in Pesona Khayangan, Kecamatan Sukmajaya, Kota Depok as the urban area and Desa Pabuaran, Kecamatan Gunung Sindur, Kabupaten Bogor as the rural area. Prevalence of bone density disorder in this study was 31,7% (4,2% osteoporosis and 27,5% osteopenia).
Bivariate analysis showed higher proportion of bone density disorder in respondent aged ≥50 years (p-value=0,047) and BMI <23,49 kg/m2 (p-value=0,003). Multivariate analysis verified that respondent with BMI <23,49 kg/m2 will 5,5 times higher to have bone density disorder than respondent with BMI >27,36 kg/m2 and respondent with BMI 23,49-27,36 kg/m2 will 2,2 times higher to have bone density disorder than respondent with BMI >27,36 kg/m2 after controlled by age, vitamin D and protein intake variable.
In this study, BMI is the most related factor of bone density disorder after controlled by age, vitamin D and protein intake variable. The lower BMI, the higher risk of bone density disorder.
Kata kunci:IMT/U, obesitas, persen lemak tubuh, siswa SMA.
