Latar belakang: Hipertensi menjadi penyebab kematian dini tertinggi di seluruh dunia dan merupakan faktor risiko utama untuk penyakit kardiovaskular termasuk di Indonesia. Jawa Barat merupakan provinsi dengan angka prevalensi hipertensi tertinggi di Indonesia yaitu sebesar 34,4% berdasarkan hasil pengukuran tekanan darah dan sebesar 10,7% berdasarkan diagnosis dokter yang menjadikan Jawa Barat sebagai provinsi terbesar ketiga dengan prevalensi hipertensi terbanyak pada penduduk berusia ≥ 18 tahun. Dalam penanganan penyakit hipertensi, indikator terkait terapi atau pengobatan hipertensi merupakan salah satu faktor yang penting untuk diperhatikan. Data terbaru yang diperoleh dari Survei Kesehatan Indonesia (SKI) tahun 2023 menunjukkan bahwa ketidakpatuhan konsumsi obat antihipertensi di Jawa Barat mencapai 53,8% dengan 35,5% pasien tidak teratur minum obat dan 18,3% tidak minum obat sama sekali. Rendahnya kepatuhan pasien hipertensi untuk konsumsi obat antihipertensi masih menjadi masalah dalam penanganan hipertensi di Indonesia terutama di Jawa Barat. Tujuan: Penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan dengan ketidakpatuhan konsumsi obat antihipertensi pada pasien hipertensi berusia ≥ 18 tahun di Jawa Barat.  Metode: Penelitian ini menggunakan desain studi cross-sectional dengan analisis univariat dan bivariat. Hasil: Prevalensi ketidakpatuhan konsumsi obat antihipertensi pada pasien hipertensi usia ≥ 18 tahun di Jawa Barat adalah 53,1% dengan “merasa sudah sehat” menjadi alasan tertinggi ketidakpatuhan. Faktor yang signifikan berhubungan dengan ketidakpatuhan konsumsi obat antihipertensi meliputi berusia 18 - 59 tahun (PR = 1,23; 95% CI = 1,06 - 1,47), memiliki tingkat pendidikan rendah (PR = 1,17; 95% CI = 1,09 - 1,27), tidak memiliki jaminan kesehatan (PR = 1,26; 95% CI = 1,18 - 1,36), merokok (PR = 1,12; 95% CI = 1,04 - 1,21), tidak memiliki pengetahuan terkait konsumsi obat antihipertensi (PR = 1,88; 95% CI = 1,72 - 1,97). Kesimpulan: Pemerintah perlu meningkatkan edukasi kesehatan dan menekankan pentingnya rutin mengonsumsi obat antihipertensi meskipun tidak merasakan gejala. Selain itu, diperlukan kerja sama lintas sektor untuk mendukung pencegahan ketidakpatuhan konsumsi obat antihipertensi.

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Background: Hypertension is the leading cause of premature death worldwide and is a major risk factor for cardiovascular diseases, including in Indonesia. West Java is the province with the highest prevalence of hypertension in Indonesia, with a rate of 34.4% based on blood pressure measurements and 10.7% based on doctor diagnoses. This makes West Java the third largest province in terms of hypertension prevalence among individuals aged ≥ 18 years. In managing hypertension, indicators related to hypertension therapy or medication are crucial factors that need attention. Recent data from the Indonesia Health Survey (SKI) shows that non-adherence to antihypertensive medication in West Java reaches 53.8%, with 35.5% of patients taking medication irregularly and 18.3% not taking medication at all. The low level of adherence among hypertensive patients to taking antihypertensive medication remains a significant issue in hypertension management in Indonesia, particularly in West Java. Objective: This study aims to identify the factors associated with non-adherence to antihypertensive medication among hypertensive patients aged ≥ 18 years in West Java. Methods: This research used a cross-sectional study design with univariate and bivariate analyses. Results: The prevalence of non-adherence to antihypertensive medication among hypertensive patients aged ≥ 18 years in West Java is 53.1%, with “feeling healthy” being the most common reason for non-adherence. Significant factors associated with non-adherence to antihypertensive medication include: being aged 18–59 years (PR = 1.23; 95% CI = 1.06–1.47), having a low education level (PR = 1.17; 95% CI = 1.09–1.27), lacking health insurance (PR = 1.26; 95% CI = 1.18–1.36), smoking (PR = 1.12; 95% CI = 1.04–1.21), and lacking knowledge related to antihypertensive medication (PR = 1.88; 95% CI = 1.72–1.97). Conclusion: The government needs to enhance health education and emphasize the importance of regularly taking antihypertensive medication, even when no symptoms are present. Additionally, cross-sector collaboration is necessary to support the prevention of non-adherence to antihypertensive medication.

Penyakit Jantung Koroner (PJK) masih menjadi penyebab utama kesakitan dan kematian pada perempuan di Indonesia. Epidemi obesitas yang terjadi secara global ikut berkontribusi pada meningkatnya kejadian kardiovaskular. Di Indonesia, belum banyak studi yang mempelajari hubungan obesitas sentral dengan PJK pada perempuan. Oleh karena itu, penelitian ini bertujuan untuk mengetahui hubungan antara obesitas sentral dengan kejadian PJK pada perempuan usia 25-65 tahun di Kota Bogor. Penelitian kohort retrospektif ini mengikutsertakan 2.451 responden Studi Kohor FRPTM yang memenuhi kriteria inklusi dan eksklusi dengan masa pengamatan selama 6 tahun. Pajanan utama yang diteliti adalah obesitas sentral berdasarkan rasio Lingkar Pinggang - Tinggi Badan (LPTB), dengan outcome berupa PJK yang ditegakkan berdasarkan hasil wawancara responden dan/atau hasil EKG. Analisis multivariat dengan Cox Regression dilakukan untuk mengestimasikan Hazard Ratio (HR) dengan 95% Confidence Interval (95% CI). Hasil penelitian menunjukkan insiden rate PJK pada perempuan adalah sebesar 19 per 1.000 orang-tahun. Perempuan dengan obesitas sentral memiliki risiko 1,38 kali (95% CI 1,01-1,89) lebih tinggi dibanding yang tidak obesitas sentral untuk mengalami PJK setelah mengontrol variabel usia, hipertensi, dan status menopause. Deteksi dini faktor risiko PJK, terutama obesitas sentral, penting dilakukan agar upaya pencegahan dan perubahan perilaku dapat segera dilakukan.

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Coronary Heart Disease (CHD) remains a major cause of morbidity and mortality in women in Indonesia. The global epidemic of obesity contributes to the increase of cardiovascular events. In Indonesia, there have not been many studies evaluate the association between abdominal obesity and CHD in women. Therefore, this study aims to determine the association between abdominal obesity and CHD in women aged 25-65 years in Bogor. This retrospective cohort study involves 2.451 respondents of FRPTM Cohort Study who met the inclusion and exclusion criteria with an observation period of 6 years. The main independent variable of this study was abdominal obesity based on Waist-to-Height-Ratio (WHtR), while outcome of the interest was CHD based on the results of interview and/or ECG results. Cox regression analysis was performed to estimated Hazard Ratio (HR) with a 95% Confidence Interval (95% CI). The results showed that the incidence rate of CHD in women was 19 per 1.000 person-years. Women with abdominal obesity were 1,38 times (95% CI 1,01-1,89) more likely to have CHD than those without abdominal obesity after adjustment for age, hypertension, and menopause status. Early detection of CHD risk factor, especially abdominal obesity, is important, so that prevention and lifestyle modification can be implemented immediately.

Hypertension is one of the leading causes of premature death globally, and its prevalence remains high in Indonesia. Central obesity has been identified as a significant risk factor for hypertension, including among high-risk groups such as Hajj pilgrims. This study aimed to analyze the association between central obesity and stage 1 hypertension in Hajj pilgrims from Banten Province in 2024. A cross-sectional design was conducted using Siskohatkes RI health examination data from Hajj pilgrims aged 20–70 years in Banten Province in 2024 who met the inclusion and exclusion criteria (N=4,650). A modified Cox regression analysis was conducted to estimate the Prevalence Ratio (PR) and 95% Confidence Interval (CI) derived from the Hazard Ratio (HR). The prevalence of stage 1 hypertension among Hajj pilgrims in Banten Province in 2024 was 34.37%. The proportion of stage 1 hypertension was higher among pilgrims with central obesity (38.11%) compared to those without central obesity. After controlling for Body Mass Index (BMI), central obesity was found to increase the risk of stage 1 hypertension by 1.12 times (95% CI: 1.00–1.27). Central Obesity increases the risk of stage one hypertension with age appearing earlier in younger females and later in pre-elderly males. Central obesity has a significant association with an increased risk of stage 1 hypertension among Hajj pilgrims from Banten Province in 2024. These findings show that the importance of early detection and intervention of central obesity in the prevention of hypertension, especially in high-risk populations.