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Previous studies have reported that there are long-term effects of quitting smoking on weight gain which also exacerbate prehypertension, but the effects are unclear. This study aims to determine the association of smoking and obesity on the incidence of prehypertension in young adults in Indonesia. This quantitative research is a cross-sectional analytic study using secondary data from Riskesdas 2018 with samples of 17,698 and Cox regression analysis. The results of this study explain that the prevalence of prehypertension in young adults in Indonesia is 52.61%. Multivariate analysis showed non-smokers and obese young adults had the greatest risk of developing prehypertension, which was 1.33 times. However, a decreasing effect was found in young adults who smoked and were obese on the incidence of prehypertension, which was 1.17 times, and a protective effect was found in those who smoked and were not obese (PR=0.88) due to the antagonistic interaction of smoking and obesity on prehypertension by 3.42%. Check blood pressure using applications on smartwatches and smartphones in young adults who smoke and focus on those who are obese plus increasing the implementation of Posbindu PTM in public places and promoting health through social media.
Coronavirus Disease 2019 (COVID-19) is a new infectious disease which has been a pandemic for almost three years (2020-2023). One of the risk factors for COVID-19 mortality is a history of comorbid hypertension. This study was conducted to determine the relationship between comorbid hypertension and mortality among COVID-19 confirmed cases in Indonesia for the period January-June 2022 by comprehensively controlling potential confounder variables, more complete data sources and a larger sample size. The study design was a case control study. Data sourced from the Ministry of Health's Online Hospital Information System (SIRS Online) report for the period January-June 2022. Confirmed cases of COVID-19 with comorbid hypertension have a significantly higher risk of death by 1,57 times compared to confirmed cases COVID-19 without comorbid hypertension after controlling for age, vaccination status, viral variants, and diabetes mellitus (OR=1,57; 95%CI:1,20-2,05; p=0,001). There was a difference risk of death in the non-Omicron infection group (OR=7,68; 95%CI:1,15-51,38; p=0,036) and Omicron group (OR=1,52; 95%CI:1,16-1,99; p=0,002) after controlling for age, vaccination status, and diabetes mellitus. There was a difference risk of death in the unvaccinated group (OR=1,52; 95%CI:1,02-2,26; p=0,037), 1-dose vaccine group (OR=1,85; 95%CI:0,84-4,08; p=0,125), 2-dose vaccine group (OR=1,66; 95%CI:1,08-2,54; p=0,020) and booster vaccine group (OR=0,21; 95%CI:0,03-1,48; p=0,118) after controlling for age, viral variants, and diabetes mellitus. Joint efforts from the government and community are needed in the prevention and control of comorbid hypertension to prevent mortality from COVID-19 infection.
Keywords: Hypertension, Fast Food, Soft Drink, Meat and IFLS-5.
Coronary Heart Disease (CHD) remains a major cause of morbidity and mortality in women in Indonesia. The global epidemic of obesity contributes to the increase of cardiovascular events. In Indonesia, there have not been many studies evaluate the association between abdominal obesity and CHD in women. Therefore, this study aims to determine the association between abdominal obesity and CHD in women aged 25-65 years in Bogor. This retrospective cohort study involves 2.451 respondents of FRPTM Cohort Study who met the inclusion and exclusion criteria with an observation period of 6 years. The main independent variable of this study was abdominal obesity based on Waist-to-Height-Ratio (WHtR), while outcome of the interest was CHD based on the results of interview and/or ECG results. Cox regression analysis was performed to estimated Hazard Ratio (HR) with a 95% Confidence Interval (95% CI). The results showed that the incidence rate of CHD in women was 19 per 1.000 person-years. Women with abdominal obesity were 1,38 times (95% CI 1,01-1,89) more likely to have CHD than those without abdominal obesity after adjustment for age, hypertension, and menopause status. Early detection of CHD risk factor, especially abdominal obesity, is important, so that prevention and lifestyle modification can be implemented immediately.
Diabetes Mellitus tipe 2 merupakan salah satu masalah kesehatan yang sangat serius akibat setiap tahun terjadi peningkatan dan salah satu kontributor terhadap angka kesakitan dan kematian akibat penyakit tidak menular di seluruh dunia. 90% Diabetes Mellitus yang di diagnosis adalah DM tipe 2. Perubahan pola hidup yang ditandai dengan meningkatnya obesitas khususnya obesitas sentral merupakan salah satu risiko terhadap terjadinya Diabetes Mellitus tipe 2. Penelitian ini bertujan untuk mengetahui hubungan obesitas sentral terhadap kejadian Diabetes Mellitus Tipe 2 di Kelurahan Johar Baru Kecamatan Johar Baru Jakarta Pusat. Penelitian dilakukan dengan desain Cross Sectional Analitik, dengan menggunakan data Program skrining Penyakit Tidak Menular (PTM) Direktorat PTM Dirjen P2PL Kemenkes RI tahun 2012. Responden dalam penelitian ini berusia 20 tahun keatas. Analisis data menggunakan stratifikasi dan analisis multivariat menggunakan cox regression.
Hasil analisis data diperoleh prevalensi DM tipe 2 sebesar 18,1% dan obesitas sentral sebesar 57,7%. Selain itu, hasil multivariat menunjukkan bahwa orang dengan obesitas sentral (Waist Circumference (WC) P>90 cm, dan W>80 cm) berisiko 1,47 kali (PR= 1,47; 95% CI 0,606 - 3,575) terhadap kejadian DM tipe2 setelah di kontrol variabel jenis kelamin, IMT, dan aktivitas fisik. Namun setelah mengikutkan efek interaksi antara obesitas sentral dan aktivitas fisik diketahui bahwa orang yang obesitas sentral dan beraktivitas rendah (< 300 Mets) berisiko 7,59 (PR=7,59; 95% CI, 1,656 - 34,77) kali terhadap kejadian diabetes mellitus tipe 2. Dengan melakukan intervensi atau mencegah obesitas sentral dapat mencegah 23,98 % kejadian diabetes mellitus tipe 2 di populasi studi. Usaha untuk deteksi dini dengan skrining pada orang obesitas khususnya obesitas sentral membantu dalam menjaring kasus DM tipe 2, dan pola hidup sehat dan peningkatan aktivitas fisik dapat mencegah terjadinya obesitas sehingga menurunkan angka kejadian diabetes mellitus tipe 2.
Diabetes Mellitus categorized into serious health problems due to the increasing of its prevalence every year. It is one of the contributors to the global burden of disease and mortality in the world, where 90% of this disease was type II Diabetes. Changing of people lifestyle was one of the risk factors to the increasing of the disease in community. The objective of this study was to investigate the association between abdominal obesity and type II DM in Johar Baru Sub-district, Central Jakarta. This is a cross sectional study, utilized the data from the result of screening by direktorat PTM dirjen P2PL kemenkes RI. The inclusion criteria was Johar baru resident whom their ages more than 20 years. The data analysis was performed with stratification and cox regression multivariate analysis.
The results of study showed the prevalence of type II DM was 18,1%, meanwhile the prevalence of abdominal obesity was 57,7%. The result of multivariate analysis showed that the people with abdominal obesity (waist circumference P> 90 CM and W> 80 cm) had 1,47 risk to get type II DM compared to the people who did not, after controlling for covariates, Included: Sex, IMT and Physical activity (PR= 1,47; 95% CI: 0,606-3,575). However, after including the interaction effect between abdominal obesity and physical activity, it is showed the people with abdominal obesity and light physical activity had the risk 7,59 (PR=7,59; 95% CI, 1,656 - 34,77) to get type II diabetes. The result of analysis showed, with intervention or prevention of abdominal obesity can prevent 23,98 % type II DM in community. Screening one of the strategies as the early detection of people with type II DM. Healthy life style and having more physical activity could prevent the obesity and it is expected to reduce the prevalence of type II DM.
Kematian pasien Penyakit Ginjal Kronik (PGK) pada usia dewasa yang menjalankan hemodialisis setelah tiga bulan adalah jarang. Namun, masih mungkin terjadi. Padahal layanan hemodialisis dibutuhkan seumur hidup. Tujuan studi ini adalah engetahui faktor – faktor risiko yang berhubungan dengan kematian pasien PGK usia dewasa yang menjalankan hemodialisis reguler. Metode yang digunakan adalah kasus kontrol tanpa pencocokkan dengan perbandingan 1:2. Uji statistik yang digunakan adalah regresi logistik. Faktor risiko yang berhubungan terhadap kematian adalah riwayat gagal jantung (OR = 2,3; IK 95% = 1,2 – 4,4; nilai p = 0,009), riwayat obstruksi pasca ginjal (OR = 3,5; IK 95% = 1,6 – 7,6; nilai p = 0,002), glukosa sewaktu ≥140 mg/dl (OR = 2,1; IK 95% = 1,2 – 3,6; nilai p = 0,011), Gangguan Ginjal Akut (GGA) (OR = 6,5; IK 95% = 3,8 – 11,1; nilai p = 0,000), dan Indeks Massa Tubuh (IMT) <18,5 kg/mm2 (OR = 3,0; IK 95% = 1,2 – 7,6; nilai p = 0,019).
Faktor – faktor risiko yang berhubungan dengan kematian pasien PGK pada usia dewasa yang menjalankan hemodialisis reguler adalah riwayat gagal jantung, riwayat obstruksi pasca ginjal, glukosa sewaktu ≥140 mg/dl, GGA, dan IMT <18,5 kg/mm2
Mortality of Chronic Kidney Disease (CKD) patients in adults undergoing hemodialysis after three months is rare. However, it is still possible. Even though hemodialysis services are needed for life. The objective of this study is to determine the risk factors associated with the death of adult CKD patients undergoing regular hemodialysis. The study design was unmatched control case with a ratio of 1:2. The statistical test used was logistic regression. Risk factors were history of heart failure (OR = 2.3; CI 95% = 1.2 – 4.4; p value = 0.009), history of obstruction post renal (OR = 3.5; CI 95% = 1.6 – 7.6; p value = 0.002), random glucose ≥140 mg/dl (OR = 2.1; CI 95% = 1.2 – 3.6; p value= 0.011), Acute Kidney Injury (AKI) (OR = 6.5; CI 95% = 3.8 – 11.1; p value = 0.000), and Body Mass Index